Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Lehua Li"'
Autor:
Weifeng Mi, Xiaolan Di, Yiming Wang, Huafang Li, Xiufeng Xu, Lehua Li, Huaning Wang, Guoqiang Wang, Kerang Zhang, Feng Tian, Jiong Luo, Chanjuan Yang, Yunfei Zhou, Shiping Xie, Hua Zhong, Bin Wu, Dong Yang, Zhenhua Chen, Yi Li, Jindong Chen, Shuyun Lv, Qizhong Yi, Zhiwei Jiang, Jingwei Tian, Hongyan Zhang
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Major depressive disorder (MDD) is the most prevalent form of depression and is becoming a great challenge for public health and medical practice. Although first-line antidepressants offer therapeutic benefits, about 35% of depressed patient
Externí odkaz:
https://doaj.org/article/58eb9933686944adb849594918ea939b
Autor:
Shen He, Yimin Yu, Jingjing Huang, Jiahui Yin, Yajuan Niu, Yazhou Lu, Bin Wu, Maosheng Fang, Xue Wang, Zhiping Tao, Lehua Li, Kan Li, Yan Li, Xiujuan Ding, Yifeng Shen, Huafang Li
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 13 (2023)
Background: Almost one-third of patients with major depressive disorder (MDD) do not respond to conventional antidepressants, and new treatments for MDD are urgently needed. Objectives: This phase IIb clinical trial was designed to evaluate the effic
Externí odkaz:
https://doaj.org/article/cb6e6a95267e423db2992f27683b93e2
Autor:
Xiaoxiao Shan, Wenli Zhao, Yan Qiu, Haishan Wu, Jindong Chen, Yiru Fang, Wenbin Guo, Lehua Li
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
This study aims to explore the potential benefits of antidepressant drugs related to metabolic enzyme and drug-targeted genes, identify the optimal treatment of major depression, and provide a reference for individualized medication selection. A pros
Externí odkaz:
https://doaj.org/article/61e0070266b3444a82e4986bb8f1a64c
Autor:
Jing Huang, Fangkun Liu, Bolun Wang, Hui Tang, Ziwei Teng, Lehua Li, Yan Qiu, Haishan Wu, Jindong Chen
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Schizophrenia is a chronic, debilitating neuropsychiatric disorder. Multiple transcriptomic gene expression profiling analysis has been used to identify schizophrenia-associated genes, unravel disease-associated biomarkers, and predict clinical outco
Externí odkaz:
https://doaj.org/article/59c3b2c00e7d478b9e33b56c4c51d919
Autor:
Jing Huang, Fangkun Liu, Hui Tang, Haishan Wu, Lehua Li, Renrong Wu, Jingping Zhao, Ying Wu, Zhixiong Liu, Jindong Chen
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Recent breakthroughs in human pluripotent stem cell-derived cerebral organoids provide a valuable platform for investigating the human brain after different drugs treatments and for understanding the complex genetic background to human pathology. Her
Externí odkaz:
https://doaj.org/article/d9b03dd512464be894b1b7188335276b
Publikováno v:
International Journal of Endocrinology, Vol 2013 (2013)
Schizophrenia is one of the most common global mental diseases, with prevalence of 1%. Patients with schizophrenia are predisposed to diabetes, coronary heart disease, hypertension, and osteoporosis, than the normal. In comparison with the metabolic
Externí odkaz:
https://doaj.org/article/6d28f363296f440491178f7905ed9d94
Autor:
Qian Zhao, Bingbing Fu, Nan Lyu, Xiangdong Xu, Guangbiao Huang, Yunlong Tan, Xiufeng Xu, Xuehua Zhang, Xueyi Wang, Zhiqiang Wang, Keqing Li, ZhenYu Hu, Hengfen Li, Hongbo He, Shuang Li, Jingyuan Zhao, Ruifeng He, Hua Guo, Yi Li, Lehua Li, Chuang Yang, Shaohong Zou, Bo Wei, Wenqiang Wang, Ce Chen, Zheng Lu, Shunqiang He, Qian Wang, Jinghua Zhao, Xiaoyue Pan, Zhenyu Pan, Junqing Li, Gang Wang
Publikováno v:
Journal of Affective Disorders. 329:72-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abbe6ede923d32abd856f187df94a58
https://doi.org/10.1016/j.jad.2023.02.067
https://doi.org/10.1016/j.jad.2023.02.067
Autor:
Lehua Li, Kai Yuan, Fude Yang, Jiong Luo, Feng Tian, Jielai Xia, Hongyan Zhang, Jingwei Tian, Qingrong Tan, Lin Lu, Xiufeng Xu, Weifeng Mi, Kerang Zhang, Jiahui Deng, Guoqiang Wang, Huafang Li
Publikováno v:
The international journal of neuropsychopharmacology. 25(3)
Background Ansofaxine (LY03005) extended-release tablet is a potential triple reuptake inhibitor of serotonin, norepinephrine, and dopamine. This study assessed the efficacy, safety, and appropriate dosage of ansofaxine for the treatment of major dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e6c3190a9f33e759c0c8a07947e929
https://pubmed.ncbi.nlm.nih.gov/34747448
https://pubmed.ncbi.nlm.nih.gov/34747448
Autor:
Fude Yang, Jiong Luo, Lehua Li, Kai Yuan, Lin Lu, Xiufeng Xu, Jingwei Tian, Hongyan Zhang, Qingrong Tan, Jielai Xia, Guoqiang Wang, Huafang Li, Jiahui Deng, Kerang Zhang, Feng Tian, Weifeng Mi
Publikováno v:
SSRN Electronic Journal.
BACKGROUND Ansofaxine (LY03005) extended-release (ER) tablet is a potential triple reuptake inhibitor of serotonin, norepinephrine, and dopamine. This study assessed the efficacy, safety, and appropriate dosage of ansofaxine for the treatment of majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e37a71ab9523a736effddb62e03cb34
https://doi.org/10.2139/ssrn.3894388
https://doi.org/10.2139/ssrn.3894388
Publikováno v:
European Neuropsychopharmacology. 27:48-58
Treatment effects of antipsychotic drugs on cerebral function are seldom examined. Exploring functional connectivity (FC) in drug-free schizophrenia patients before and after antipsychotic treatment can improve the understanding of antipsychotic drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7043509ca09322f40637b52125803806
https://doi.org/10.1016/j.euroneuro.2016.11.002
https://doi.org/10.1016/j.euroneuro.2016.11.002