Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

Autor: Fenton, TM, Kelly, A, Shuttleworth, EE, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, SL, Sheppard, D, Levison, S, Worthington, JJ, Lehtinen, MJ, Travis, MA

Publikováno v: Fenton, T, Kelly, A, Shuttleworth, E, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, S L, Sheppard, D, Levison, S, Worthington, J, Lehtinen, M J & Travis, M 2017, ' Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8 ', Mucosal Immunology . https://doi.org/10.1038/mi.2016.94
Mucosal immunology, vol 10, iss 3
Fenton, TM; Kelly, A; Shuttleworth, EE; Smedley, C; Atakilit, A; Powrie, F; et al.(2017). Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8. Mucosal Immunology, 10(3), 624-634. doi: 10.1038/mi.2016.94. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/38r6n90d

Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal T cells is transforming growth factor-β (TGFβ), which is secreted by cells as

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Interactions between the human milk oligosaccharide 2'-fucosyllactose and Bifidobacterium longum subspecies infantis in influencing systemic immune development and function in piglets.

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