Low-Density Lipoprotein Cholesterol Level Distributions Across Different Ages: Implications for Screening Children for Severe and Familial Hypercholesterolemia.

Autor: Liu J; Department of Population Health and Policy, Icahn School of Medicine at Mount Sinai, New York, NY (J.L.)., Bellows BK; Division of General Medicine, Columbia University Irving Medical Center, New York, NY (B.K.B., A.E.M., Y.Z.)., Jacobs DR Jr; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis (D.R.J., P.P.B., E.C.O.)., Woo JG; Department of Pediatrics, University of Cincinnati College of Medicine, OH (J.G.W.).; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, OH (J.G.W.)., Urbina EM; Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, OH (E.M.U.)., Balte PP; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis (D.R.J., P.P.B., E.C.O.)., Oelsner EC; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis (D.R.J., P.P.B., E.C.O.)., Kazi DS; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Division of Cardiology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA (D.S.K.)., Siscovick D; New York Academy of Medicine, New York (D.S.)., Allen NB; Department of Preventive Medicine (N.B.A., J.T.W.), Feinberg School of Medicine, Northwestern University, Chicago, IL., Rana JS; Division of Research (J.S.R.), Kaiser Permanente Northern California, Oakland.; Department of Cardiology (J.S.R.), Kaiser Permanente Northern California, Oakland., Wilkins JT; Department of Preventive Medicine (N.B.A., J.T.W.), Feinberg School of Medicine, Northwestern University, Chicago, IL.; Division of Cardiology, Department of Medicine (J.T.W.), Feinberg School of Medicine, Northwestern University, Chicago, IL., Hall ME; Department of Medicine, University of Mississippi Medical Center, Jackson (M.E.H.)., Bazzano LA; School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA (L.A.B.)., Burns TL; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City (T.L.B.)., Daniels SR; Department of Pediatrics, University of Colorado School of Medicine, Aurora (S.R.D.)., Dwyer T; Heart Research Group, Melbourne Children's Research Institute, Australia (T.D.).; Department of Pediatrics, University of Melbourne, Australia (T.D.).; Nuffield Department of Women's and Reproductive Health, Oxford University, England (T.D.)., Juonala M; Department of Medicine (M.J., J.S.A.V.), University of Turku, Finland.; Division of Medicine (M.J., J.S.A.V.), Turku University Hospital, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine (O.T.R., N.K., C.G.M.), University of Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine (O.T.R.), Turku University Hospital, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Finland (O.T.R., N.K., C.G.M.)., Sinaiko AR; Department of Pediatrics, University of Minnesota Medical School, Minneapolis (A.R.S., J.S.)., Steinberger J; Department of Pediatrics, University of Minnesota Medical School, Minneapolis (A.R.S., J.S.)., Venn AJ; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia (A.J.V.)., Kartiosuo N; Research Centre of Applied and Preventive Cardiovascular Medicine (O.T.R., N.K., C.G.M.), University of Turku, Finland.; Department of Mathematics and Statistics (N.K.), University of Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Finland (O.T.R., N.K., C.G.M.)., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories (T.L.), Tampere University, Finland.; Finnish Cardiovascular Research Center (T.L.), Tampere University, Finland.; Faculty of Medicine and Health Technology (T.L.), Tampere University, Finland., Magnussen CG; Research Centre of Applied and Preventive Cardiovascular Medicine (O.T.R., N.K., C.G.M.), University of Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Finland (O.T.R., N.K., C.G.M.).; Baker Heart and Diabetes Institute, Melbourne, Australia (C.G.M.)., Viikari JSA; Department of Medicine (M.J., J.S.A.V.), University of Turku, Finland.; Division of Medicine (M.J., J.S.A.V.), Turku University Hospital, Finland., de Ferranti SD; Department of Pediatrics, Harvard Medical School, Boston, MA (S.D.d.F.)., Moran AE; Division of General Medicine, Columbia University Irving Medical Center, New York, NY (B.K.B., A.E.M., Y.Z.)., Zhang Y; Division of General Medicine, Columbia University Irving Medical Center, New York, NY (B.K.B., A.E.M., Y.Z.).

Publikováno v: Circulation [Circulation] 2024 Nov 19; Vol. 150 (21), pp. 1741-1744. Date of Electronic Publication: 2024 Nov 18.

Genetic risk score for coronary artery calcification and its predictive ability for coronary artery disease.

Autor: Mishra PP; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Mishra BH; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Goebeler S; Forensic Medicine, Finnish Institute for Health and Welfare, Helsinki, Finland., Martiskainen M; Forensic Medicine, Finnish Institute for Health and Welfare, Helsinki, Finland.; Faculty of Medicine and Health Technology, Tampere University and Fimlab Laboratories, Tampere, Finland., Hakamaa E; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kleber ME; Vth Department of Medicine, University Medicine Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany., Delgado GE; Vth Department of Medicine, University Medicine Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany., März W; Vth Department of Medicine, University Medicine Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.; Synlab Academy, SYNLAB Holding Deutschland GmbH, Mannheim and Augsburg, Germany., Kähönen M; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere Finland., Karhunen PJ; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Lehtimäki T; Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.

Publikováno v: American journal of preventive cardiology [Am J Prev Cardiol] 2024 Oct 10; Vol. 20, pp. 100884. Date of Electronic Publication: 2024 Oct 10 (Print Publication: 2024).

Association of Serum Trimethylamine-N-Oxide Concentration from Childhood to Early Adulthood with Age and Sex.

Autor: Almer G; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Enko D; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Institute of Medical and Chemical Laboratory Diagnostics, General Hospital Hochsteiermark, Leoben, Austria., Kartiosuo N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Mathematics and Statistics, University of Turku, Turku, Finland., Niinikoski H; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Pediatrics and Adolescent Medicine, Turku University Hospital, University of Turku, Turku, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Munukka E; Microbiome Biobank, Institute of Biomedicine, University of Turku, Turku, Finland., Viikari J; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland., Rönnemaa T; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland., Rovio SP; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland., Mykkänen J; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Lagström H; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland., Jula A; Department of Public Health Solutions, Institute for Health and Welfare, Turku, Finland., Herrmann M; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, University of Turku and Turku University Hospital, Turku;Finland., Meinitzer A; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Pahkala K; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Paavo Nurmi Centre and Unit for Health and Physical Activity, University of Turku, Turku, Finland.

Publikováno v: Clinical chemistry [Clin Chem] 2024 Sep 03; Vol. 70 (9), pp. 1162-1171.

Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns.

Autor: Ciantar J; Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Marttila S; Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Gerontology Research Center, Tampere University, Tampere, Finland.; Tays Research Services, Wellbeing Services County of Pirkanmaa, Tampere University Hospital, Tampere, Finland., Rajić S; Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kostiniuk D; Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mishra PP; Department of Clinical Chemistry, Tays Research Services, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Tays Research Services, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mononen N; Department of Clinical Chemistry, Tays Research Services, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, Heidelberg University, Mannheim, Germany.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, Heidelberg University, Mannheim, Germany.; Synlab Academy, SYNLAB Holding Deutschland GmbH, Mannheim, Germany., Kähönen M; Department of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari O; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Lehtimäki T; Department of Clinical Chemistry, Tays Research Services, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitoharju E; Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Fimlab Laboratories, Tampere, Finland.

Publikováno v: Epigenetics [Epigenetics] 2024 Dec; Vol. 19 (1), pp. 2397297. Date of Electronic Publication: 2024 Sep 01.

The association between GRACE score at admission for myocardial infarction and the incidence of sudden cardiac arrests in long-term follow-up - the MADDEC study.

Autor: Hautamäki M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Hospital, Tampere University Hospital, Tampere, Finland., Järvensivu-Koivunen M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lyytikäinen LP; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Hospital, Tampere University Hospital, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Tampere, Finland., Eskola M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Hospital, Tampere University Hospital, Tampere, Finland., Lehtimäki T; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Tampere, Finland., Nikus K; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Hospital, Tampere University Hospital, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Tampere, Finland., Oksala N; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Tampere, Finland.; Centre for Vascular Surgery and Interventional Radiology, Tampere University Hospital, Tampere, Finland., Tynkkynen J; Centre for Vascular Surgery and Interventional Radiology, Tampere University Hospital, Tampere, Finland., Hernesniemi J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Hospital, Tampere University Hospital, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Tampere, Finland.

Publikováno v: Scandinavian cardiovascular journal : SCJ [Scand Cardiovasc J] 2024 Dec; Vol. 58 (1), pp. 2335905. Date of Electronic Publication: 2024 Apr 01.