A Novel Mouse Model of Staphylococcus aureus Chronic Osteomyelitis That Closely Mimics the Human Infection: An Integrated View of Disease Pathogenesis

Autor: Horst, Sarah A., Hoerr, Verena, Beineke, Andreas, Kreis, Carolin, Tuchscherr, Lorena, Kalinka, Julia, Lehne, Sabine, Schleicher, Ina, Köhler, Gabriele, Fuchs, Thomas, Raschke, Michael J., Rohde, Manfred, Peters, Georg, Faber, Cornelius, Löffler, Bettina, Medina, Eva

Publikováno v: In The American Journal of Pathology October 2012 181(4):1206-1214

Age-related susceptibility to Streptococcus pyogenes infection in mice: underlying immune dysfunction and strategy to enhance immunity

Autor: Goldmann, Oliver, Lehne, Sabine, Medina, Eva

Epidemiological studies have shown that the elderly are at higher risk of severe Streptococcus pyogenes infections. In this study, we used a mouse model that displays the age-related loss of resistance to S. pyogenes infection seen in humans to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1146::e70264f2ddcc91ab87429a4e3d4862d0
https://hdl.handle.net/10033/98020

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Age-related susceptibility to Streptococcus pyogenes infection in mice: underlying immune dysfunction and strategy to enhance immunity.

Autor: Goldmann O; Infection Immunology Research Group, Department of Microbial Pathogenesis, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D-38124 Braunschweig, Germany., Lehne S, Medina E

Publikováno v: The Journal of pathology [J Pathol] 2010 Apr; Vol. 220 (5), pp. 521-9.