Výsledky vyhledávání - "Lehmann, Leanne"

Akademický článek

Chronic evoked seizures in young pre-symptomatic APP/PS1 mice induce serotonin changes and accelerate onset of Alzheimer’s disease-related neuropathology

Autor: del Pozo, Aaron, Knox, Kevin M., Lehmann, Leanne M., Davidson, Stephanie, Rho, Seongheon Leo, Jayadev, Suman, Barker-Haliski, Melissa

Publikováno v: In Progress in Neurobiology April 2024 235

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Can Old Animals Reveal New Targets? The Aging and Degenerating Brain as a New Precision Medicine Opportunity for Epilepsy

Autor: del Pozo, Aaron, Lehmann, Leanne, Knox, Kevin M., Barker-Haliski, Melissa

Publikováno v: Frontiers in Neurology. 13

Older people represent the fastest growing group with epilepsy diagnosis. For example, cerebrovascular disease may underlie roughly 30–50% of epilepsy in older adults and seizures are also an underrecognized comorbidity of Alzheimer's disease (AD).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c755a2098e1d95789c07d5ab1f673b07
https://doi.org/10.3389/fneur.2022.833624

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Akademický článek

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Akademický článek

DIFFERENTIAL KINDLING-INDUCED MORTALITY AND SEROTONIN PATHWAY PROTEIN EXPRESSION IN ALZHEIMER’S DISEASE-ASSOCIATED MOUSE MODELS

Autor: Knox, Kevin, Lehmann, Leanne, Davidson, Stephanie, Barker-Haliski, Melissa

Publikováno v: In IBRO Neuroscience Reports October 2023 15 Supplement 1:S390-S391

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Akademický článek

Risk of unexpected mortality is increased by evoked seizures in the APP/PSEN1, but not PSEN2‐N141I transgenic, mouse model of Alzheimer's disease.

Autor: Sanz, Aaron Del Pozo, Knox, Kevin M, Davidson, Stephanie, Lehmann, Leanne M, Barker‐Haliski, Melissa

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2022 Supplement 3, Vol. 18 Issue 3, p1-2, 2p

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Akademický článek

Presenilin 2 Knockout Mice are More Sensitive to Acute Valproic Acid in the 6 Hz Model of Focal Seizures.

Autor: Lehmann, Leanne M, Barker‐Haliski, Melissa

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2022 Supplement 3, Vol. 18 Issue 3, p1-1, 1p

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Akademický článek

Alzheimer's disease-associated genotypes differentially influence chronic evoked seizure outcomes and antiseizure medicine activity in aged mice.

Autor: Knox KM; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195., Davidson S; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195., Lehmann LM; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195., Skinner E; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195., Lo A; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195., Jayadev S; Department of Neurology, School of Medicine, University of Washington, Seattle, WA 98195., Barker-Haliski M; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 07. Date of Electronic Publication: 2024 Oct 07.

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Chronic evoked seizures in young pre-symptomatic APP/PS1 mice induce serotonin changes and accelerate onset on Alzheimer's disease-related neurpathology.

Autor: Del Pozo A, Knox KM, Lehmann L, Davidson S, Rho S, Jayadev S, Barker-Haliski M

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 31. Date of Electronic Publication: 2023 Jul 31.

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