Metabolic engineering of yeast for de novo production of kratom monoterpene indole alkaloids

Autor: Holtz, Maxence, Rago, Daniela, Nedermark, Ida, Hansson, Frederik G., Lehka, Beata J., Hansen, Lea G., Marcussen, Nils E.J., Veneman, Wouter J., Ahonen, Linda, Wungsintaweekul, Juraithip, Acevedo-Rocha, Carlos G., Dirks, Ron P., Zhang, Jie, Keasling, Jay D., Jensen, Michael K.

Publikováno v: In Metabolic Engineering November 2024 86:135-146

The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids.

Autor: Stander, Emily Amor¹ (AUTHOR), Lehka, Beata² (AUTHOR), Carqueijeiro, Inês¹ (AUTHOR), Cuello, Clément¹ (AUTHOR), Hansson, Frederik G.² (AUTHOR), Jansen, Hans J.³ (AUTHOR), Dugé De Bernonville, Thomas^1,4 (AUTHOR), Birer Williams, Caroline¹ (AUTHOR), Vergès, Valentin¹ (AUTHOR), Lezin, Enzo¹ (AUTHOR), Lorensen, Marcus Daniel Brandbjerg Bohn⁵ (AUTHOR), Dang, Thu-Thuy⁶ (AUTHOR), Oudin, Audrey¹ (AUTHOR), Lanoue, Arnaud¹ (AUTHOR), Durand, Mickael¹ (AUTHOR), Giglioli-Guivarc’h, Nathalie¹ (AUTHOR), Janfelt, Christian⁵ (AUTHOR), Papon, Nicolas⁷ (AUTHOR), Dirks, Ron P.³ (AUTHOR), O’connor, Sarah Ellen⁸ (AUTHOR) oconnor@ice.mpg.de

Publikováno v: Communications Biology. 11/23/2023, Vol. 6 Issue 1, p1-19. 19p.

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SWITCH: a dynamic CRISPR tool for genome engineering and metabolic pathway control for cell factory construction in Saccharomyces cerevisiae.

Autor: Vanegas, Katherina García¹, Lehka, Beata Joanna², Mortensen, Uffe Hasbro¹ um@bio.dtu.dk

Publikováno v: Microbial Cell Factories. 2/8/2017, Vol. 16, p1-12. 12p. 2 Diagrams, 1 Chart, 4 Graphs.