Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Legkonogov Aleksandr"'
Autor:
Gilmar Reis, Rosa Pando, Igor Kaidashev, Niaz Khasanov, Maria Christiane Valeria Braga Braile-Sternieri, Oleksii Korzh, JOSE VILELA-MARTIN, Nick West, Marco Vugman Wainstein, Massimo Volpe, Thomas Pieber, Adam Tabak, Boris Mankovsky, Vadym Berenfus, Daniel Piskorz, Legkonogov Aleksandr, Ponnusamy Saravanan, Yury Shvarts, José Gerardo González-González, Hugo Laviada, Dragan Djordjevic, Giuseppe Derosa, Juhani Airaksinen, Russell Scott, Simon Heller, Boris Vesga, Marianna Janion, SRIKANTH BELLARY, Filipa Costa, Tristan Richardson, Anthony Guimaraes, Rogério Eduardo Gomes Sarmento Leite, John Wilding, SANTIAGO TOFÉ, Konstantin Nikolaev, Bernard Van Beers, Meyer ELBAZ, Eduardo Costa Duarte Barbosa, Olga Reshetko, Milan Pavlović, Yuriy Mostovoy, Zurkurnai Yusof, Stefano Genovese, Matthew Budoff, Tudor Poerner, Andriy Bazylevych, Mirela Cleopatra Tomescu, Yuriy Sirenko, Arsen Ristic, Elena Shutemova, DAVID GALVEZ CABALLERO, Addison Taylor, Jurisic-Erzen Dubravka, Luigi Gnudi, Iurii Rudyk
Publikováno v:
New England Journal of Medicine. 369(14):1327-1335
A b s t r ac t Background To assess potentially elevated cardiovascular risk related to new antihyperglycemic drugs in patients with type 2 diabetes, regulatory agencies require a comprehensive evaluation of the cardiovascular safety profile of new a
Autor:
Gilmar Reis, Jose Nicolau, Andrzej Rynkiewicz, Simon Jones, Giovanni ESPOSITO, Konstantin Ramshev, James Spratt, Marco Vugman Wainstein, Miguel Urina, Furio Colivicchi, Legkonogov Aleksandr, Yury Shvarts, Carole Siegel, Yury Grinshtein, Diana Gorog, Ricardo Bohorquez, Alexander Joost, Aldo Pietro Maggioni, Peter Sinnaeve, Crina Julieta Sinescu, Prof. Dr. Ahmed Nahhas, Judith Hochman, Leszek Gromadziński, Catalina Arsenescu Georgescu, Mónica Jaramillo, Nattawut Wongpraparut, Filipa Costa, Yaroslav Malynovsky, Philippe Gabriel STEG, Gianluca Campo, Vladimir Zadionchenko, Andreas Zirlik, Jerome Chin, Wolfram Goessling, Daniel Pella, Roman Libis, Ivo Petrov, Giuseppe Giugliano, Glenn Hamroff, Sergei Shalaev, Amos Katz, Meyer ELBAZ, Peter Ganz, Martha Sarno, Wolfgang Koenig, ADISAI BUAKHAMSRI, Marco Valgimigli, Simcha Meisel, Svetlana Boldueva, K Srinath Reddy, FRANCISCO FUENTES JIMENEZ, Raúl J. Gazmuri, Philip Aylward, Albert Vernon Smith, Fernando Manzur, Dmitry Zateyshchikov, Zuyi Yuan, William Wijns, Arman Postadzhiyan, Arun Chopra, Andrzej Budaj, Pablo Olavegogeascoechea, Emilia Solinas
Publikováno v:
JAMA-Journal of the American Medical Association, 312(10), 1006-1015. American Medical Association
JAMA, 312(10), 1006-1015. American Medical Association
JAMA : the journal of the American Medical Association
JAMA, 312(10), 1006-1015. American Medical Association
JAMA : the journal of the American Medical Association
IMPORTANCE: Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme. OBJECTIVE: To evaluate the