Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Legh Wilkinson"'
Publikováno v:
Endocrine Connections, Vol 7, Iss 12, Pp R328-R349 (2018)
The development of resistance to glucocorticoids (GCs) in therapeutic regimens poses a major threat. Generally, GC resistance is congenital or acquired over time as a result of disease progression, prolonged GC treatment or, in some cases, both. Esse
Externí odkaz:
https://doaj.org/article/d49383a35264486ca84f60be54cafcc7
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Glucocorticoids (GCs), acting via the glucocorticoid receptor (GRα), remain the mainstay therapeutic choice for the treatment of inflammation. However, chronic GC use, aside from generating undesirable side-effects, results in GRα down-regulation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196d8b0cc951315a87d584987edd71ff
http://link.springer.com/article/10.1038/s41598-018-32440-z
http://link.springer.com/article/10.1038/s41598-018-32440-z