A quantitative model of cellular decision making in direct neuronal reprogramming.

Autor: Merlevede, Adriaan¹, Legault, Emilie M.², Drugge, Viktor¹, Barker, Roger A.³, Drouin-Ouellet, Janelle² janelle.drouin-ouellet@umontreal.ca, Olariu, Victor¹ victor.olariu@thep.lu.se

Publikováno v: Scientific Reports. 1/15/2021, Vol. 11 Issue 1, p1-18. 18p.

Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease

Autor: Vuono, Romina, Kouli, Antonina, Legault, Emilie M, Chagnon, Lauriane, Allinson, Kieren S, La Spada, Alberto, REGISTRY Investigators Of The European Huntington's Disease Network, Biunno, Ida, Barker, Roger A, Drouin-Ouellet, Janelle

BACKGROUND: Although Huntington's disease (HD) is caused by a single dominant gene, it is clear that there are genetic modifiers that may influence the age of onset and disease progression. OBJECTIVES: We sought to investigate whether new inflammatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb08a090d1fe4b8f23acc01e57345628
https://www.repository.cam.ac.uk/handle/1810/296785

Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease.

Autor: Vuono R; John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.; Medway School of Pharmacy, University of Kent at Medway, Kent, United Kingdom., Kouli A; John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Legault EM; Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada., Chagnon L; Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada., Allinson KS; Department of Pathology, Cambridge University Hospitals NHS (National Health Service) Foundation Trust, Cambridge, United Kingdom., La Spada A; Integrated Systems Engineering, Milano, Italy., Biunno I; Institute for Genetic and Biomedical Research - CNR, Milano, Italy., Barker RA; John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Drouin-Ouellet J; Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2020 Mar; Vol. 35 (3), pp. 401-408. Date of Electronic Publication: 2019 Nov 14.