Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function.

Autor: Bi W; Second Hospital of HeBei Medical University, Shijiazhuang 050000, PR China. Electronic address: biwei@hb2h.com., Bi Y; Second Hospital of HeBei Medical University, Shijiazhuang 050000, PR China., Gao X; Department of Chemistry and Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA., Li P; Second Hospital of HeBei Medical University, Shijiazhuang 050000, PR China., Hou S; Department of Chemistry and Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA., Zhang Y; Second Hospital of HeBei Medical University, Shijiazhuang 050000, PR China., Bammert C; Department of Chemistry and Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA., Jockusch S; Department of Chemistry, Columbia University, New York, NY 10027, USA., Legalley TD; Marquette General Heart and Vascular Institute, Marquette General Hospital, Marquette, MI 49855, USA., Michael Gibson K; Department of Pharmacotherapy, College of Pharmacy, Washington State University, Spokane WA 99202, USA. Electronic address: mike.gibson@wsu.edu., Bi L; Department of Chemistry and Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA. Electronic address: lanrong@mtu.edu.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2017 May 01; Vol. 25 (9), pp. 2545-2568. Date of Electronic Publication: 2017 Mar 19.

Anti-inflammatory, analgesic and antioxidant activities of novel kyotorphin-nitroxide hybrid molecules.

Autor: Bi W; Department of Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China; Second Hospital of HeBei Medical University, Shijiazhuang, HeBei 050000, PR China., Bi Y; Second Hospital of HeBei Medical University, Shijiazhuang, HeBei 050000, PR China., Gao X; Department of Chemistry, Michigan Technological University, Houghton, MI 49931, United States., Yan X; Department of Chemistry, Michigan Technological University, Houghton, MI 49931, United States., Zhang Y; Second Hospital of HeBei Medical University, Shijiazhuang, HeBei 050000, PR China., Xue P; Second Hospital of HeBei Medical University, Shijiazhuang, HeBei 050000, PR China., Bammert CE; Department of Biological Sciences, Michigan Technological University, Houghton, MI 49931, United States., Legalley TD; Marquette General Heart and Vascular Institute, Marquette, MI 49855, United States., Michael Gibson K; Section of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, WA 99202, United States., Bi L; Department of Chemistry, Michigan Technological University, Houghton, MI 49931, United States., Wang JX; Department of Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Apr 15; Vol. 26 (8), pp. 2005-13. Date of Electronic Publication: 2016 Mar 03.