Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Lefter Lp"'
Publikováno v:
ANZ Journal of Surgery. 85:420-424
Background Appendicitis is a common gastrointestinal surgical emergency. Treatment balances the risks of negative appendicectomy (NA) against potential complicated appendicitis in determining clinical priority. This study reviewed the population char
Autor:
Akira Horii, Toru Furukawa, Simona Dima, Makoto Sunamura, Yasufumi Sato, Lefter Lp, M Chivu, Irinel Popescu, Mayumi Abe
Publikováno v:
Cancer Gene Therapy. 16:137-148
In this study, we addressed the hypothesis that transcriptional suppression of erythroblastosis virus E26 oncogene homolog 1 (ETS-1) is an efficient therapeutic approach to pancreatic adenocarcinoma by investigating the effect of ETS-1 suppression in
Autor:
Shinichi Egawa, Lefter Lp, Michiaki Unno, Makoto Sunamura, Toru Furukawa, Masaharu Ishida, Masanori Akada, Rina Morita, Akira Horii
Publikováno v:
Digestive Diseases and Sciences. 53:2576-2582
Frequent loss of heterozygosity on the long arm of chromosome 18 is observed in pancreatic cancer. Previous studies suggested the existence of one or more tumor-suppressor genes other than SMAD4 on chromosome 18. To identify the candidate tumor-suppr
Autor:
Tadayoshi Abe, Makoto Sunamura, Toru Furukawa, Akira Sakurada, Akira Horii, Noriko Kotobuki, Hiroko Fujimura, Sumitaka Yamanaka, Libo Sun, Takashi Kondo, Emiko Shibuya, Mitsuo Oshimura, Toshimasa Yatsuoka, Masami Sato, Seiki Matsuno, Lefter Lp
Publikováno v:
Laboratory Investigation. 84:1339-1351
Several lines of evidence have suggested that the long arm of chromosome 12 may carry a tumor-suppressor gene(s) that plays a role in pancreatic ductal carcinogenesis. We have previously found a significant association between loss of heterozygosity
Autor:
Hiroko Inoue, Toshimasa Yatsuoka, Makoto Sunamura, Lefter Lp, Toru Furukawa, Fuyuhiko Motoi, Seiki Matsuno, Shinichi Egawa, Tadayoshi Abe, Dan G. Duda, Tadaaki Yokoyama, Akira Horii
Publikováno v:
Oncogene. 22:6857-6864
SMAD4 is a critical cofactor in signal transduction pathways activated in response to transforming growth factor-beta (TGF-beta)-related ligands, regulating cell growth and differentiation. The roles played by SMAD4 inactivation in tumours highlighte
Publikováno v:
ANZ Journal of Surgery. 78:800-802
Background: Accurate operation record keeping is an important element of risk management. Handwritten surgical notes are often produced as evidence in medico-legal malpractice cases and incomplete and illegible notes may be a source of weakness in a
Autor:
Seiki Matsuno, Hiroko Inoue, Shinichi Egawa, Toru Furukawa, Akira Horii, Mitsuo Oshimura, Toshimasa Yatsuoka, Lefter Lp, Makoto Sunamura, Tadayoshi Abe, Shinichi Fukushige, Rina Morita, Dan G. Duda, Tadaaki Yokoyama
Publikováno v:
Pancreas. 28(3)
To date, the events that mediate tumor progression in pancreatic cancer are still poorly understood. Cytogenetic, allelotype, and somatic cell hybrid studies in human pancreatic adenocarcinoma have suggested that chromosome 18 may carry tumor suppres
Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines
Autor:
Makoto Sunamura, Toru Furukawa, Akira Horii, Noriko Kotobuki, Dan G. Duda, Mitsuo Oshimura, Kazunori Takeda, Seiki Matsuno, Lefter Lp
Publikováno v:
Genes, chromosomescancer. 34(2)
A number of lines of evidence have suggested that the long arm of chromosome 18 apart from SMAD4 may carry a tumor-suppressor gene(s) that plays a role in the early stage of pancreatic ductal carcinogenesis. Thus, adenovirus-mediated introduction of
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Akademický článek
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