Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Leffler EM"'
Autor:
Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Gonçalves, S, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, d'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Saelens, JW, Diakité, M, Taylor, SM, Conway, DJ, Rockett, KA, Kwiatkowski, DP, Williams, TN
Publikováno v:
Nature. 602:106-111
Host genetic factors can confer resistance against malaria1, raising the question of whether this has led to evolutionary adaptation of parasite populations. Here we searched for association between candidate host and parasite genetic variants in 3,3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b1c4fd1ae5564e278163ce1191f794
https://doi.org/10.1038/s41586-021-04288-3
https://doi.org/10.1038/s41586-021-04288-3
Autor:
Band G; Centre for Human Genetics, University of Oxford, Oxford, UK., Leffler EM; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: leffler@genetics.utah.edu.
Publikováno v:
Trends in parasitology [Trends Parasitol] 2024 Aug; Vol. 40 (8), pp. 660-661. Date of Electronic Publication: 2024 Jul 15.
Autor:
Haffener PE; Department of Human Genetics, The University of Utah School of Medicine, Salt Lake City, UT, USA., Al-Riyami AZ; Department of Hematology, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman., Al-Zadjali S; Sultan Qaboos Comprehensive Cancer Center, University Medical City, Muscat, Oman., Al-Rawahi M; Department of Hematology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Al Hosni S; Department of Hematology, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman., Al Marhoobi A; Department of Hematology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Al Sheriyani A; Royal Oman Police Hospital, Muscat, Oman., Leffler EM; Department of Human Genetics, The University of Utah School of Medicine, Salt Lake City, UT, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 18. Date of Electronic Publication: 2024 Jun 18.
Autor:
Hilbert ZA; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Haffener PE; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA., Young HJ; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Schwiesow MJW; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Leffler EM; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA., Elde NC; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Publikováno v:
Genome biology and evolution [Genome Biol Evol] 2023 Jul 03; Vol. 15 (7).
Autor:
Band G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. gavin.band@well.ox.ac.uk.; Wellcome Sanger Institute, Hinxton, Cambridge, UK. gavin.band@well.ox.ac.uk.; Big Data Institute, Li Ka Shing Centre for Health and Information Discovery, University of Oxford, Oxford, UK. gavin.band@well.ox.ac.uk., Leffler EM; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA., Jallow M; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Edward Francis Small Teaching Hospital (formerly Royal Victoria Teaching Hospital), Banjul, The Gambia., Sisay-Joof F; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Ndila CM; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Macharia AW; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Hubbart C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Jeffreys AE; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Rowlands K; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Nguyen T; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Gonçalves S; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Ariani CV; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Stalker J; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Pearson RD; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Big Data Institute, Li Ka Shing Centre for Health and Information Discovery, University of Oxford, Oxford, UK., Amato R; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Drury E; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Sirugo G; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Division of Translational Medicine and Human Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., d'Alessandro U; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Bojang KA; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia., Marsh K; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Peshu N; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Saelens JW; Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA., Diakité M; Malaria Research and Training Center, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali., Taylor SM; Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA.; Duke Global Health Institute, Duke University, Durham, NC, USA., Conway DJ; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Williams TN; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.; Institute for Global Health Innovation, Department of Surgery and Cancer, Imperial College London, London, UK., Rockett KA; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. kirk.rockett@well.ox.ac.uk.; Wellcome Sanger Institute, Hinxton, Cambridge, UK. kirk.rockett@well.ox.ac.uk., Kwiatkowski DP; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. dominic@sanger.ac.uk.; Wellcome Sanger Institute, Hinxton, Cambridge, UK. dominic@sanger.ac.uk.; Big Data Institute, Li Ka Shing Centre for Health and Information Discovery, University of Oxford, Oxford, UK. dominic@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2022 Feb; Vol. 602 (7895), pp. 106-111. Date of Electronic Publication: 2021 Dec 09.
Autor:
Amuzu DS; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Rockett KA; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Sanger Institute, Hinxton CB10 1SA, UK., Leffler EM; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112-5330, USA., Ansah F; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana., Amoako N; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana., Morang'a CM; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana., Hubbart C; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Rowlands K; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Jeffreys AE; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Amenga-Etego LN; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana., Kwiatkowski DP; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Awandare GA; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, GH 0233, Ghana.; Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, GH 0233, Ghana.
Publikováno v:
Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2021 Apr; Vol. 246 (8), pp. 916-928. Date of Electronic Publication: 2020 Dec 16.
Autor:
Leffler EM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK, and the Wellcome Trust Sanger Institute, Hinxton, UK.
Publikováno v:
Nature genetics [Nat Genet] 2017 Nov 29; Vol. 49 (12), pp. 1671-1672.
Autor:
Leffler EM; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Band G; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Busby GBJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Kivinen K; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Le QS; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Clarke GM; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Bojang KA; Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia., Conway DJ; Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia.; Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK., Jallow M; Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia.; Royal Victoria Teaching Hospital, Independence Drive, Post Office Box 1515, Banjul, The Gambia., Sisay-Joof F; Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia., Bougouma EC; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 2208 Ouagadougou 01, Burkina Faso., Mangano VD; University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy., Modiano D; University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy., Sirima SB; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 2208 Ouagadougou 01, Burkina Faso., Achidi E; Department of Medical Laboratory Sciences, University of Buea, Post Office Box 63, Buea, South West Region, Cameroon., Apinjoh TO; Department of Biochemistry and Molecular Biology, University of Buea, Post Office Box 63, Buea, South West Region, Cameroon., Marsh K; Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya.; Nuffield Department of Medicine, NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, UK., Ndila CM; Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya., Peshu N; Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya., Williams TN; Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya.; Faculty of Medicine, Department of Medicine, Imperial College, Exhibition Road, London SW7 2AZ, UK., Drakeley C; Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Post Office Box 2228, Moshi, Tanzania.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK., Manjurano A; Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Post Office Box 2228, Moshi, Tanzania.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.; National Institute for Medical Research, Mwanza Research Centre, Mwanza City, Tanzania., Reyburn H; Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Post Office Box 2228, Moshi, Tanzania.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK., Riley E; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK., Kachala D; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi., Molyneux M; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi.; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK., Nyirongo V; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi., Taylor T; Blantyre Malaria Project, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi.; College of Osteopathic Medicine, Michigan State University, East Lansing, MI 48824, USA., Thornton N; International Blood Group Reference Laboratory, National Health Service (NHS) Blood and Transplant, 500 North Bristol Park, Filton, Bristol BS34 7QH, UK., Tilley L; International Blood Group Reference Laboratory, National Health Service (NHS) Blood and Transplant, 500 North Bristol Park, Filton, Bristol BS34 7QH, UK., Grimsley S; International Blood Group Reference Laboratory, National Health Service (NHS) Blood and Transplant, 500 North Bristol Park, Filton, Bristol BS34 7QH, UK., Drury E; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Stalker J; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Cornelius V; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Hubbart C; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Jeffreys AE; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Rowlands K; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Rockett KA; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Spencer CCA; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. chris.spencer@well.ox.ac.uk dominic.kwiatkowski@sanger.ac.uk., Kwiatkowski DP; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. chris.spencer@well.ox.ac.uk dominic.kwiatkowski@sanger.ac.uk.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Publikováno v:
Science (New York, N.Y.) [Science] 2017 Jun 16; Vol. 356 (6343). Date of Electronic Publication: 2017 May 18.
Autor:
Singhal S; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Department of Systems Biology, Columbia University, New York, NY 10032, USA. sonal.singhal1@gmail.com molly.przew@gmail.com., Leffler EM; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Sannareddy K; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA., Turner I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Venn O; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Hooper DM; Committee on Evolutionary Biology, University of Chicago, Chicago, IL 60637, USA., Strand AI; Department of Biological Sciences, Columbia University, New York, NY 10027, USA., Li Q; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China., Raney B; Center for Biomolecular Science and Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA., Balakrishnan CN; Department of Biology, East Carolina University, Greenville, NC 27858, USA., Griffith SC; Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia., McVean G; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Przeworski M; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Department of Systems Biology, Columbia University, New York, NY 10032, USA. sonal.singhal1@gmail.com molly.przew@gmail.com.
Publikováno v:
Science (New York, N.Y.) [Science] 2015 Nov 20; Vol. 350 (6263), pp. 928-32.
Autor:
Leffler EM; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA. emleffler@uchicago.edu, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M
Publikováno v:
Science (New York, N.Y.) [Science] 2013 Mar 29; Vol. 339 (6127), pp. 1578-82. Date of Electronic Publication: 2013 Feb 14.