Exploring the Efficacy of Pembrolizumab in Combination with Carboplatin and Weekly Paclitaxel for Frail Patients with Advanced Non-Small-Cell Lung Cancer: A Key Investigative Study.

Autor: Thomas QD; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France.; Oncogenic Pathways in Lung Cancer, Montpellier Cancer Research Institute (IRCM) INSERM U1194, University of Montpellier (UM), 34090 Montpellier, France., Chaabouni M; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France., Al Herk A; Biometrics Unit ICM, Montpellier Cancer Institute, University of Montpellier (UM), 34090 Montpellier, France., Lefevbre C; Pharmacy Department, Montpellier Cancer Institute (ICM), 34090 Montpellier, France., Cavaillon S; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France., Sinoquet L; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France., Pouderoux S; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France., Viala M; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France., Roca L; Biometrics Unit ICM, Montpellier Cancer Institute, University of Montpellier (UM), 34090 Montpellier, France., Quantin X; Department of Medical Oncology, Montpellier Cancer Institute (ICM), University of Montpellier (UM), 34090 Montpellier, France.; Oncogenic Pathways in Lung Cancer, Montpellier Cancer Research Institute (IRCM) INSERM U1194, University of Montpellier (UM), 34090 Montpellier, France.

Publikováno v: Cancers [Cancers (Basel)] 2024 Feb 29; Vol. 16 (5). Date of Electronic Publication: 2024 Feb 29.

SET domain containing protein 8 (SET8) promotes tumour progression and indicates poor prognosis in patients with laryngeal squamous cell carcinoma.

Autor: Li-Li Lan¹, Sheng-Hui Liu¹, Zhi-Tao Fan², Xue-Xia Wang², Jing-Tian Wang¹, Ke-Xin Wang¹, Rui-Li Zhao³ Zhaorl0101@163.com

Publikováno v: Oncologie (De Gruyter). Jan2023, Vol. 25 Issue 1, p61-69. 9p.

Roles for the methyltransferase SETD8 in DNA damage repair.

Autor: Xu, Libo^1,2 (AUTHOR), Zhang, Ling^1,2 (AUTHOR), Sun, Jicheng¹ (AUTHOR), Hu, Xindan¹ (AUTHOR), Kalvakolanu, Dhan V.³ (AUTHOR), Ren, Hui¹ (AUTHOR) hren@jlu.edu.cn, Guo, Baofeng¹ (AUTHOR) gbf@jlu.edu.cn

Publikováno v: Clinical Epigenetics. 3/4/2022, Vol. 14 Issue 1, p1-14. 14p.

Beyond the tail: the consequence of context in histone post-translational modification and chromatin research.

Autor: Weinzapfel, Ellen N., Fedder-Semmes, Karlie N., Zu-Wen Sun, Keogh, Michael-Christopher

Publikováno v: Biochemical Journal; 2/15/2024, Vol. 481 Issue 4, p219-244, 26p

CRL4^Cdt2 ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation.

Autor: Zhang, Jia-Min¹ (AUTHOR), Zheng, Jin-Xin¹ (AUTHOR), Ding, Yue-He¹ (AUTHOR), Zhang, Xiao-Ran¹ (AUTHOR), Suo, Fang¹ (AUTHOR), Ren, Jing-Yi¹ (AUTHOR), Dong, Meng-Qiu^1,2 (AUTHOR), Du, Li-Lin^1,2 (AUTHOR) dulilin@nibs.ac.cn

Publikováno v: PLoS Genetics. 7/21/2020, Vol. 16 Issue 7, p1-21. 21p.