Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap.

Autor: Hedison TM; Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester , Manchester M1 7DN, United Kingdom., Leferink NG; Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester , Manchester M1 7DN, United Kingdom., Hay S; Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester , Manchester M1 7DN, United Kingdom., Scrutton NS; Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester , Manchester M1 7DN, United Kingdom.

Publikováno v: ACS catalysis [ACS Catal] 2016 Aug 05; Vol. 6 (8), pp. 5170-5180. Date of Electronic Publication: 2016 Jun 28.

Impact of residues remote from the catalytic centre on enzyme catalysis of copper nitrite reductase.

Autor: Leferink NG; 1] Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK [2]., Antonyuk SV; 1] Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK [2]., Houwman JA; Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK., Scrutton NS; Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK., Eady RR; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Hasnain SS; Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.

Publikováno v: Nature communications [Nat Commun] 2014 Jul 15; Vol. 5, pp. 4395. Date of Electronic Publication: 2014 Jul 15.

Communication between (L)-galactono-1,4-lactone dehydrogenase and cytochrome c.

Autor: Hervás M; Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC and University of Sevilla, Spain., Bashir Q, Leferink NG, Ferreira P, Moreno-Beltrán B, Westphal AH, Díaz-Moreno I, Medina M, de la Rosa MA, Ubbink M, Navarro JA, van Berkel WJ

Publikováno v: The FEBS journal [FEBS J] 2013 Apr; Vol. 280 (8), pp. 1830-40. Date of Electronic Publication: 2013 Mar 25.

Gating mechanisms for biological electron transfer: integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase.

Autor: Leferink NG; Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom., Pudney CR, Brenner S, Heyes DJ, Eady RR, Samar Hasnain S, Hay S, Rigby SE, Scrutton NS

Publikováno v: FEBS letters [FEBS Lett] 2012 Mar 09; Vol. 586 (5), pp. 578-84. Date of Electronic Publication: 2011 Jul 14.

Galactonolactone oxidoreductase from Trypanosoma cruzi employs a FAD cofactor for the synthesis of vitamin C.

Autor: Kudryashova EV; Wagenigen University, Wagenigen, The Netherlands., Leferink NG, Slot IG, van Berkel WJ

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2011 May; Vol. 1814 (5), pp. 545-52. Date of Electronic Publication: 2011 Mar 21.