Výsledky vyhledávání - "Lef Zografos"

Afatinib versus methotrexate as second-line treatment for patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) progressing on or after platinum-based therapy: LUX-Head & Neck 3 phase III trial

Autor: Xiaohui He, Rajendra Singh Arora, Jin Hyoung Kang, Ye Guo, Cheng-Hsu Wang, Myung-Ju Ahn, Ezra E.W. Cohen, Yuan Geng, P. Li, Krishna M. Kamble, Lef Zografos, Qingyuan Zhang, Maximino De Guzman Bello, Ping Zhang Tang, Alaa Kandil, Vijay Kumar, Sung-Bae Kim, Arunee Dechaphunkul, Wei Li, Anthony T.C. Chan

Publikováno v: Journal of Clinical Oncology. 37:6024-6024

6024 Background: In a previous global phase III trial (LUX-Head & Neck 1), second-line (2L) afatinib significantly improved PFS vs methotrexate (MTX) in pts with R/M HNSCC. Here, we compared efficacy/safety of 2L afatinib vs MTX in Asian pts with R/M

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