Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leeor Zilbermintz"'
Autor:
Robert W. B. Brown, Aabha I. Sharma, Miguel Rey Villanueva, Xiaomo Li, Ouma Onguka, Leeor Zilbermintz, Helen Nguyen, Ben A. Falk, Cheryl L. Olson, Joann M. Taylor, Conrad L. Epting, Rahul S. Kathayat, Neri Amara, Bryan C. Dickinson, Matthew Bogyo, David M. Engman
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1245 (2022)
Dynamic post-translational modifications allow the rapid, specific, and tunable regulation of protein functions in eukaryotic cells. S-acylation is the only reversible lipid modification of proteins, in which a fatty acid, usually palmitate, is coval
Externí odkaz:
https://doaj.org/article/6c387e0ab88c4cb1a07423163734940f
Autor:
Christopher K. Cote, Jennifer E. Peel, Samandra T. Demons, Jennifer K Tran, Lynda L. Miller, Chi-Lee C. Ho, Satheesh K Sivasubramani, Chiu-Yen Kao, Jennifer L. Shoe, David P Fetterer, Mikhail Martchenko Shilman, Johnny W. Peterson, Gloria Bartolo, Ryan C. McComb, Saleem Alameh, Kenneth A. Bradley, David W.C. Beasley, Stella Hartmann, Emiene Amali-Adekwu, William S Lawrence, Anastasia Levitin, Marina Chugunova, Joel West, Leeor Zilbermintz, Christopher P. Klimko, Luisa W. Cheng, Aram Derbedrossian, Stephanie A Halasahoris
Publikováno v:
ACS Infect Dis
[Image: see text] Anthrax is caused by Bacillus anthracis and can result in nearly 100% mortality due in part to anthrax toxin. Antimalarial amodiaquine (AQ) acts as a host-oriented inhibitor of anthrax toxin endocytosis. Here, we determined the phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df80135ee02f50492e189d514256fed9
https://doi.org/10.1021/acsinfecdis.1c00190
https://doi.org/10.1021/acsinfecdis.1c00190
Autor:
Jeffrey H. Elliott, Rouzbeh Zamani, Farooq Nasar, Sina Bavari, Sharon H. Tran, Mikhail Martchenko, Leeor Zilbermintz, William Leonardi, Xiaoli Chi, Anastasia Levitin, Veronica Soloveva, Dima N. Gharaibeh, Michael C. Bassik, Robert Manasherob, Stanley N. Cohen, Josue Zozaya, Tara Kenny, Luisa W. Cheng, Andrew D. Haddow, Kseniya Polukhina, Amy Li
Publikováno v:
Scientific Reports
Diverse pathogenic agents often utilize overlapping host networks and hub proteins within these networks represent attractive targets for broad-spectrum drugs. Using bacterial toxins, we describe a new approach for discovering broad-spectrum therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b844fd946b94bb3faa228b6b190aa7
https://doi.org/10.1038/srep34475
https://doi.org/10.1038/srep34475
Autor:
Sun-Young Jeong, Rouzbeh Zamani, Robert T. Clubb, Sina Bavari, Mikhail Martchenko, Kenneth A. Bradley, William Leonardi, Leeor Zilbermintz, Joel West, Veronica Soloveva, Vivek Gupta, Dima N. Gharaibeh, Anastasia Levitin, Chi-Lee C. Ho, Cary Retterer, Megan Sjodt, Stanley N. Cohen, Ryan C. McComb
Publikováno v:
Scientific Reports
A longstanding and still-increasing threat to the effective treatment of infectious diseases is resistance to antimicrobial countermeasures. Potentially, the targeting of host proteins and pathways essential for the detrimental effects of pathogens o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf7bbfc768fac0aa887723ebb3b19f9
https://pubmed.ncbi.nlm.nih.gov/26310922
https://pubmed.ncbi.nlm.nih.gov/26310922
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials
Background The high cost and prolonged timeline of new drug discovery and development are major roadblocks to creating therapies for infectious diseases. Candida albicans is an opportunistic fungal pathogen that is the most common cause of fatal fung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe1fded934b0528f2ab9807f5e49e81
https://pubmed.ncbi.nlm.nih.gov/26054754
https://pubmed.ncbi.nlm.nih.gov/26054754