Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leendert Hj, Looijenga"'
Autor:
Yolande van Bever, Ruben G Boers, Hennie T Brüggenwirth, Wilfred Fj van IJcken, Frank J Magielsen, Annelies de Klein, Joachim B Boers, Leendert Hj Looijenga, Erwin Brosens, Joost Gribnau, Sabine E Hannema
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
In patients with proximal hypospadias, often no genetic cause is identified despite extensive genetic testing. Many genes involved in sex development encode transcription factors with strict timing and dosing of the gene products. We hypothesised tha
Externí odkaz:
https://doaj.org/article/71fec12029654280bacf538ebc935943
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 3, Pp 381-393 (2015)
Malignant testicular germ cell tumors (TGCT) are the most frequent cancers in Caucasian males (20-40 years) with an 70% increasing incidence the last 20 years, probably due to combined action of (epi)genetic and (micro)environmental factors. It is ex
Externí odkaz:
https://doaj.org/article/9967700a9e024cc39d8ca0c1b05d409b
Autor:
Martine, Cools, Leendert Hj, Looijenga
Publikováno v:
Pediatric endocrinology reviews : PER. 9
A subset of patients with disorders of sex development (DSD) is at risk for malignant germ cell tumors (GCTs). The degree of gonadal differentiation (or "testicularization" in the presence of a specific part of the Y chromosome), in combination with
Autor:
Leendert Hj Looijenga
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Germ cell tumours comprise a heterogeneous group of neoplasms, which can be found at different, although restricted anatomical locations. In the testis three groups of germ cell-derived tumours are distinguished: Iteratomas and yolk sac tumours of in