Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Leena P Bharath"'
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Externí odkaz:
https://doaj.org/article/7dbaae1fcf05484ea7433d002ba7b86f
Autor:
Laura Haynes, Leena P. Bharath
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Externí odkaz:
https://doaj.org/article/b423224c9c814afd9d48cf89ab6f92ab
Autor:
Rachel Conway, Jack Donato Rockhold, Sara SantaCruz-Calvo, Emelia Zukowski, Gabriella H. Pugh, Hatice Hasturk, Philip A. Kern, Barbara S. Nikolajczyk, Leena P. Bharath
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Obesity promotes the onset and progression of metabolic and inflammatory diseases such as type 2 diabetes. The chronic low-grade inflammation that occurs during obesity triggers multiple signaling mechanisms that negatively affect organismal health.
Externí odkaz:
https://doaj.org/article/3aab8723ae97408e900f326d92f5129e
Publikováno v:
Cells, Vol 10, Iss 8, p 2114 (2021)
Dysregulation of autophagy is an important underlying cause in the onset and progression of many metabolic diseases, including diabetes. Studies in animal models and humans show that impairment in the removal and the recycling of organelles, in parti
Externí odkaz:
https://doaj.org/article/171856612af04093b0d462b5d9f7101d
Publikováno v:
Clinical and Experimental Hypertension, Vol 39, Iss 6, Pp 546-552 (2017)
Childhood obesity is strongly linked to pathological processes for cardiovascular diseases in later adulthood. Obese adolescent girls with high blood pressure (BP) are reported to have increased arterial stiffness, which is associated with the develo
Externí odkaz:
https://doaj.org/article/569a66df5e204994ad279662033263f7
Publikováno v:
Am J Physiol Cell Physiol
Redox homeostasis is elemental for the normal physiology of all cell types. Cells use multiple mechanisms to tightly regulate the redox balance. The onset and progression of many metabolic and aging-associated diseases occur due to the dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc74ecaef47ad12c7ccc42e36b2b2239
https://pubmed.ncbi.nlm.nih.gov/35938879
https://pubmed.ncbi.nlm.nih.gov/35938879
Autor:
Jae Min Cho, Seul-Ki Park, Oh Sung Kwon, David Taylor La Salle, James Cerbie, Caitlin C Fermoyle, David Morgan, Ashley Nelson, Amber Bledsoe, Leena P Bharath, Megan Tandar, Satya P Kunapuli, Russell S Richardson, Pon Velayutham Anandh Babu, Sohom Mookherjee, Bellamkonda K Kishore, Fei Wang, Tianxin Yang, Sihem Boudina, Joel D Trinity, John David Symons
Publikováno v:
Cardiovasc Res
Aim The importance of endothelial cell (EC) autophagy to vascular homeostasis in the context of health and disease is evolving. Earlier, we reported that intact EC autophagy is requisite to maintain shear-stress-induced nitric oxide (NO) generation v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd999d10c4749f301b8aea2cac7d1c2
https://doi.org/10.1093/cvr/cvac061
https://doi.org/10.1093/cvr/cvac061
Publikováno v:
International Journal of Phytoremediation. 24:12-24
Silver nanoparticles (AgNPs) are particularly among the widely used nanomaterials in medicine, industry, and agriculture. The small size and large surface area of AgNPs and other nanomaterials result in their high reactivity in biological systems. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777c97fe350ff791d4f615dc6b01a815
https://doi.org/10.1080/15226514.2021.1919052
https://doi.org/10.1080/15226514.2021.1919052
Publikováno v:
Biomolecules, Vol 9, Iss 8, p 298 (2019)
Elesclomol ((N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)); formerly STA-4783) is a mitochondria-targeted chemotherapeutic agent that has demonstrated efficacy in selective cancer cell killing in pre-clinical and clinical testing. The biologi
Externí odkaz:
https://doaj.org/article/b29460ae9fa243c3821dab44e6168542
Autor:
Grace McCambridge, Madhur Agrawal, Alanna Keady, Philip A. Kern, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath
Publikováno v:
Biomolecules, Vol 9, Iss 2, p 79 (2019)
Circulating fatty acids (FAs) increase with obesity and can drive mitochondrial damage and inflammation. Nicotinamide nucleotide transhydrogenase (NNT) is a mitochondrial protein that positively regulates nicotinamide adenine dinucleotide phosphate (
Externí odkaz:
https://doaj.org/article/fb911753e26545418386520413d3194a