Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leena Laurén"'
Autor:
Ritva Hannuniemi, Z. Peng, Leena Laurén, K. Kippo, H. Kalervo Väänänen, Sellman Raija, Päivi Isaksson, Thua Österman, Juha Tuukkanen, Pirjo Kuurtamo
Publikováno v:
Journal of Bone and Mineral Research. 13:287-296
Daily oral clodronate treatment was evaluated in Sprague-Dawley rats for its ability to inhibit estrogen-deficiency-induced changes in femoral neck, femoral diaphysis, and lumbar vertebrae (L4-L5). Six-month-old ovariectomized (OVX) rats were adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0d884b03cb58db2c1fc8763d98a04f
https://doi.org/10.1359/jbmr.1998.13.2.287
https://doi.org/10.1359/jbmr.1998.13.2.287
Autor:
Thua Österman, Leena Laurén
Publikováno v:
Pharmacology & Toxicology. 69:369-371
The levels of clodronate in bone and plasma were determined in rats after subcutaneous injection of a mixture of unlabelled and 14C-labelled disodium clodronate as a single dose (25 mg/5 muCi/kg or of 125 mg/25 muCi/kg), and as repeated doses (25 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1babb75ed33c0530ea7a7c87141cfdde
https://doi.org/10.1111/j.1600-0773.1991.tb01313.x
https://doi.org/10.1111/j.1600-0773.1991.tb01313.x
Publikováno v:
Pharmacologytoxicology. 74(4-5)
The effect of iron on the absorption and distribution of disodium clodronate in rats after oral administration was studied. Disodium clodronate (300 mg/25 microCi/kg) was given both alone and with an equivalent amount of ferrous sulphate. The radioac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f34b0037c400397c58a73f245ca091
https://pubmed.ncbi.nlm.nih.gov/8090698
https://pubmed.ncbi.nlm.nih.gov/8090698
Publikováno v:
Pharmacologytoxicology. 69(5)
The pharmacokinetics of clodronate was studied in rats after single intravenous, intramuscular and subcutaneous doses of a mixture of unlabelled and 14C-labelled disodium clodronate (25 mg/5 muCi/kg). The peak clodronate concentration in plasma was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e46bcbc32ce06cdce8df14324e03e9
https://pubmed.ncbi.nlm.nih.gov/1839447
https://pubmed.ncbi.nlm.nih.gov/1839447