Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Leena Kivipelto"'
Autor:
Anna-Pauliina Iivonen, Johanna Känsäkoski, Atte Karppinen, Leena Kivipelto, Camilla Schalin-Jäntti, Auli Karhu, Taneli Raivio
Publikováno v:
Endocrine Connections, Vol 7, Iss 5, Pp 645-652 (2018)
Objective: Recently, mutations in KCNQ1, a potassium channel gene usually linked to long QT syndrome, were reported to cause maternally inherited gingival fibromatosis and growth hormone deficiency (GHD). Expression of the mutated KCNQ1 with the auxi
Externí odkaz:
https://doaj.org/article/aa93e0b0dcf3468692f67109c86580d3
Autor:
Hande Demir, Iikki Donner, Leena Kivipelto, Outi Kuismin, Camilla Schalin-Jäntti, Ernesto De Menis, Auli Karhu
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109897 (2014)
Pituitary adenomas are neoplasms of the anterior pituitary lobe and account for 15-20% of all intracranial tumors. Although most pituitary tumors are benign they can cause severe symptoms related to tumor size as well as hypopituitarism and/or hypers
Externí odkaz:
https://doaj.org/article/d070a9297e854165afde32fb57a2f599
Autor:
Auli Karhu, Lauri A. Aaltonen, Leena Kivipelto, Anders Paetau, Atte Karppinen, Camilla Schalin-Jäntti, Niko Välimäki
Supplementary Figures S4-5 show 4) Total- and phsoporylated-RB1 inmmunohostochemistry in CA- and CS-tumors. 5) PTPR and PTPRK immunohistochemistry in CA- and CS-tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be376835bf83a167dd3dd67d91c7774
https://doi.org/10.1158/1541-7786.22516099
https://doi.org/10.1158/1541-7786.22516099
Autor:
Auli Karhu, Lauri A. Aaltonen, Leena Kivipelto, Anders Paetau, Atte Karppinen, Camilla Schalin-Jäntti, Niko Välimäki
Supplementary Methods text containing details about mutation status validation of established pituitary adenoma predisposing genes and IHC scoring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341f1ba82b7cb1ce64ce5247dd8ec731
https://doi.org/10.1158/1541-7786.22516090
https://doi.org/10.1158/1541-7786.22516090
Autor:
Auli Karhu, Lauri A. Aaltonen, Leena Kivipelto, Anders Paetau, Atte Karppinen, Camilla Schalin-Jäntti, Niko Välimäki
Supplementary Figure S6 shows Ki-67- and PTTG1 immunostainings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911675fb3ae74c8a6f22d9e90a32d2aa
https://doi.org/10.1158/1541-7786.22516105
https://doi.org/10.1158/1541-7786.22516105
Autor:
Auli Karhu, Lauri A. Aaltonen, Leena Kivipelto, Anders Paetau, Atte Karppinen, Camilla Schalin-Jäntti, Niko Välimäki
Supplementary Tables S1-S10 shows: 1) All the coding region variants (missense, premature stop codon, frameshift) of 21 sequenced somatotropinomas that passed the somatic filtering. 2) Results of correlation tests between genetic instability (GI%) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105997987c8bf420ec1392756d4786f
https://doi.org/10.1158/1541-7786.22516087.v1
https://doi.org/10.1158/1541-7786.22516087.v1
Autor:
Auli Karhu, Lauri A. Aaltonen, Leena Kivipelto, Anders Paetau, Atte Karppinen, Camilla Schalin-Jäntti, Niko Välimäki
Somatic driver mechanisms of pituitary adenoma pathogenesis have remained incompletely characterized; apart from mutations in the stimulatory Gα protein (Gαs encoded by GNAS) causing activated cAMP synthesis, pathogenic variants are rarely found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ba657eed75abbacd5bd1d3eef03261
https://doi.org/10.1158/1541-7786.c.6541276
https://doi.org/10.1158/1541-7786.c.6541276
Autor:
Leena Kivipelto, Juha Hernesniemi, Erja Poutiainen, Sanni Ruotsalainen, Anna-Maria Uusitalo, Johanna Pekkola, Marika Savolainen, Satu Mustanoja, Tiina Tyni, Turgut Tatlisumak
Publikováno v:
Journal of Neurology
Background and purpose Moyamoya angiopathy (MMA) is a chronic cerebrovascular disorder predominantly starting in childhood or early adulthood and thus affects the whole lifetime. Little is known on MMAs long-term outcomes in European patients. We rep
Autor:
Juha Hernesniemi, Turgut Tatlisumak, Leena Kivipelto, Tiina Tyni, Marika Savolainen, Satu Mustanoja, Johanna Pekkola
Publikováno v:
Journal of Neurology
Background and purpose Moyamoya angiopathy (MMA) is a chronic progressive disorder, but imaging changes observed over time are not yet characterized in European populations. We analyzed the progression of MMA with magnetic resonance imaging and angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1116086bab26f503c4e68cd8d951d464
http://hdl.handle.net/10138/318527
http://hdl.handle.net/10138/318527
Autor:
Niko Välimäki, Leena Kivipelto, Auli Karhu, Anders Paetau, Atte Karppinen, Lauri A. Aaltonen, Camilla Schalin-Jäntti
Somatic driver mechanisms of pituitary adenoma pathogenesis have remained incompletely characterized; apart from mutations in the stimulatory Gα protein (Gαs encoded by GNAS) causing activated cAMP synthesis, pathogenic variants are rarely found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bbc08f5286de777d37cdfadaa86960
http://hdl.handle.net/10138/323526
http://hdl.handle.net/10138/323526