Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Leena Khare Satyam"'
Autor:
Lakshmi Narayan Kaza, Thomas Anthony, Sunil Kumar Pnaigrahi, Aditya Kiran Gatta, Kiran Aithal, Pravin Pise, Vijay Kamal Ahuja, Narasimha Rao Krishnamurthy, Sanjeev Giri, Vinayak Khairnar, Narasimha Raju Kalidindi, Murali Ramachandra, KB Charamannna, Nirbhay Kumar Tiwari, Susanta Samajdar, Vijaya Shankar Nataraj, Dinesh Chikkanna, Shekar Chelur, Kavitha Nellore, Manoj Pothuganti, Sandeep Patil, DS Samiulla, Leena Khare Satyam
Publikováno v:
Cancer Research. 81:1266-1266
Dysregulated fatty acid metabolism is thought to be a hallmark of cancer, wherein fatty acids function both as an energy source and as signals for enzymatic and transcriptional networks contributing to malignancy. Fatty acid-binding protein 5 (FABP5)
Autor:
Subhendu Mukherjee, Susanta Samajdar, Sandeep Vitthal Dukare, Murali Ramachandra, Girish Daginakatte, Sanjeev Giri, Chandrasekhar Abbineni, M. R Sreevidya, Vijay Kamal Ahuja, Kiran Aithal, Charamanna Kb, Thomas Antony, DS Samiulla, Rakesh P. Nankar, Khaji Abdul Rawoof, Megha Goyal, Leena Khare Satyam, Suraj T. Gore, Bilash Kuila, Shekar Chelur, Ashok Ettam, Kavitha Nellore
Publikováno v:
Cancer Research. 81:1144-1144
Background: SMARCA2 (BRM) and SMARCA4 (BRG1) are two mutually exclusive DNA-dependent ATPases of the SWI/SNF complex, which function in mobilizing nucleosomes to regulate transcription, DNA replication/repair and chromosome dynamics. SMARCA4 is known
Autor:
N.K. Tiwari, Shekar Chelur, S. Thiyagarajan, Girish Daginakatte, Murali Ramachandra, K. Charamanna, A. Aravind, T. Devaraja, S. Giri, R. Booher, Lakshmi Narayana Kaza, Subhendu Mukherjee, DS Samiulla, Leena Khare Satyam, A.A. Dhudashiya, T. Antony, S. Samajdar, Ramulu Poddutoori, Sivapriya Marappan, K. Nellore
Publikováno v:
European Journal of Cancer. 138:S47
Autor:
Jaya Nigam, Balraj Mittal, Annapurna Gupta, Meenu Srivastava, Leena Khare Satyam, Hasan Raza Kazmi, Saket Kumar, Abhijit Chandra
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 142:2577-2583
Gallbladder cancer is a lethal malignancy of hepato-biliary system with high incidence in North India, especially along gangetic plain. The let-7 microRNAs play a key role in regulating KRAS expression and a polymorphism in 3′ untranslated region (
Autor:
Nagaraj Gowda, Sureshkumar Vadlamani, Amit A. Dhudashiya, Rajeev K. Shrimali, Rashmi Nair, Leena Khare Satyam, Murali Ramachandra, Sreenivas Adurthi, Krishnaprasad Subbarao, Sriharibabu Vunnum, Raghuveer Ramachandra, Koteswararao Vemula, Dodderi S. Samiulla, Pottayil G. Sasikumar
Publikováno v:
Molecular cancer therapeutics. 18(6)
Pioneering success of antibodies targeting immune checkpoints such as PD-1 and CTLA4 has opened novel avenues for cancer immunotherapy. Along with impressive clinical activity, severe immune-related adverse events (irAE) due to the breaking of immune
Autor:
Rajeev Goswami, Subhendu Mukherjee, Gerd Wohlfahrt, Jwala Nagaraj, Krishnaprasad Subbarao, Chakshusmathi Ghadiyaram, Narasimha Rao Krishnamurthy, Leena Khare Satyam, Sreevalsam Gopinath, Hosahalli Subramanya, Murali Ramachandra
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:616-620
Matriptase is a cell-surface trypsin-like serine protease of epithelial origin, which cleaves and activates proteins including hepatocyte growth factor/scatter factor and proteases such as uPA, which are involved in the progression of various cancers
Autor:
Ashokk Ettam, Shankaraiah Chithaluru, Charamanna Kb, DS Samiulla, Murali Ramachandra, Amitkumar A. Pawar, Rakesh P. Nankar, M. R Sreevidya, Nagesh Gowda S, Kiran Aithal, Sanjita Sasmal, Manoj Pothuganti, Girish Daginakatte, Shekar Chelur, Leena Khare Satyam, Marla Roshaiah, Rangarao Pallepati, Kavitha Nellore, Raghunadh A. Sripathi, Leela P. Narukulla, Suraj Tgore, Susanta Samajdar, Subhendu Mukherjee, Sireesha Nunna
Publikováno v:
Cancer Research. 79:3844-3844
SMARCA2/BRM and SMARCA4/BRG1 are the mutually exclusive DNA-dependent ATPases within the SWI/SNF complexes, which function in mobilizing nucleosomes to regulate transcription, DNA replication and repair, and higher-order chromosome dynamics. SMARCA4
Publikováno v:
Journal of Clinical Oncology. 37:e15655-e15655
e15655 Background: Gallbladder cancer is the most common malignancy of the biliary tract and endemic in Northern India. The prognosis of gallbladder cancer remains dismal despite any treatment because of late presentation and aggressive tumor biology
Autor:
Ashokk Ettam, Leena Khare Satyam, Mohammed A. Shareef, Sireesha Nunna, Sreevalsam Gopinath, Manoj Pothuganti, Murali Ramachandra, Sanjita Sasmal, Susanta Samajdar, Subhendu Mukherjee
Publikováno v:
Cancer Research. 78:LB-258
The SWI/SNF complexes consist of one of two mutually exclusive DNA-dependent ATPases, BRG1/SMARCA4 or BRM/SMARCA2, together with core and accessory subunits that function in mobilizing nucleosomes to regulate transcription, DNA replication and repair
Autor:
Murali Ramachandra, Susanta Samajdar, Ravindra M, Sivapriya Marappan, Subhendu Mukherjee, Bharath E N, Chetan Pandit, Leena Khare Satyam, Girish Daginakatte, Manoj Pothuganti, Amith A, Aravind A B, Sujatha Rajagopalan, Ramulu Poddutoori, Suraj Tgore, Lakshmi Narayana Kaza, Thomas Antony, Charamanna Kb, Sreevalsam Gopinath, Sasirekha Sivakumar, Shekar Chelur
Publikováno v:
Molecular Cancer Therapeutics. 17:B164-B164
Background: Cyclin-dependent kinase 7 (CDK7) is an important constituent of the cellular transcriptional machinery, where it phosphorylates the C-terminal domain (CTD) of RNAP polymerase II (RNAPII). Because many tumor types are critically dependent