Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Leena Karnik"'
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Haploidentical Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide Plus Thiotepa Improves Donor Engraftment in Patients with Sickle Cell Anemia: Results of an International Learning Collaborative
Autor: Kathryn A. Culos, Françoise Bernaudin, Mathieu Kuentz, Josu de la Fuente, Adetola A. Kassim, Michael R. DeBaun, Robert A. Brodsky, Nathalie Dhedin, Gérard Socié, Tatsuki Koyama, Leena Karnik
Publikováno v: Biology of Blood and Marrow Transplantation. 25:1197-1209
Curative therapy for individuals with severe sickle cell disease (SCD) who lack an HLA-identical sibling donor has been frustratingly elusive. In with the goal of improving engraftment while minimizing transplantation-related morbidity, a multi-insti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c70464cd572d3240d6212b98cc87709
https://doi.org/10.1016/j.bbmt.2018.11.027
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5
Complex Clonal Evolution Can Occur Following Transplantation for Transfusion Dependent Thalassaemia in the Context of Mixed Myeloid Chimerism and Reduced Conditioning Regimens
Autor: Leena Karnik, Adam Gassas, Kirstin Lund, Farah O'Boyle, Josu de la Fuente, Shahzya Chaudhury, Toni Petterson
Publikováno v: Blood. 138:2906-2906
Haemopoietic stem cell transplantation (HSCT) is a well-established treatment modality for the cure of transfusion dependent thalassaemia (TDT) and sickle cell disease (SCD). Clonal evolution has recently been identified as a concerning event in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83db712a18daff097a37a7dbb4377064
https://doi.org/10.1182/blood-2021-153519
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8
Non-Myeloablative Bone Marrow Transplant with Post-Transplant Cyclophosphamide Plus Thiotepa Improves Donor Engraftment in Patients with Transfusion Dependent Thalassemia: Results of an International Consortium (VGC2)
Autor: Rabi Hanna, Dilan A Patel, Adetola A. Kassim, Carrie L. Kitko, Leena Karnik, Josu de la Fuente, James A. Connelly
Publikováno v: Biology of Blood and Marrow Transplantation. 26:S221-S222
Background Post-transplant cyclophosphamide (PTCy) enables allogeneic hematopoietic cell transplant (Allo-HCT) across the human leukocyte antigen barrier. Allo-HCT for severe transfusion dependent thalassemia is restricted in its application due to l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::293184f919c73caf3f0d6f8ae4468fa1
https://doi.org/10.1016/j.bbmt.2019.12.540
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10
Early viral reactivation despite excellent immune reconstitution following haploidentical Bone marrow transplant with post-transplant cytoxan for sickle cell disease
Autor: Madan Jagasia, Adetola A. Kassim, Dilan A Patel, Katie S. Gatwood, Nathalie Dhedin, Jim Connelly, Gowri Satyanarayana, Josu de la Fuente, Carrie L. Kitko, Katie Culos, Leena Karnik, Sanjay R. Mohan, Heidi Chen, Brian G. Engelhardt
Publikováno v: Transpl Infect Dis
Background Haploidentical bone marrow transplant (haplo-BMT) offers near universal donor availability as a curative modality for individuals with severe sickle cell disease (SCD). However, the required intense immunodepletion is associated with incre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b7301104ca738105e0c7d0952a6091
https://pubmed.ncbi.nlm.nih.gov/31782875
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