Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leena Harju"'
Autor:
Pirjo Nummela, Erkki Hölttä, Olli Saksela, Margus Lukk, Leena Harju, Susanna Virolainen, Esko Ukkonen, Tiina Jahkola, Johanna Soikkeli, Riku Katainen
Publikováno v:
The Journal of Pathology. 213:180-189
Melanoma is notorious for its high tendency to metastasize and its refractoriness to treatment thereafter. Metastasis is believed to occur mostly through the lymphatic system, and the status of sentinel lymph nodes is currently recognized as the best
Publikováno v:
Journal of Urology. 163:317-322
Purpose: To study short-term events in the mechanism of action of BCG with an emphasis on the interaction between BCG and T24 cell line cells. Materials and Methods: Peripheral blood mononuclear cells (PBMNC) or/and several tumor cell lines were incu
Publikováno v:
Clinical Chemistry. 39:2282-2287
In solid-phase minisequencing, a defined point mutation is detected in microtiter plate-immobilized DNA by a single nucleotide primer extension reaction. We have here developed the method into a colorimetric assay and applied it to the detection of t
Publikováno v:
Genomics. 8:684-692
We describe a new technique by which single base changes in human genes can be conveniently detected. In this method the DNA fragment of interest is first amplified using the polymerase chain reaction with an oligonucleotide primer biotinylated at it
Autor:
Irmeli Lautenschlager, Pasi Jänne, Marjut Ranki, Valeria R.X. Soares, Satu Mattinen, Leena Harju, Marja-Leena Laukkanen, Arja Kallio, Annamari Ranki, Ann-Christine Syvänen, Hans Söderlund
Publikováno v:
Molecular and Cellular Probes. 4:223-235
We have devised a sensitive and convenient hybridization technique by combining the polymerase chain reaction (PCR) with affinity-based hybrid collection. In this method 5'-biotinylated primers are used to introduce biotin residues into the DNA fragm
Autor:
Carl G. Gahmberg, Panu E. Kovanen, Tuomo Timonen, Carmela Kantor, Kimmo Virtaneva, Leena Harju
Publikováno v:
FEBS Letters. (2-3):233-237
The expression and partial purification of recombinant 12 kDa B cell growth factor are reported. The polypeptide was derived from the genomic sequence of the gene (BCGF 1) which is here shown to be a single copy gene that localizes to human chromosom