Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leena Derwish"'
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160529 (2016)
Oncogenic activation of Ras/MEK downregulates the expression of interferon regulatory factor 1 (IRF1), which is a prerequisite for oncolytic viruses to replicate in cancer cells [1]. Moreover, restoration of IRF1 expression is essential to induce apo
Externí odkaz:
https://doaj.org/article/512da92d514a442c92212f1bb5313e90
Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway
Autor:
Karen M. Mearow, Kensuke Hirasawa, Justin J. King, Mani Larijani, Theerawat Pongnopparat, Jayoti Som, Maria Licursi, Leena Derwish, Vipin Shankar Chelakkot, Suzette G Rutihinda, Ema Yoshioka, Ann M. Dorward
Publikováno v:
Theranostics
Protoporphyrin IX (PpIX) is an endogenous fluorescent molecule that selectively accumulates in cancer cells treated with the heme precursor 5-aminolevulinic acid (5-ALA). This cancer-specific accumulation of PpIX is used to distinguish tumor from nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470b288c66f1bda08d66813a8852af98
https://doi.org/10.7150/thno.22641
https://doi.org/10.7150/thno.22641
Autor:
Maria Licursi, Kensuke Hirasawa, Yumiko Komatsu, Leena Derwish, Seyd Razavi, Nader F. AbuSara
Publikováno v:
Cancer letters. 357(2)
Interferon regulatory factor (IRF1) is a potent antiviral, antitumor and immune regulatory protein. Recently, we found that activated Ras/MEK inhibits antiviral response by downregulating IRF1 expression and renders cancer cells susceptible to oncoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b93fb03ea555967bf41616d0b66988
https://pubmed.ncbi.nlm.nih.gov/25497010
https://pubmed.ncbi.nlm.nih.gov/25497010
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160529 (2016)
PLoS ONE
PLoS ONE
Oncogenic activation of Ras/MEK downregulates the expression of interferon regulatory factor 1 (IRF1), which is a prerequisite for oncolytic viruses to replicate in cancer cells [1]. Moreover, restoration of IRF1 expression is essential to induce apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a82a3cbc0e5ee15bdb8b51b55593d7
https://doi.org/10.1371/journal.pone.0160529
https://doi.org/10.1371/journal.pone.0160529