Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Leena, Valmu"'
Autor:
Lotta Kilpinen, Ulla Impola, Lotta Sankkila, Ilja Ritamo, Maria Aatonen, Sami Kilpinen, Jarno Tuimala, Leena Valmu, Jouko Levijoki, Piet Finckenberg, Pia Siljander, Esko Kankuri, Eero Mervaala, Saara Laitinen
Publikováno v:
Journal of Extracellular Vesicles, Vol 2, Iss 0, Pp 1-15 (2013)
Background: Mesenchymal stromal cells (MSC) are shown to have a great therapeutic potential in many immunological disorders. Currently the therapeutic effect of MSCs is considered to be mediated via paracrine interactions with immune cells. Umbilical
Externí odkaz:
https://doaj.org/article/fded3fd7175844c9823774af85ca0943
Autor:
Leena Valmu, Kyösti Kauppinen, Petri Lehenkari, Ilja Ritamo, Meeri Hilli, Jani Luukkonen, Miho Nakamura, Juha Tuukkanen
Publikováno v:
Histochemistry and Cell Biology
Osteopontin (OPN) is a non-collagenous extracellular sialylated glycoprotein located in bone. It is believed to be one of the key components in osteoclast attachment to bone during resorption. In this study, we characterized OPN and other glycoprotei
Autor:
Carolin A Kolmeder, Mark de Been, Janne Nikkilä, Ilja Ritamo, Jaana Mättö, Leena Valmu, Jarkko Salojärvi, Airi Palva, Anne Salonen, Willem M de Vos
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29913 (2012)
The human intestinal tract is colonized by microbial communities that show a subject-specific composition and a high-level temporal stability in healthy adults. To determine whether this is reflected at the functional level, we compared the faecal me
Externí odkaz:
https://doaj.org/article/65672ddedfe245eb801ac96fde51065e
Autor:
Suvi Ravela, Leena Kylänpää, Hannu Koistinen, Leena Valmu, Jakob Stenman, Outi Itkonen, Mykola Domanskyy, Esa Hämäläinen, Ulf-Håkan Stenman, Outi Lindström
Publikováno v:
Analytical and bioanalytical chemistry. 410(6)
Pancreatic secretory trypsin inhibitor Kazal type 1 (SPINK1) is a 6420 Da peptide produced by the pancreas, but also by several other tissues and many tumors. Some mutations of the SPINK1 gene, like the one causing amino acid change N34S, have been s
Autor:
Muriel Jaquet, Mauro Delorenzi, Leena Valmu, Johanna Liebl, Yan Agalarov, Camilla Norrmén, Tatiana V. Petrova, Olga Samuilova, Hélène Maby-El Hajjami, Seppo Ylä-Herttuala, Nawal Houhou, Naoyuki Miura, Nadine Zangger, Konstantin I. Ivanov
Publikováno v:
Mol Cell Biol
One of the key mechanisms linking cell signaling and control of gene expression is reversible phosphorylation of transcription factors. FOXC2 is a forkhead transcription factor that is mutated in the human vascular disease lymphedema-distichiasis and
Autor:
Ilja Ritamo, Werner Reutter, Saara Laitinen, Leena Valmu, Milla Lampinen, Alison V. Nairn, Jarkko Räbinä, Kelley W. Moremen, Suvi Natunen, Virve Pitkänen, Heli Suila
Publikováno v:
Glycobiology. 23:1004-1012
There is an increasing interest in the modification of cell surface glycosylation to improve the properties of therapeutic cells. For example, glycosylation affects the biodistribution of mesenchymal stromal cells (MSCs). Metabolic glycoengineering i
Autor:
Milla Mikkola, Milla Lampinen, Jari Natunen, Juhani Saarinen, Timo Tuuri, Leena Valmu, Minna Tiittanen, Sanna Toivonen, Timo Otonkoski, Kaisa Tamminen, Tero Satomaa, Jukka Partanen, Kaija Alfthan
Publikováno v:
Stem Cells and Development. 22:707-716
Lectins are carbohydrate-binding proteins, which occur ubiquitously in nature and are abundant in all living organisms from bacteria to mammals. They have several biological functions among which cell adhesion is well known and characterized. Based o
Autor:
Jaana Mättö, Carolin A. Kolmeder, Annika Kotovuori, Leena Valmu, Kaarina Lähteenmäki, Willem M. de Vos, Ilja Ritamo, Pirjo Wacklin
Publikováno v:
MALDI-TOF and Tandem MS for Clinical Microbiology. Wiley
MALDI-TOF and Tandem MS for Clinical Microbiology
MALDI-TOF and Tandem MS for Clinical Microbiology
This chapter reviews the technological development of high-resolution tandem mass spectrometry (MS) and its capability in analysis of complex microbial systems, particularly in the human gastrointestinal (GI) tract, and presents a few relevant exampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f6d26082c49befa28c78d03e413556
https://research.wur.nl/en/publications/tandem-mass-spectrometry-in-resolving-complex-gut-microbiota-func
https://research.wur.nl/en/publications/tandem-mass-spectrometry-in-resolving-complex-gut-microbiota-func
Publikováno v:
Glycoconjugate Journal. 30:159-170
Despite recent technical advances in glycan analysis, the rapidly growing field of glycomics still lacks methods that are high throughput and robust, and yet allow detailed and reliable identification of different glycans. LC-MS-MS(2) methods have a
Autor:
Siri Lehtonen, Raija Sormunen, Hannnu Ville Leskelä, Sami Palomäki, Johanna Nystedt, Saara Laitinen, Ilja Ritamo, Mika Pietilä, Katrina Nordström, Petri Lehenkari, Juha Pesälä, Ari Vepsäläinen, Leena Valmu
Publikováno v:
Stem Cells and Development. 21:575-588
Human mesenchymal stem cells (hMSCs) are an attractive choice for a variety of cellular therapies. hMSCs can be isolated from many different tissues and possess unique mitochondrial properties that can be used to determine their differentiation poten