Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance.

Autor: Ursula Mager, Tatjana Degenhardt, Leena Pulkkinen, Marjukka Kolehmainen, Anna-Maija Tolppanen, Jaana Lindström, Johan G Eriksson, Carsten Carlberg, Jaakko Tuomilehto, Matti Uusitupa, Finnish Diabetes Prevention Study Group

Publikováno v: PLoS ONE, Vol 3, Iss 8, p e2941 (2008)

Ghrelin may influence the development of obesity through its role in the control of energy balance, food intake, and regulation of body weight. The effects of ghrelin are mediated via the growth hormone secretagogue receptor (GHSR).We genotyped 7 sin

Externí odkaz: https://doaj.org/article/4380186c1909408dbe2da12c02e844f8

REDUCTION OF SUBACUTE ENDOTOXEMIA COULD MEDIATE BENEFICIAL EFFECTS OF VACCINIUM MYRTILLUS IN METABOLIC SYNDROME - A PBMC GENE EXPRESSION STUDY

Autor: Pirkka V. Kirjavainen, Leena Pulkkinen, Otto Mykkänen, Michiel E. Adriaens, Riitta Törrönen, Riitta Puupponen-Pimiä, Marjukka Kolehmainen, David E. Laaksonen, Kaisa Poutanen, Hannu Mykkänen

Publikováno v: Mykkänen, O T, Kirjavainen, P V, Pulkkinen, L, Mykkänen, H, Törrönen, R, Kolehmainen, M, Adriaens, M, Laaksonen, D E, Puupponen-Pimiä, R & Poutanen, K 2014, ' Reduction of subacute endotoxemia could mediate beneficial effects of vaccinium myrtillus in metabolic syndrome-A PBMC gene expression study ', Acta Horticulturae, vol. 1017, no. January, pp. 369-380 . https://doi.org/10.17660/ActaHortic.2014.1017.45

Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. Anthocyanins are anti-inflammatory compounds in diet, and the major group of polyphenols found in wild European blueberries, bilberries (Vaccinium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf24364c1788d75ed835f5ff13322747
https://doi.org/10.17660/actahortic.2014.1017.45

Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?

Autor: Marjukka Kolehmanien, Leena Pulkkinen, Ursula Schwab, Matti Uusitupa, Vanessa D. de Mello

Publikováno v: Molecular Nutrition & Food Research. 56:1160-1172

Peripheral blood mononuclear cells (PBMCs) generally refer to monocytes and lymphocytes, representing cells of the innate and adaptive immune systems. PBMCs are a promising target tissue in the field of nutrigenomics because they seem to reflect the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a64d9e95ca514fcb8a152fe26259a8c
https://doi.org/10.1002/mnfr.201100685

Mid‐infrared spectroscopy and multivariate curve resolution for analyzing human adipose tissue triacylglycerols

Autor: Ursula Schwab, Matti Uusitupa, Mika Tiainen, Pasi Soininen, Marjukka Kolehmainen, Markku Tammi, Jesper Lundbom, Leena Pulkkinen

Publikováno v: European Journal of Lipid Science and Technology. 112:1308-1314

The aim of this study was to evaluate use of infrared spectroscopy for measuring adipose tissue triacylglycerols (TAGs) with analysis by multivariate curve resolution (MCR). The mid-infrared spectrum was measured with an attenuated total reflection a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6edcacfaffb97d024d3d94b10a60dabc
https://doi.org/10.1002/ejlt.201000330

Tenomodulin gene and obesity-related phenotypes

Autor: Anna-Maija Tolppanen, Leena Pulkkinen, Matti Uusitupa, Marjukka Kolehmainen

Publikováno v: Annals of Medicine. 42:265-275

Different cells of adipose tissue secrete compounds which regulate various biological processes. Changes in body weight, body composition, and amount of fat mass can alter the secretory profile and function of adipose tissue. Comparison of adipose ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a552781397ca86a60a6b2b7a055eef
https://doi.org/10.3109/07853891003801123