Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Leen Vandermosten"'
Autor:
Emilie Pollenus, Hendrik Possemiers, Sofie Knoops, Fran Prenen, Leen Vandermosten, Thao-Thy Pham, Laura Buysrogge, Patrick Matthys, Philippe E. Van den Steen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In both humans and mice, natural killer (NK) cells are important lymphocytes of the innate immune system. They are often considered pro-inflammatory effector cells but may also have a regulatory or pro-resolving function by switching their cytokine p
Externí odkaz:
https://doaj.org/article/e049f955ab3c410e856f45bff4f60acc
Autor:
Emilie Pollenus, Fran Prenen, Hendrik Possemiers, Sofie Knoops, Tania Mitera, Jochen Lamote, Amber De Visscher, Leen Vandermosten, Thao-Thy Pham, Patrick Matthys, Philippe E. Van den Steen
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Conventional natural killer (cNK) cells play an important role in the innate immune response by directly killing infected and malignant cells and by producing pro- and anti-inflammatory cytokines. Studies on their role in malaria
Externí odkaz:
https://doaj.org/article/73893ddf27254417bf00664835051b95
Autor:
Emilie Pollenus, Hendrik Possemiers, Sofie Knoops, Fran Prenen, Leen Vandermosten, Chloë Thienpont, Saeed Abdurahiman, Sofie Demeyer, Jan Cools, Gianluca Matteoli, Jeroen A J Vanoirbeek, Greetje Vande Velde, Philippe E Van den Steen
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011929 (2024)
Plasmodium parasites cause malaria, a global health disease that is responsible for more than 200 million clinical cases and 600 000 deaths each year. Most deaths are caused by various complications, including malaria-associated acute respiratory dis
Externí odkaz:
https://doaj.org/article/e58f5cf4cbf44278908ea85b13b37555
Autor:
Leen Vandermosten, Fran Prenen, Balotin Fogang, Pauline Dagneau de Richecour, Sofie Knoops, Christiane Josiane Donkeu, Cathy Doric Piemba Nguefack, Jean-Voisin Taguebue, Paul Koki Ndombo, Bart Ghesquière, Lawrence Ayong, Philippe E. Van den Steen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMalaria remains a widespread health problem with a huge burden. Severe or complicated malaria is highly lethal and encompasses a variety of pathological processes, including immune activation, inflammation, and dysmetabolism. Previously,
Externí odkaz:
https://doaj.org/article/a8b38e743c8f4dd19f5890e93d371e3c
Autor:
Emilie Pollenus, Thao-Thy Pham, Leen Vandermosten, Queeny Robalo, Hendrik Possemiers, Sofie Knoops, Ghislain Opdenakker, Philippe E. Van den Steen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/9e8f05a97a714ddc8017ea849cd4f0a5
Autor:
Hendrik Possemiers, Thao-Thy Pham, Marion Coens, Emilie Pollenus, Sofie Knoops, Sam Noppen, Leen Vandermosten, Sigrid D'haese, Luna Dillemans, Fran Prenen, Dominique Schols, Blandine Franke-Fayard, Philippe E Van den Steen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010114 (2021)
Malaria is a hazardous disease caused by Plasmodium parasites and often results in lethal complications, including malaria-associated acute respiratory distress syndrome (MA-ARDS). Parasite sequestration in the microvasculature is often observed, but
Externí odkaz:
https://doaj.org/article/18476ed9c37141adacf318dc11721d7b
Autor:
Emilie Pollenus, Thao-Thy Pham, Leen Vandermosten, Queeny Robalo, Hendrik Possemiers, Sofie Knoops, Ghislain Opdenakker, Philippe E. Van den Steen
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Malaria complications are often lethal, despite efficient killing of Plasmodium parasites with antimalarial drugs. This indicates the need to study the resolution and healing mechanisms involved in the recovery from these complications. Plasmodium be
Externí odkaz:
https://doaj.org/article/9d65bb7dfae74480b3bf67bdf0fa3ca7
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009122 (2021)
Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate the outcome of malaria. Despite its clear association with mortality in m
Externí odkaz:
https://doaj.org/article/3677a1178d00456d93e15547a39da447
Autor:
Leen Vandermosten, Thao-Thy Pham, Sofie Knoops, Charlotte De Geest, Natacha Lays, Kristof Van der Molen, Christopher J. Kenyon, Manu Verma, Karen E. Chapman, Frans Schuit, Karolien De Bosscher, Ghislain Opdenakker, Philippe E. Van den Steen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Disease tolerance mechanisms counter the negative effects of infection without decreasing the pathogen load. Here, the authors show that in mouse models of malaria, such disease tolerance can be conferred by adrenal hormones, by preventing excessive
Externí odkaz:
https://doaj.org/article/4a46f7525e7d4cd28340e26b10d771de
Autor:
Leen Vandermosten, Thao-Thy Pham, Hendrik Possemiers, Sofie Knoops, Evelien Van Herck, Julie Deckers, Blandine Franke-Fayard, Tracey J. Lamb, Chris J. Janse, Ghislain Opdenakker, Philippe E. Van den Steen
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-17 (2018)
Abstract Background Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a complication of malaria with a lethality rate of up to 80% despite anti-malarial treatment. It is characterized by a vast infiltration of leukocytes, microhaemo
Externí odkaz:
https://doaj.org/article/05db05b46be74fd5ad88e7a866f8f924