Dietary Emulsifiers Alter Composition and Activity of the Human Gut Microbiota in vitro, Irrespective of Chemical or Natural Emulsifier Origin

Autor: Lisa Miclotte, Kim De Paepe, Leen Rymenans, Chris Callewaert, Jeroen Raes, Andreja Rajkovic, John Van Camp, Tom Van de Wiele

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

The use of additives in food products has become an important public health concern. In recent reports, dietary emulsifiers have been shown to affect the gut microbiota, contributing to a pro-inflammatory phenotype and metabolic syndrome. So far, it

Externí odkaz: https://doaj.org/article/da996e47d2ab4f9f921f784aa47d85da

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses

Autor: Nicholas J. Timpson, Sara Vieira-Silva, Marie Joossens, Rodrigo Bacigalupe, Malte C. Rühlemann, Gwen Falony, Kaitlin H Wade, David A. Hughes, Leen Rymenans, Andre Franke, Susan M. Ring, Chloë Verspecht, Liesbet Henckaerts, Jeroen Raes, Jun Wang, Raul Y. Tito

Publikováno v: Hughes, D A, Bacigalupe, R, Wang, J, Rühlemann, M, Tito, R, Falony, G, Joossens, M, Vieira-Silva, S, Henckaerts, L, Rymenans, L, Verspecht, C, Ring, S M, Franke, A, Wade, K H, Timpson, N J & Raes, J 2020, ' Genome-wide associations of human gut microbiome variation and implications for causal inference analyses ', Nature Microbiology, vol. 5, pp. 1079–1087 . https://doi.org/10.1038/s41564-020-0743-8
Nature microbiology

Recent population-based1–4 and clinical studies5 have identified a range of factors associated with human gut microbiome variation. Murine quantitative trait loci6, human twin studies7 and microbiome genome-wide association studies1,3,8–12 have p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59e31ce46a30171ca1cd6a1c1fccc84
https://doi.org/10.1038/s41564-020-0743-8

Successional Stages in Infant Gut Microbiota Maturation

Autor: Chenyan Shi, Ward Deboutte, Leen Rymenans, Kwe Claude Yinda, Mireia Valles-Colomer, Karoline Faust, Vieira Silva S, Papadaki Mi, Van Espen L, Raul Y. Tito, Leen Beller, Jansen D, Jeroen Raes, Gwen Falony, Zeller M, Van Ranst M, Jelle Matthijnssens

Publikováno v: mBio, Vol 12, Iss 6 (2021)
mBio

Disturbances in the primary colonization of the infant gut can result in lifelong consequences and have been associated with a range of host conditions. Although early-life factors have been shown to affect infant gut microbiota development, our curr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2dbd479186489e6da806e6a024025b
https://lirias.kuleuven.be/handle/20.500.12942/687734

Long-term life history predicts current elderly gut microbiome

Autor: Christoph Leitner, Raimund Pechlaner, Peter Santer, Felix Grabherr, Sebastian Proost, Jorge F. Vázquez-Castellanos, Marlene Notdurfter, Martin Weger, Jiyeon Si, Ann C. Gregory, Leen Rymenans, Herbert Tilg, Stefan Kiechl, Johann Willeit, Peter Willeit, Jeroen Raes, Lindsey Decommer, Gregorio Rungger

Extensive scientific and clinical microbiome studies have explored contemporary variation and dynamics of the gut microbiome in human health and disease1–4, yet the role of long-term life-history effects is underinvestigated. Here, we analyzed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc1e0cd5644dde363ebaa408a72173d9
https://doi.org/10.21203/rs.3.rs-130812/v1

Metformin induces weight loss associated with gut microbiota alteration in non-diabetic obese women: a randomized double-blind clinical trial

Autor: Bagher Larijani, Leen Rymenans, Seyed Davar Siadat, Kristin Verbeke, Zahra Hoseini-Tavassol, Ahmadreza Soroush, Hanieh-Sadat Ejtahed, Jeroen Raes, Raul Y. Tito, Shirin Hasani-Ranjbar

Objective The increasing prevalence of obesity over the past few decades constitutes a global health challenge. Pharmacological therapy is recommended to accompany life-style modification for obesity management. Here, we perform a clinical trial to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a21627aafdf9ac319fef4a581b7ff00
https://lirias.kuleuven.be/handle/123456789/630903