A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation.

Autor: Leen, Eoin N.¹ eoin.leen07@imperial.ac.uk, Sorgeloos, Frédéric², Correia, Samantha¹, Chaudhry, Yasmin², Cannac, Fabien¹, Pastore, Chiara¹, Xu, Yingqi¹, Graham, Stephen C.², Matthews, Stephen J.¹, Goodfellow, Ian G.², Curry, Stephen¹ s.curry@imperial.ac.uk

Publikováno v: PLoS Pathogens. 1/6/2016, Vol. 12 Issue 1, p1-34. 34p.

Norovirus Translation Requires an Interaction between the C Terminus of the Genome-linked Viral Protein VPg and Eukaryotic Translation Initiation Factor 4G

Autor: Chung, Liliane, Bailey, Dalan, Leen, Eoin N, Emmott, Edward P, Chaudhry, Yasmin, Roberts, Lisa O, Curry, Stephen, Locker, Nicolas, Goodfellow, Ian G

Viruses have evolved a variety of mechanisms to usurp the host cell translation machinery to enable translation of the viral genome in the presence of high levels of cellular mRNAs. Noroviruses, a major cause of gastroenteritis in man, have evolved a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d85134b2bfd8a9c684d1ebd799df1bde
http://hdl.handle.net/10044/1/17886

Correction: Structure of a Murine Norovirus NS6 Protease-Product Complex Revealed by Adventitious Crystallisation

Autor: Leen, Eoin N., Baeza, Gabriela, Curry, Stephen

Publikováno v: PLoS ONE, Vol 7, Iss 9 (2012)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f43d4e79b173f761cfcd0006265ecc2
http://europepmc.org/articles/PMC3462170

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Norovirus translation requires an interaction between the C Terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G.

Autor: Chung L; From the Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom., Bailey D; From the Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Leen EN; Department of Life Sciences, Imperial College London, South Kensington, London SW7 2AZ, United Kingdom., Emmott EP; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, United Kingdom, and., Chaudhry Y; From the Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom, Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, United Kingdom, and., Roberts LO; University of Surrey, Faculty of Health and Medical Sciences, School of Biosciences and Medicine, Guildford GU2 7HX, United Kingdom., Curry S; Department of Life Sciences, Imperial College London, South Kensington, London SW7 2AZ, United Kingdom., Locker N; University of Surrey, Faculty of Health and Medical Sciences, School of Biosciences and Medicine, Guildford GU2 7HX, United Kingdom., Goodfellow IG; From the Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom, Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, United Kingdom, and ig299@cam.ac.uk.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2014 Aug 01; Vol. 289 (31), pp. 21738-50. Date of Electronic Publication: 2014 Jun 13.