MOTS-c modulates skeletal muscle function by directly binding and activating CK2.

Autor: Kumagai H; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Kim SJ; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Miller B; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Zempo H; Department of Administrative Nutrition, Faculty of Health and Nutrition, Tokyo Seiei College, Tokyo, Japan., Tanisawa K; Faculty of Sport Sciences, Waseda University, Saitama, Japan., Natsume T; Faculty of Medicine, Tokai University, Kanagawa, Japan., Lee SH; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Wan J; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Leelaprachakul N; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Kumagai ME; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Ramirez R 2nd; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Mehta HH; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Cao K; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Oh TJ; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seongnam, South Korea., Wohlschlegel JA; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Sha J; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Nishida Y; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan., Fuku N; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan., Dobashi S; Institute of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan., Miyamoto-Mikami E; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan., Takaragawa M; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan., Fuku M; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan.; Tsudanuma Central General Hospital, Chiba, Japan., Yoshihara T; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan., Naito H; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan., Kawakami R; Physical Fitness Research Institute, Meiji Yasuda Life Foundation of Health and Welfare, Tokyo, Japan., Torii S; Faculty of Sport Sciences, Waseda University, Saitama, Japan., Midorikawa T; College of Health and Welfare, J.F. Oberlin University, Tokyo, Japan., Oka K; Faculty of Sport Sciences, Waseda University, Saitama, Japan., Hara M; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan., Iwasaka C; Department of Physical Activity Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Yamada Y; Sports and Health Sciences, Graduate School of Biomedical Engineering, Tohoku University, Miyagi, Japan.; Medicine and Science in Sports and Exercise, Graduate School of Medicine, Tohoku University, Miyagi, Japan., Higaki Y; Laboratory of Exercise Physiology, Faculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan., Tanaka K; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan., Yen K; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Cohen P; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.

Publikováno v: IScience [iScience] 2024 Oct 19; Vol. 27 (11), pp. 111212. Date of Electronic Publication: 2024 Oct 19 (Print Publication: 2024).

A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease.

Autor: Kim SJ; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Miller B; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Hartel NG; Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA, USA., Ramirez R 2nd; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Braniff RG; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Leelaprachakul N; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Environmental Toxicology Program, Chulabhorn Graduate Institute, Bangkok, 10210, Thailand., Huang A; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Wang Y; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Arpawong TE; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Crimmins EM; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Wang P; The Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Sun X; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu C; The Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Levy D; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Yen K; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Petzinger GM; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Graham NA; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA, USA.; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA., Jakowec MW; Department of Neurology, University of Southern California, Los Angeles, CA, USA.; Department of Biokinesiology and Physical Therapy, The George and MaryLou Boone Center for Parkinson's Disease Research, University of Southern California, Los Angeles, CA, USA., Cohen P; The Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. hassy@usc.edu.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2024 Feb; Vol. 29 (2), pp. 505-517. Date of Electronic Publication: 2024 Jan 03.

Correction: Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE.

Autor: Miller B; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Neuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA., Kim SJ; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Mehta HH; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Cao K; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Kumagai H; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Thumaty N; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Leelaprachakul N; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Braniff RG; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Jiao H; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Vaughan J; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Diedrich J; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Saghatelian A; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Arpawong TE; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Crimmins EM; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Ertekin-Taner N; Mayo Clinic, Department of Neuroscience, Jacksonville, FL, USA., Tubi MA; Imaging Genetics Center, Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Hare ET; Imaging Genetics Center, Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Braskie MN; Imaging Genetics Center, Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Décarie-Spain L; Human and Evolutionary Biology Section, Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA., Kanoski SE; Neuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA.; Human and Evolutionary Biology Section, Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA., Grodstein F; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Zhao L; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Toga AW; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Wan J; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Yen K; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Cohen P; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. hassy@usc.edu.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Apr; Vol. 28 (4), pp. 1827.

Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4‐induced brain pathology.

Autor: Miller, Brendan¹ (AUTHOR), Kim, Su‐Jeong¹ (AUTHOR), Cao, Kevin¹ (AUTHOR), Mehta, Hemal H.¹ (AUTHOR), Thumaty, Neehar¹ (AUTHOR), Kumagai, Hiroshi¹ (AUTHOR), Iida, Tomomitsu¹ (AUTHOR), McGill, Cassandra¹ (AUTHOR), Pike, Christian J.¹ (AUTHOR), Nurmakova, Kamila² (AUTHOR), Levine, Zachary A.^2,3 (AUTHOR), Sullivan, Patrick M.⁴ (AUTHOR), Yen, Kelvin¹ (AUTHOR), Ertekin‐Taner, Nilüfer⁵ (AUTHOR), Atzmon, Gil^6,7 (AUTHOR), Barzilai, Nir⁶ (AUTHOR), Cohen, Pinchas¹ (AUTHOR) hassy@usc.edu

Publikováno v: Aging Cell. Jul2024, Vol. 23 Issue 7, p1-13. 13p.

Genetic Variations in Susceptibility to Traumatic Muscle Injuries and Muscle Pain among Brazilian High-Performance Athletes.

Autor: Marques, Inês Soares^1,2 (AUTHOR) inesmarques1405@gmail.com, Tavares, Valéria^1,3,4 (AUTHOR) valeria.tavares@ipoporto.min-saude.pt, Vieira Neto, Beatriz^1,5 (AUTHOR) beapedro7@hotmail.com, Lopes, Lucas Rafael^6,7 (AUTHOR) lopes.rlucas02@gmail.com, Goes, Rodrigo Araújo^8,9 (AUTHOR) rodrigogoes4@yahoo.com.br, Guimarães, João António Matheus⁸ (AUTHOR) jmatheusguimaraes@gmail.com, Perini, Jamila Alessandra⁶ (AUTHOR) jamilaperini@yahoo.com.br, Medeiros, Rui^1,3,4,5,10 (AUTHOR) ruimedei@ipoporto.min-saude.pt

Publikováno v: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 6, p3300. 12p.