Partial Product Aware Machine Learning on DNA-Encoded Libraries

Autor: Binder, Polina, Lawler, Meghan, Grady, LaShadric, Carlson, Neil, Leelananda, Sumudu, Belyanskaya, Svetlana, Franklin, Joe, Tilmans, Nicolas, Palacci, Henri

DNA encoded libraries (DELs) are used for rapid large-scale screening of small molecules against a protein target. These combinatorial libraries are built through several cycles of chemistry and DNA ligation, producing large sets of DNA-tagged molecu

Externí odkaz: http://arxiv.org/abs/2205.08020

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Autor: Leelananda, Sumudu P., Jernigan, Robert L., Kloczkowski, Andrzej

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