Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Leela Davies"'
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/01712ffb53764dccb83c5798019f95b2
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) is among the leading causes of death worldwide from a single infectious agent, second only to COVID-19 in 2020. TB is caused by infection with Mycobacterium tuberculosis (Mtb), that results either in a latent or active form of disea
Externí odkaz:
https://doaj.org/article/c05fb02d0ae946bc9944946fb009224b
Autor:
Stephanie Fischinger, Deniz Cizmeci, Sally Shin, Leela Davies, Patricia S. Grace, Aida Sivro, Nonhlanhla Yende-Zuma, Hendrik Streeck, Sarah M. Fortune, Douglas A. Lauffenburger, Kogieleum Naidoo, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
South Africa has the highest prevalence of HIV and tuberculosis (TB) co-infection globally. Recurrent TB, caused by relapse or reinfection, makes up the majority of TB cases in South Africa, and HIV infected individuals have a greater likelihood of d
Externí odkaz:
https://doaj.org/article/8606591427d449929f59cab8b65734f8
Autor:
Esther van Woudenbergh, Edward B. Irvine, Leela Davies, Marwou de Kock, Willem A. Hanekom, Cheryl L. Day, Sarah Fortune, Galit Alter
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Tuberculosis (TB) represents the largest cause of death in human immunodeficiency virus (HIV)-infected individuals in part due to HIV-related CD4+ T cell loss, rendering patients immunocompromised and susceptible to a loss of Mycobacterium t
Externí odkaz:
https://doaj.org/article/6dd70743b50f4efbacbe65ac9b0888a3
Autor:
Galit Alter, Leela Davies, Marwou de Kock, Esther van Woudenbergh, Sarah M. Fortune, Willem A. Hanekom, Cheryl L. Day, Edward B. Irvine
Publikováno v:
mSphere, Vol 5, Iss 3, p e00104-20 (2020)
mSphere, Vol 5, Iss 3 (2020)
mSphere
mSphere, Vol 5, Iss 3 (2020)
mSphere
TB is the leading cause of death from a single infectious agent globally, followed by HIV. Furthermore, TB represents the leading cause of death among people with HIV. HIV is known to cause severe defects in T cell immunity, rendering HIV/TB-coinfect
Autor:
Paula M Peçanha-Pietrobom, Amir M. Mohareb, Jeffrey P. Guenette, David Meredith, Rifat Rahman, Gustavo E. Velásquez, Harrison Tsai, Shamik Bhattacharyya, Leela Davies, Sebastian Urday, Nirav J. Patel, Isaac H. Solomon
Publikováno v:
Open Forum Infectious Diseases
Paracoccidioidomycosis is a dimorphic fungal infection endemic in Latin America. We report a patient with a history of pulmonary paracoccidioidomycosis who presented with relapsed disease in the central nervous system 4 years after initial treatment.
Autor:
Noël P. Burtt, Timothy W. Behrens, Patrick M. Gaffney, Rachel Hackett, Leela Davies, David Altshuler, Melissa Parkin, Deborah S. Cunninghame Graham, Andrew Wong, Robert M. Plenge, Chris Cotsapas, Joan E. Wither, Paul R. Fortin, Casey Gates, Timothy J. Vyse, Candace Guiducci, Mark J. Daly, John D. Rioux, Kathy L. Moser, Robert R. Graham, Christopher J. Lessard, Joanlise M. Leon
Publikováno v:
Nature genetics. 40(9)
Systemic lupus erythematosus (SLE) is an autoimmune disease influenced by genetic and environmental factors. We carried out a genome-wide association scan and replication study and found an association between SLE and a variant in TNFAIP3 (rs5029939,
Autor:
Michael F. Seldin, Noël P. Burtt, Alex Parker, David Altshuler, Melissa Parkin, Robert R. Graham, Elena S. Izmailova, Robert M. Plenge, Stacey Gabriel, Jonathan S. Coblyn, Annette Lee, Julian Maller, Lars Alfredsson, Rachel Barry, Nancy E. Maher, David M. Lee, Shaun Purcell, Itsik Pe'er, David A. Hafler, Elizabeth W. Karlson, Leonid Padyukov, Brendan Blumenstiel, Peter K. Gregersen, Claire Healy, Chris Cotsapas, Michael E. Weinblatt, Nancy A. Shadick, Paul I.W. de Bakker, Ronenn Roubenoff, Benjamin M. Neale, Leela Davies, Mark J. Daly, Elaine F. Remmers, Wendy Winslow, Alkes L. Price, Lars Klareskog, Roberta Glass, Matt DeFelice
To identify susceptibility alleles associated with rheumatoid arthritis, we genotyped 397 individuals with rheumatoid arthritis for 116,204 SNPs and carried out an association analysis in comparison to publicly available genotype data for 1,211 relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83891e5e5a77d21f6c010f8d589dc58b
https://europepmc.org/articles/PMC2652744/
https://europepmc.org/articles/PMC2652744/
Autor:
Wei V. Chen, Leela Davies, John P. Carulli, Mark Seielstad, Lars Klareskog, Michael F. Seldin, Evan Beckman, Lindsey A. Criswell, Annette Lee, Anthony Liew, Adrian Tan, David Altshuler, Houman Khalili, Alamelu Chandrasekaran, Wentian Li, Sven Pettersson, Bo Ding, Anbupalam Thalamuthu, Daniel L. Kastner, Chao Tian, Rick Twee-Hee Ong, Peter K. Gregersen, Chunyu Liu, Robert M. Plenge, Lars Alfredsson, Elaine F. Remmers, Carine Bonnard, Christopher I. Amos, Leonid Padyukov
Publikováno v:
The New England journal of medicine. 357(12)
A B S T R AC T Background Rheumatoid arthritis has a complex mode of inheritance. Although HLA-DRB1 and PTPN22 are well-established susceptibility loci, other genes that confer a modest level of risk have been identified recently. We carried out a ge
Autor:
Timothy W. Behrens, Thearith Koeuth, Leela Davies, Jason W. Bauer, Clarence Gillett, Patrick M. Gaffney, Iva Gunnarsson, Deborah S. Cunninghame Graham, Lindsey A. Criswell, Mark J. Daly, Irina A. Vlasova, Geoffrey Hom, David Altshuler, Ann-Christine Syvänen, Robert R. Graham, Peter K. Gregersen, Gunnel Nordmark, Snaevar Sigurdsson, Robert M. Plenge, Noël P. Burtt, Kathy L. Moser, Michelle Petri, Timothy J. Vyse, Ward A. Ortmann, Chieko Kyogoku, Paul R. Bohjanen, Lars Rönnblom, Robert C. Onofrio, Elisabet Svenungsson, Emily C. Baechler
Systematic genome-wide studies to map genomic regions associated with human diseases are becoming more practical. Increasingly, efforts will be focused on the identification of the specific functional variants responsible for the disease. The challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e158805b61d99faa2f350f5d0419d7e
https://europepmc.org/articles/PMC1847749/
https://europepmc.org/articles/PMC1847749/