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pro vyhledávání: '"Leedman, Peter"'
Akademický článek
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Autor:
Woo, Andrew J., Patry, Chelsea-Ann A., Ghamari, Alireza, Pregernig, Gabriela, Yuan, Daniel, Zheng, Kangni, Piers, Taylor, Hibbs, Moira, Li, Ji, Fidalgo, Miguel, Wang, Jenny Y., Lee, Joo-Hyeon, Leedman, Peter J., Wang, Jianlong, Fraenkel, Ernest, Cantor, Alan B.
Publikováno v:
In Blood Advances 27 August 2019 3(16):2499-2511
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 1: Figure S1. Related to Fig. 1. A Scatter plots showing the associations between different integrated-data cluster (iClust) scores of individual tumor samples. Tumor samples with an iClust value specified in the original TCGA manuscr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f32bb1d02c57bd286c14aa0e70873c0
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 7: Figure S6. Related to Fig. 5. Transcriptional reactivation of HHIP gene by novel CRISPRa combinations does not correlate with changes in promoter DNA methylation in transiently transfected Hep3B cells. A Fold change in HHIP mRNA ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95eec4bc16070fd1b4eb56a1ab99d51d
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 8: Figure S7. Related to Fig. 5. Lentiviral transduction of SpdCas9-TET1-CD or SpdCas9-VPR targeting HHIP or MT1M genes in Hep3B cells. A Schematic representation of the “all-in-one” lentiviral vectors, SpdCas9-TET1-CD and SpdCas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e85449e7f2f7764a4122f865837e2b
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 6: Figure S5. Related to Fig. 5. Tiling the promoter of MT1M and TTC36 tumor suppressor genes with a CRISPRa toolbox in Hep3B HCC cells. A-B Fold change in MT1M (A) and TTC36 (B) mRNA expression evaluated by qRT-PCR 72 h after transie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d1576cdf5b55f3cc6cc34c3224549a
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 5: Figure S4 (part 2). Related to Figs. 3–7. CRISPRa is highly specific in hit-and-run and lentiviral approaches in HCC cell lines. A-K The potential off-target genes (MMP11, MOCOS, PIR, SEMA5A, TMEM14C, HRH1, NACC2, NONO, PPA1, RBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5cb887ec9815f69425107a9e68247e
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 4: Figure S4 (part 1). Related to Figs. 3–7. A Off-target analysis of the ten TSGs reactivated in this study, using the most potent gRNAs. The potential off-target genes (MMP11, MOCOS, PIR, SEMA5A, TMEM14C, HRH1, NACC2, NONO, PPA1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07871c897d8b9ebdb621a7f3e697c4eb
Autor:
Sgro, Agustin, Cursons, Joseph, Waryah, Charlene, Woodward, Eleanor A., Foroutan, Momeneh, Lyu, Ruqian, Yeoh, George C. T., Leedman, Peter J., Blancafort, Pilar
Additional file 9: Figure S8. Related to Fig. 7. Phenotypic reprogramming in Hep3B HCC cells lentivirally transduced with SpdCas9-VPR targeting and upregulating MT1M with G1, PZP with G2, TTC36 with G3, or with NO G as control. A-C Cell viability det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23660c6ff603bb32938ec6e932870c07