Zobrazeno 1 - 10 of 789 pro vyhledávání: '"Leedham S"'
1
Akademický článek
Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease.
Autor: Gordon M; BEST unit, University of Central Lancashire, Preston, UK MGordon@uclan.ac.uk., Nigam GB; University of Oxford Translational Gastroenterology Unit, Oxford, UK., Sinopoulou V; University of Central Lancashire, Preston, Lancashire, UK., Al Bakir I; Gastroenterology Department, Chelsea and Westminster Hospital, London, UK., Bateman AC; Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK., Din S; Gastroenterology, NHS Lothian, Edinburgh, UK.; NHS Research Scotland, Clydebank, West Dunbartonshire, UK., Dolwani S; Gastroenterology, Cardiff and Vale NHS Trust, Cardiff, UK., Dhar A; Gastroenterology, County Durham and Darlington NHS Foundation Trust, Darlington, UK.; School of Health and Life Sciences, Teesside University, Middlesbrough, UK., Faiz OD; Department of Surgery and Cancer or Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; St Mark's Hospital and Academic Institute, London, London, UK., Hayee B; King's College Hospital NHS Foundation Trust, London, UK., Healey C; Gastroenterology, Airedale NHS Foundation Trust, Keighley, UK., Lamb CA; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Leedham S; University of Oxford Translational Gastroenterology Unit, Oxford, UK., Kabir M; University College London, London, UK., Iacucci M; University College Cork, Cork, Cork, Ireland.; University of Birmingham, Birmingham, UK., Hart A; St Mark's Hospital, London, UK., Morris AJ; Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK., Novelli M; Department of Histopathology, University College London, London, UK., Raine T; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Rutter M; University Hospital of North Tees, Stockton-on-Tees, UK., Shepherd NA; Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UK., Subramanian V; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Trudgill NJ; Department of Gastroenterology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK., Vance M; St Mark's Hospital and Academic Institute, London, London, UK., Wilson A; St Mark's Hospital and Academic Institute, London, London, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., White L; Nuffield Department of Medicine, University of Oxford Translational Gastroenterology Unit, Oxford, UK., Wakeman R; Crohn's & Colitis UK, Hatfield, Hertfordshire, UK., East JE; Nuffield Department of Medicine, University of Oxford Translational Gastroenterology Unit, Oxford, UK.
Publikováno v: BMJ open gastroenterology [BMJ Open Gastroenterol] 2024 Nov 29; Vol. 11 (1). Date of Electronic Publication: 2024 Nov 29.
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2
Akademický článek
Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors.
Autor: Domingo E; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Rathee S; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Blake A; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Samuel L; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK., Murray G; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK., Sebag-Montefiore D; Leeds Institute of Medical Research, University of Leeds, LS9 7TF, UK., Gollins S; North Wales Cancer Treatment Centre, Besti Cadwaladr University Health Board, Bodelwyddan, Denbighshire, LL18 5UJ, UK., West N; Leeds Institute of Medical Research, University of Leeds, LS9 7TF, UK., Begum R; Cancer Research & University College London Clinica Trial Unit, London, United Kingdom., Richman S; Leeds Institute of Medical Research, University of Leeds, LS9 7TF, UK., Quirke P; Leeds Institute of Medical Research, University of Leeds, LS9 7TF, UK., Redmond K; The Patrick G Johnston Centre for Cancer Research, Queens University Belfast, Belfast, BT7 9AE, UK., Chatzipli A; Wellcome Sanger Institute, Hinxton, Cambridge, CB10 1RQ, UK., Barberis A; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Hassanieh S; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Mahmood U; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Youdell M; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., McDermott U; Wellcome Sanger Institute, Hinxton, Cambridge, CB10 1RQ, UK., Koelzer V; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department of Oncology and Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Leedham S; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, UK., Tomlinson I; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK., Dunne P; The Patrick G Johnston Centre for Cancer Research, Queens University Belfast, Belfast, BT7 9AE, UK., Buffa FM; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK; Department of Computing Sciences, Bocconi University, Bocconi Institute for Data Science and Analytics (BIDSA), Milano, Italy. Electronic address: francesca.buffa@oncology.ox.ac.uk., Maughan TS; Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK. Electronic address: tim.maughan@oncology.ox.ac.uk.
Publikováno v: EBioMedicine [EBioMedicine] 2024 Aug; Vol. 106, pp. 105228. Date of Electronic Publication: 2024 Jul 16.
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4
Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (Nature Communications, (2020), 11, 1, (995), 10.1038/s41467-019-14275-y)
Autor: Serra E. G., Schwerd T., Moutsianas L., Cavounidis A., Fachal L., Pandey S., Kammermeier J., Croft N. M., Posovszky C., Rodrigues A., Russell R. K., Barakat F., Auth M. K. H., Heuschkel R., Zilbauer M., Fyderek K., Braegger C., Travis S. P., Satsangi J., Parkes M., Thapar N., Ferry H., Matte J. C., Gilmour K. C., Wedrychowicz A., Sullivan P., Moore C., Sambrook J., Ouwehand W., Roberts D., Danesh J., Baeumler T. A., Fulga T. A., Carrami E. M., Ahmed A., Wilson R., Barrett J. C., Elkadri A., Griffiths A. M., Zurek M., Strisciuglio C., Elawad M., Lo B., Arancibia-Carcamo C., Bailey A., Barnes E., Bird-Lieberman E. L., Brain O., Braden B., Collier J., East J., Howarth L., Keshav S., Klenerman P., Leedham S., Palmer R., Powrie F., Simmons A., Walker M., Tolkien Z., Kaptoge S., Allen D., Mehenny S., Mant J., Di Angelantonio E., Thompson S. G., Yilmaz B., Juillerat P., Geuking M., Wiest R., Macpherson A. J., Bravo F. D., Brugger L., Carstens O., Bigler U. G., Heimgartner B., Rusticeanu M., Schmid-Uebelhart S., Strebel B., Tatu A., Tutuian R., Oyas O., Ramon C., Stelling J., Franc Y., Fournier N., Pittet V. E. H., Burnand B., Egger M., Golay D., Marot A., Musso L., Rossel J. -B., Seematter V., Sommer J., Vulliamy R., Michetti P., Maillard M. H., Keller C., Nydegger A., Schoepfe A., Archanioti E., Ezri J., Fraga M., Schoepfer A., Muller C., Rogler G., Biedermann L., Blattmann M., Burk S., Dora B., Fried M., Misselwitz B., Mullhaupt B., Obialo N., Pohl D., Raschle N., Scharl M., Vavricka S., Von Kanel R., Zeitz J., Abdelrahman K., Ademi G., Borovicka J., Brand S., Frei R., Haarer J., Knellwolf-Grieger C., Krieger-Grubel C., Kunzler P., Meyenberger C., Meyer P., Rohrich N., Sawatzki M., Schelling M., Semadeni G. -M., Sulz M., Zimmermann D., Aepli P., Criblez D. H., Hess C., Richterich J. -P., Spalinger J., Staudenmann D., Stulz A., Wohrle S., Thomas A., Anderegg C., Kohler H., Kusche R., Antonino A. -T., Arrigoni E., Bengoa J. M., Cunningham S., de Saussure P., Girard L., de Jong D. B., Basturk P., Brunner S., Degen L., Hruz P., Bakker C. K. -D., Niess J., Balsiger B., Haldemann J., Saner G., Seibold F., Bauerfeind P., Becocci A., Belli D., Binek J., Hengstler P., Boehm S., Boldanov T., Buhr P., Koller R., Rueger V., Senning A., Burri E., Buyse S., Cao D. -T., D'Angelo F., Delarive J., Doerig C., Hessler R., Preissler C., Rentsch R., Risti B., Ritz M. A., Steuerwald M., Vogtlin J., Sagmeister M., Sauter B., Schibli S., Sokollik C., Schlauri H., Schnegg J. -F., Seirafi M., Spangenberger H., Stadler P., Staub P., Stenz V., Tempia-Caliera M., Thorens J., Truninger K., Urfer P., Viani F., Vouillamoz D., Zander S., Wyli T., Jostins L., Kennedy N. A., Ahmad T., Lamb C. A., Edwards C., Hart A., Hawkey C., Mansfield J. C., Mowat C., Newman W. G., Tremelling M., Lee J. C., Prescott N. J., Mathew C. G., Lees C. W., McGovern D. P. B., Targan S. R., Botwin G., Mengesha E., Fleshner P., Landers C., Li D., Rioux J. D., Bitton A., Cote-Daigneault J., Daly M. J., Xavier R., Morris K., Boucher G., Cho J. H., Abraham C., Merad M., Sands B., Peter I., Hao K., Itan Y., Duerr R. H., Konnikova L., Schwartz M. B., Proksell S., Johnston E., Miladinova V., Chen W., Brant S. R., Datta L., Silverberg M. S., Schumm L. P., Birch S., Giri M., Gettler K., Sharma Y., Stevens C., Lazarev M., Haritunians T., Snapper S. B., Shah N., Muise A. M., Wilson D. C., Uhlig H. H., Anderson C. A.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::1924a06abd2de0f946b3818ec4ed8678
https://hdl.handle.net/11591/485482
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Association analyses identify 31 new risk loci for colorectal cancer susceptibility
Autor: Law, PJ, Timofeeva, M, Fernandez-Rozadilla, C, Broderick, P, Studd, J, Fernandez-Tajes, J, Farrington, S, Svinti, V, Palles, C, Orlando, G, Sud, A, Holroyd, A, Penegar, S, Theodoratou, E, Vaughan-Shaw, P, Campbell, H, Zgaga, L, Hayward, C, Campbell, A, Harris, S, Deary, IJ, Starr, J, Gatcombe, L, Pinna, M, Briggs, S, Martin, L, Jaeger, E, Sharma-Oates, A, East, J, Leedham, S, Arnold, R, Johnstone, E, Wang, H, Kerr, D, Kerr, R, Maughan, T, Kaplan, R, Al-Tassan, N, Palin, K, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A-P, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, J-P, Buchanan, DD, Win, A-K, Hopper, J, Jenkins, ME, Lindor, NM, Newcomb, PA, Gallinger, S, Duggan, D, Casey, G, Hoffmann, P, Nöthen, MM, Jöckel, K-H, Easton, DF, Pharoah, PDP, Peto, J, Canzian, F, Swerdlow, A, Eeles, RA, Kote-Jarai, Z, Muir, K, Pashayan, N, Consortium, Practical, Harkin, A, Allan, K, McQueen, J, Paul, J, Iveson, T, Saunders, M, Butterbach, K, Chang-Claude, J, Hoffmeister, M, Brenner, H, Kirac, I, Matošević, P, Hofer, P, Brezina, S, Gsur, A, Cheadle, JP, Aaltonen, LA, Tomlinson, I, Houlston, RS, Dunlop, MG
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide, and has a strong heritable basis. We report a genome-wide association analysis of 34,627 CRC cases and 71,379 controls of European ancestry that identifies SNPs at 31 new C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d8ba9cc2950340d7211cfee43bd4c635
https://doaj.org/article/70e8e953edd64bddb89636d55f3bc15c
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6
Akademický článek
Virtual alignment of pathology image series for multi-gigapixel whole slide images.
Autor: Gatenbee CD; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, 336122, USA. Chandler.Gatenbee@moffitt.org., Baker AM; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Prabhakaran S; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, 336122, USA., Swinyard O; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Slebos RJC; Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, CSB 6, Tampa, FL, USA., Mandal G; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, MRC, Tampa, FL, 336122, USA., Mulholland E; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX37BN, UK., Andor N; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, 336122, USA., Marusyk A; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, USA., Leedham S; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX37BN, UK., Conejo-Garcia JR; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, MRC, Tampa, FL, 336122, USA., Chung CH; Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, CSB 6, Tampa, FL, USA., Robertson-Tessi M; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, 336122, USA., Graham TA; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Anderson ARA; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4, Tampa, FL, 336122, USA. Alexander.Anderson@moffitt.org.
Publikováno v: Nature communications [Nat Commun] 2023 Jul 26; Vol. 14 (1), pp. 4502. Date of Electronic Publication: 2023 Jul 26.
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7
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration
Autor: Koppens, MAJ, Davis, H, Valbuena, GN, Mulholland, E, Simmons, A, Nasreddin, N, East, J, Friedrich, M, Antanaviciute, A, Leedham, S
Background and aims: In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signalling. The Bone Morphogenetic Protein (BMP) pathway has a physiological, pro-differentiation role, predominantly inferred through previous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::5eac93256426419c495ce2abfaadd46b
https://ora.ox.ac.uk/objects/uuid:c86699c6-01fb-4ada-b7b7-d89a76caf869
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8
The evolutionary landscape of colorectal tumorigenesis
Autor: Cross, W., Kovac, M., Mustonen, V., Temko, D., Davis, H., Baker, A.-M., Biswas, S., Arnold, R., Chegwidden, L., Gatenbee, C., Anderson, A.R., Koelzer, V.H., Martinez, P., Jiang, X., Domingo, E., Woodcock, D.J., Feng, Y., Kovacova, M., Maughan, T., Adams, R., Bach, S., Beggs, A., Brown, L., Buffa, F., Cazier, J.-B., Blake, A., Wu, C.-H., Chatzpili, E., Richman, S., Dunne, P., Harkin, P., Higgins, G., Hill, J., Holmes, C., Horgan, D., Kaplan, R., Kennedy, R., Lawler, M., Leedham, S., McDermott, U., McKenna, G., Middleton, G., Morton, D., Murray, G., Quirke, P., Salto-Tellez, M., Samuel, L., Schuh, A., Sebag-Montefiore, D., Seymour, M., Sharma, R., Sullivan, R., Tomlinson, I., West, N., Wilson, R., Jansen, M., Rodriguez-Justo, M., Ashraf, S., Guy, R., Cunningham, C., East, J.E., Wedge, D.C., Wang, L.M., Palles, C., Heinimann, K., Sottoriva, A., Graham, T.A., Tomlinson, I.P.M.
Publikováno v: Cross, W, Kovac, M, Mustonen, V, Temko, D, Davis, H, Baker, A-M, Biswas, S, Arnold, R, Chegwidden, L, Gatenbee, C, Anderson, A R, Koelzer, V H, Martinez, P, Jiang, X, Domingo, E, Woodcock, D J, Feng, Y, Kovacova, M, Maughan, T, Adams, R, Bach, S, Beggs, A, Brown, L, Buffa, F, Cazier, J-B, Domingo, E, Blake, A, Wu, C-H, Chatzpili, E, Richman, S, Dunne, P, Harkin, P, Higgins, G, Hill, J, Holmes, C, Horgan, D, Kaplan, R, Kennedy, R, Lawler, M, Leedham, S, Maughan, T, McDermott, U, McKenna, G, Middleton, G, Morton, D, Murray, G, Quirke, P, Salto-Tellez, M, Samuel, L, Schuh, A, Sebag-Montefiore, D, Seymour, M, Sharma, R, Sullivan, R, Tomlinson, I, West, N, Wilson, R, Jansen, M, Rodriguez-Justo, M, Ashraf, S, Guy, R, Cunningham, C, East, J E, Wedge, D C, Wang, L M, Palles, C, Heinimann, K, Sottoriva, A, Leedham, S, Graham, T A & Tomlinson, I P M 2018, ' The evolutionary landscape of colorectal tumorigenesis ', Nature Ecology and Evolution . https://doi.org/10.1038/s41559-018-0642-z
Nature ecology & evolution
The evolutionary events that cause colorectal adenomas (benign) to progress to carcinomas (malignant) remain largely undetermined. Using multi-region genome/exome sequencing of 24 benign and malignant colorectal tumours, we probe the evolutionary fit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ca8e66b8acd7d108cf45e67d5a470d
http://eprints.whiterose.ac.uk/139375/
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9
Akademický článek
Metastatic recurrence in colorectal cancer arises from residual EMP1 + cells.
Autor: Cañellas-Socias A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Cortina C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Hernando-Momblona X; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Palomo-Ponce S; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Mulholland EJ; Gastrointestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, UK., Turon G; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Mateo L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Conti S; Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Roman O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Sevillano M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Slebe F; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Stork D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Caballé-Mestres A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Berenguer-Llergo A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Álvarez-Varela A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Fenderico N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Novellasdemunt L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Jiménez-Gracia L; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Sipka T; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Bardia L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Lorden P; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Colombelli J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Heyn H; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Trepat X; Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Tejpar S; Digestive Oncology, Department of Oncology, Katholieke Universiteit Leuven, Leuven, Belgium., Sancho E; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Tauriello DVF; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Leedham S; Gastrointestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Oxford, UK., Attolini CS; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Batlle E; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. eduard.batlle@irbbarcelona.org.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain. eduard.batlle@irbbarcelona.org.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. eduard.batlle@irbbarcelona.org.
Publikováno v: Nature [Nature] 2022 Nov; Vol. 611 (7936), pp. 603-613. Date of Electronic Publication: 2022 Nov 09.
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10
Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel
Autor: Fernandez-Rozadilla, C, Kartsonaki, C, Woolley, C, McClellan, M, Whittington, D, Horgan, G, Leedham, S, Kriaucionis, S, East, J, Tomlinson, I
Publikováno v: British Journal of Cancer
Fernandez-Rozadilla, C, Kartsonaki, C, Woolley, C, McClellan, M, Whittington, D, Horgan, G, Leedham, S, Kriaucionis, S, East, J & Tomlinson, I 2018, ' Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel ', British Journal of Cancer, vol. 118, no. 5, pp. 727-732 . https://doi.org/10.1038/bjc.2017.486
Background Colorectal cancer (CRC) screening might be improved by using a measure of prior risk to modulate screening intensity or the faecal immunochemical test threshold. Intermediate molecular biomarkers could aid risk prediction by capturing both
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e53e52f8cae8778de4f10429b6c3f68d
http://ora.ox.ac.uk/objects/uuid:
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