Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Lee-Young Chau"'
Autor:
Yaw-Wen Hsu, Fu-Fei Hsu, Ming-Tsai Chiang, Dong-Lin Tsai, Fu-An Li, Takashi Angata, Paul R. Crocker, Lee-Young Chau
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Abstract Background The accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early atherosclerosis. Siglec-E, a mouse orthologue of human Siglec-9, is a sialic acid binding lectin predominantly expres
Externí odkaz:
https://doaj.org/article/2f0f3b273fa448dba3cf937927f8cb07
Autor:
Yi-Tai Chou, Fu-Fei Hsu, Dun-Yao Hu, Ying-Chih Chen, Yuan-Hao Hsu, John T.-A. Hsu, Lee-Young Chau
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-9 (2018)
Abstract Background Heme oxygenase (HO) catalyzes NADPH-dependent degradation of heme to liberate iron, carbon monoxide and biliverdin. The interaction between HO and cytochrome P450 reductase (CPR), an electron donor, is essential for HO activity. H
Externí odkaz:
https://doaj.org/article/b3ef167c7dae48139c933af8558647c3
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 2, Pp 179-187 (2004)
Heme oxygenase-1 (HO-1) is induced in the CNS after hemorrhage, and may have an effect on injury to surrounding tissue. Hemin, the preferred substrate of HO, is a neurotoxin that is present in intracranial hematomas. In a prior study, we observed tha
Externí odkaz:
https://doaj.org/article/e0c0d0834ba446f6aa2c57a08ae2333c
Autor:
Lee-Young Chau1 lyc@ibms.sinica.edu.tw
Publikováno v:
Journal of Biomedical Science. 2015, Vol. 22 Issue 1, p1-7. 7p. 1 Diagram.
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55369 (2013)
Heme oxygenase-1 (HO-1) is a stress-responsive enzyme with potent anti-oxidant and anti-inflammatory activities. Previous studies have shown that systemic induction of HO-1 by chemical inducers reduces adiposity and improves insulin sensitivity. To d
Externí odkaz:
https://doaj.org/article/6d7f59d25fe546cb8ef4e3ff5edc654d
Autor:
Yaw Wen Hsu, Paul R. Crocker, Dong Lin Tsai, Fu An Li, Lee-Young Chau, Ming Tsai Chiang, Takashi Angata, F. F. Hsu
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
BackgroundThe accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early atherosclerosis. Siglec-E, a mouse orthologue of human Siglec-9, is a sialic acid binding lectin predominantly expressed on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce93fd0a61c3435e4e45f999f2359b7f
https://pubmed.ncbi.nlm.nih.gov/33397354
https://pubmed.ncbi.nlm.nih.gov/33397354
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38626 (2012)
Increased adipose tissue macrophages contribute to obesity-induced metabolic syndrome. Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with potent anti-inflammatory and proangiogenic activities in macrophages. However, the role of macrophage HO-
Externí odkaz:
https://doaj.org/article/48eccaa3ecd24700a99e8658c06e87e9
Autor:
Han-Chung Wu, Patrick C.H. Hsieh, Che Ming Jack Hu, Yuan-Chih Chang, Bill Cheng, Lee-Young Chau, Peilin Chen, Kun-Hung Chen, Elsie K. W. Toh
Publikováno v:
Advanced Healthcare Materials. 5:2686-2697
In patients who survive myocardial infarction, many go on to develop congestive heart failure (CHF). Despite ongoing efforts to develop new approaches for postinfarction therapy, there are still no effective therapeutic options available to CHF patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb4f561dbe11c2f747e5ee3260a1228
https://doi.org/10.1002/adhm.201600724
https://doi.org/10.1002/adhm.201600724
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca8b016a5d8000bb20e9935414be70d
https://doi.org/10.1096/fasebj.2020.34.s1.02093
https://doi.org/10.1096/fasebj.2020.34.s1.02093
Autor:
Chiao Po Hsu, Po Chiao Chang, Dong Lin Tsai, Pei-Kuen Wei, Hsien San Hou, Huan Yuan Chen, Lee-Young Chau, Heng Huei Lin, Chih-Wen Yang, Min-Shao Tsai, Kuo-I Lin, Yi Ru Li, Fu-Tong Liu, Ming Tsai Chiang, Ing-Shouh Hwang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Vascular smooth muscle cell (VSMC) migration play a key role in the development of intimal hyperplasia and atherosclerosis. Galectin-1 (Gal-1) is a redox-sensitive β-galactoside-binding lectin expressed in VSMCs with intracellular and extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9639ee0bc35555257f0d7774975c656
https://doi.org/10.1038/s41598-018-29843-3
https://doi.org/10.1038/s41598-018-29843-3