Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lee-Gau Chong P"'
Publikováno v:
Biophysica, Vol 1, Iss 4, Pp 474-486 (2021)
Liposomes have many advantages as therapeutic capsules over free drugs such as small molecule drugs and nucleic acids. Cholesterol is commonly used as a membrane stabilizing agent in liposomal drugs (e.g., mRNA-lipid nanoparticle COVID-19 vaccines).
Externí odkaz:
https://doaj.org/article/8862f35988714d6a99b30a384fca7bd8
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7616 (2022)
Liposomes and planar membranes made of archaea or archaea-like lipids exhibit many unusual physical properties compared to model membranes composed of conventional diester lipids. Here, we review several recent findings in this research area, which i
Externí odkaz:
https://doaj.org/article/d2612fd79d0b4343b10ddbf15f96b7b2
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12941 (2021)
Bipolar tetraether lipids (BTL) have been long thought to play a critical role in allowing thermoacidophiles to thrive under extreme conditions. In the present study, we demonstrated that not all BTLs from the thermoacidophilic archaeon Sulfolobus ac
Externí odkaz:
https://doaj.org/article/068f292bc913495f813b66f2d4f8a627
Autor:
István P. Sugár, Parkson Lee-Gau Chong
Publikováno v:
AIMS Biophysics, Vol 4, Iss 2, Pp 316-336 (2017)
Here, we model a negatively charged lipid vesicle, composed of a mixture of bipolar tetraether and diester (or diether) phospholipid molecules, by a spherical shell that has zero ion permeability. We take into consideration all the charge-charge inte
Externí odkaz:
https://doaj.org/article/53eb034a15a74595857bca50ef8789c8
Autor:
Umme Ayesa, Parkson Lee-Gau Chong
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8388 (2020)
Archaeosomes have drawn increasing attention in recent years as novel nano-carriers for therapeutics. The main obstacle of using archaeosomes for therapeutics delivery has been the lack of an efficient method to trigger the release of entrapped conte
Externí odkaz:
https://doaj.org/article/18c515815d454ae1ac5f1f6c6382dca4
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5308 (2019)
In this study, we used optical spectroscopy to characterize the physical properties of microvesicles released from the thermoacidophilic archaeon Sulfolobus acidocaldarius (Sa-MVs). The most abundant proteins in Sa-MVs are the S-layer proteins, which
Externí odkaz:
https://doaj.org/article/0af11ad50fad4799acdcae2c57ac9c2f
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3690 (2018)
When using small mole fraction increments to study gramicidins in phospholipid membranes, we found that the phasor dots of intrinsic fluorescence of gramicidin D and gramicidin A in dimyristoyl-sn-glycero-3-phosphocholine (DMPC) unilamellar and multi
Externí odkaz:
https://doaj.org/article/104ec7dcfecc40a9942bd30665475c4e
Publikováno v:
Archaea, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/3496c7d98341470c8bc606ebbe421ee8
Publikováno v:
Archaea, Vol 2012 (2012)
This paper reviews the recent findings related to the physical properties of tetraether lipid membranes, with special attention to the effects of the number, position, and configuration of cyclopentane rings on membrane properties. We discuss the fin
Externí odkaz:
https://doaj.org/article/982416a64eec4d84ac470cb6d71b93b3
Autor:
Wurtzel, Jeremy G.T., Gray, Brian D., Pak, Koon Y., Zhao, Xuefei, Ma, Peisong, McKenzie, Steven E., Tanujaya, Michelle, Rizzo, Victor, Del Carpio-Cano, Fabiola, Rao, A. Koneti, Lee-Gau Chong, Parkson, Goldfinger, Lawrence E.
Publikováno v:
Journal of Thrombosis and Haemostasis; 20240101, Issue: Preprints