Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Lee Zhu A"'
Publikováno v:
Journal of Securities Operations & Custody. Spring2024, Vol. 16 Issue 2, p146-154. 9p.
Autor:
Carolin Loos, Margherita Coccia, Arnaud M. Didierlaurent, Ahmed Essaghir, Jonathan K. Fallon, Douglas Lauffenburger, Corinne Luedemann, Ashlin Michell, Robbert van der Most, Alex Lee Zhu, Galit Alter, Wivine Burny
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract The mechanisms by which antibodies confer protection vary across vaccines, ranging from simple neutralization to functions requiring innate immune recruitment via Fc-dependent mechanisms. The role of adjuvants in shaping the maturation of an
Externí odkaz:
https://doaj.org/article/5c9b578e54b84227946ca060096c90b3
Autor:
Yannic C. Bartsch, Stephanie Fischinger, Sameed M. Siddiqui, Zhilin Chen, Jingyou Yu, Makda Gebre, Caroline Atyeo, Matthew J. Gorman, Alex Lee Zhu, Jaewon Kang, John S. Burke, Matthew Slein, Matthew J. Gluck, Samuel Beger, Yiyuan Hu, Justin Rhee, Eric Petersen, Benjamin Mormann, Michael de St Aubin, Mohammad A. Hasdianda, Guruprasad Jambaulikar, Edward W. Boyer, Pardis C. Sabeti, Dan H. Barouch, Boris D. Julg, Elon R. Musk, Anil S. Menon, Douglas A. Lauffenburger, Eric J. Nilles, Galit Alter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The extent of antibody protection against SARS-CoV-2 remains unclear. Here, using a cohort of 120 seroconverted individuals, the authors longitudinally characterize neutralization, Fc-function, and SARS-CoV-2 specific T cell responses, which they sho
Externí odkaz:
https://doaj.org/article/c9653ceb7d9e4c3a8933d1abc7322637
Autor:
Maya Sangesland, Ashraf S. Yousif, Larance Ronsard, Samuel W. Kazer, Alex Lee Zhu, G. James Gatter, Matthew R. Hayward, Ralston M. Barnes, Maricel Quirindongo-Crespo, Daniel Rohrer, Nils Lonberg, Douglas Kwon, Alex K. Shalek, Daniel Lingwood
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108065- (2020)
Summary: B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and adaptive/hypervariable CDR3 loops to engage antigens. It has long been proposed that the former tune for recognition of
Externí odkaz:
https://doaj.org/article/4869d22e49344399b1979bd3c854bad0
Autor:
Eric J. Nilles, Sameed M. Siddiqui, Stephanie Fischinger, Yannic C. Bartsch, Michael de St. Aubin, Guohai Zhou, Matthew J. Gluck, Samuel Berger, Justin Rhee, Eric Petersen, Benjamin Mormann, Michael Loesche, Yiyuan Hu, Zhilin Chen, Jingyou Yu, Makda Gebre, Caroline Atyeo, Matthew J. Gorman, Alex Lee Zhu, John Burke, Matthew Slein, Mohammad A. Hasdianda, Guruprasad Jambaulikar, Edward W. Boyer, Pardis C. Sabeti, Dan H. Barouch, Boris Julg, Adam J. Kucharski, Elon R. Musk, Douglas A. Lauffenburger, Galit Alter, Anil S. Menon
Publikováno v:
Viruses, Vol 13, Iss 11, p 2235 (2021)
Obesity is a key correlate of severe SARS-CoV-2 outcomes while the role of obesity on risk of SARS-CoV-2 infection, symptom phenotype, and immune response remain poorly defined. We examined data from a prospective SARS-CoV-2 cohort study to address t
Externí odkaz:
https://doaj.org/article/8b482925babd4a6182e66dd7d2a77ac0
Autor:
Shankar Subramaniam, David Veesler, Lauren Carter, David Novack, Claire Sydeman, Jane Fontenot, Douglas E. Ferrell, Galit Alter, Robbert van der Most, Robert L. Coffman, Elizabeth Kepl, Mary Jane Navarro, Alexander G. White, Ching-Lin Hsieh, Kenneth S. Plante, Francois Villinger, Katharina Röltgen, Prabhu S. Arunachalam, Alexandra C. Walls, Jason S. McLellan, Lisa Shirreff, Rino Rappuoli, Sally Shin, Venkata Viswanadh Edara, Jessica A. Plante, Brooke Fiala, Stephanie Fischinger, Chunfeng Li, Caroline Atyeo, Matthew J. Gorman, Chad J. Roy, Scott D. Boyd, Bali Pulendran, Kasi E. Russell-Lodrigue, Skye Spencer, Xiaoying Shen, Shakti Gupta, Derek T. O'Hagan, Pyone P. Aye, Meera Trisal, Neil P. King, JoAnne L. Flynn, Nadia A. Golden, Marcos C. Miranda, Michael E. P. Murphy, John C. Kraft, Mehul S. Suthar, Lilin Lai, Jason Dufour, Rudolph Bohm, Deleah Pettie, Lara A. Doyle-Meyers, David C. Montefiori, Christopher Monjure, Kenneth A. Rogers, Samuel Wrenn, Harry Kleanthous, Nicholas J. Maness, Jay Rappaport, Alex Lee Zhu, Natalie Brunette
Publikováno v:
Nature. 594:253-258
The development of a portfolio of COVID-19 vaccines to vaccinate the global population remains an urgent public health imperative1. Here we demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442cf7639520da9f4126cb4a6dcc72fb
https://doi.org/10.1038/s41586-021-03530-2
https://doi.org/10.1038/s41586-021-03530-2
Autor:
Lisa H. Tostanoski, Alex Van Ry, Alex Lee Zhu, Elyse Teow, Abishek Chandrashekar, Shivani A. Patel, Jinyan Liu, Lauren Peter, Anthony L. Cook, Jake Yalley-Ogunro, Galit Alter, Dan H. Barouch, Mark G. Lewis, Carolin Loos, Gabriel Dagotto, Jingyou Yu, Makda S. Gebre, Mehtap Cabus, Felix Nampanya, Zhenfeng Li, Renita Brown, Douglas A. Lauffenburger, Catherine Jacob-Dolan, Esther A. Bondzie, Kelvin Blade, Laurent Pessaint, Noe B. Mercado, Hanne Andersen, Katherine McMahan, Caroline Atyeo
Publikováno v:
Nature
Recent studies have reported the protective efficacy of both natural1 and vaccine-induced2–7 immunity against challenge with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques. However, the importance of humoral and cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcad23fdba6d201a8bbd3e9018a4bd7
http://europepmc.org/articles/PMC7906955
http://europepmc.org/articles/PMC7906955
Autor:
Nita Patel, Carolin Loos, Ann M. Greene, Douglas A. Lauffenburger, Erica Ollmann Saphire, Fatima Amanat, Ricardo Carrion, Alyse D. Portnoff, Sonia Maciejewski, Florian Krammer, Gale Smith, Caroline Atyeo, Krista M. Pullen, Matthew B. Frieman, Yenny Goez-Gazi, Dansu Yuan, Michael J. Massare, Bin Zhou, Matthew J. Gorman, David C. Montefiori, Marisa McGrath, Colin Mann, Kathryn Bowman, Jing-Hui Tian, Galit Alter, Alex Lee Zhu, Gregory M. Glenn, Mimi Guebre-Xabier, Sharon L. Schendel, Larry Ellingsworth, James Logue
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100405-(2021)
Cell Reports Medicine
Cell Reports Medicine
Recently approved vaccines have shown remarkable efficacy in limiting SARS-CoV-2 associated disease. However, with the variety of vaccines, immunization strategies, and waning antibody titers, defining correlates of immunity across a spectrum of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429d1e038227e64be6dd20fc63a08c1a
http://www.sciencedirect.com/science/article/pii/S2666379121002639
http://www.sciencedirect.com/science/article/pii/S2666379121002639
Autor:
Anthony L. Cook, Hanne Leth Andersen, John-Paul Todd, Sophie Ruiz, Katharine Floyd, Tongqing Zhou, Evan Lamb, Shayne F. Andrew, Britta Flach, Sally Shin, Timothy S. Johnston, Catherine C. Berry, Sarah O’Connell, Nancy J. Sullivan, Joseph R. Francica, Stephanie Fischinger, Alida Tylor, Dapeng Li, Kathryn E. Foulds, Daniel C. Douek, Robert A. Seder, Alex Lee Zhu, Ian N. Moore, Rachel L. Davis, Roman Chicz, Mark G. Lewis, Courtney Tucker, Alex Van Ry, Elizabeth McCarthy, Barney S. Graham, Marguerite Koutsoukos, Robbert van der Most, I.-Ting Teng, Amy T. Noe, Cindy Gutzeit, Matthew Gagne, Mitzi M. Donaldson, Alan Dodson, Tong-Ming Fu, Saule T. Nurmukhambetova, Laurent Pessaint, Venkata Viswanadh Edara, Adrian B. McDermott, Renee van de Wetering, Kizzmekia S. Corbett, Peter D. Kwong, Danilo Casimiro, Timothy Tibbitts, Barbara J. Flynn, Seyhan Boyoglu-Barnum, Valerie Lecouturier, Matthew J. Gorman, Anne P. Werner, Dillon R. Flebbe, Mehul S. Suthar, Mario Roederer, Lilin Lai, Caroline Atyeo, Barton F. Haynes, Galit Alter
Publikováno v:
Science Translational Medicine. 13
Adjuvanted soluble protein vaccines have been used extensively in humans for protection against various viral infections based on their robust induction of antibody responses. Here, soluble prefusion-stabilized spike protein trimers (preS dTM) from s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb238a7d65589e55b35bc8d5d0bacb8e
https://doi.org/10.1126/scitranslmed.abi4547
https://doi.org/10.1126/scitranslmed.abi4547
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.