Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lee Willoughby"'
Autor:
Tamara Zoranovic, Jan Manent, Lee Willoughby, Ricardo Matos de Simoes, John E La Marca, Sofya Golenkina, Xia Cuiping, Susanne Gruber, Belinda Angjeli, Elisabeth Eva Kanitz, Shane J F Cronin, G Gregory Neely, Andreas Wernitznig, Patrick O Humbert, Kaylene J Simpson, Constantine S Mitsiades, Helena E Richardson, Josef M Penninger
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007688 (2018)
Oncogenic mutations in the small GTPase Ras contribute to ~30% of human cancers. However, Ras mutations alone are insufficient for tumorigenesis, therefore it is paramount to identify cooperating cancer-relevant signaling pathways. We devised an in v
Externí odkaz:
https://doaj.org/article/398b05ace50540ebbc5d12234222f441
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 661-678 (2013)
SUMMARY The Ras oncogene contributes to ∼30% of human cancers, but alone is not sufficient for tumorigenesis. In a Drosophila screen for oncogenes that cooperate with an activated allele of Ras (RasACT) to promote tissue overgrowth and invasion, we
Externí odkaz:
https://doaj.org/article/96241f11efee4e5d84cb856094fa2a13
Autor:
Lee Willoughby, Phillip J. Daborn, Charles Robin, Philip J. Batterham, Chris Lumb, Henry F.L. Chung
Publikováno v:
Insect Biochemistry and Molecular Biology. 36:934-942
Modifications of metabolic pathways are important in insecticide resistance evolution. Mutations leading to changes in expression levels or substrate specificities of cytochrome P450 (P450), glutathione-S-transferase (GST) and esterase genes have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f58db52f3a5e7fa548f434694c0570
https://doi.org/10.1016/j.ibmb.2006.09.004
https://doi.org/10.1016/j.ibmb.2006.09.004
Autor:
Scott J. Morledge-Hampton, Robert O. Kwon, Thomas Lee Willoughby, Peter W DeBry, Rohit Krishna
Publikováno v:
Canadian Journal of Ophthalmology. 41:722-726
Background: To compare intraocular pressures obtained using a handheld pressure phosphene tonometer (PPT) (Proview, Bausch & Lomb Pharmaceuticals, Inc., Tampa, Fla.) with Goldmann applanation tonometry. Methods: Comparative case series of 30 randomly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ef8764006a45a138d82aa2a1b17c5e
https://doi.org/10.3129/i06-065
https://doi.org/10.3129/i06-065
Publikováno v:
Teaching and Learning in Medicine. 9:192-199
Background: Understanding factors in specialty choice may increase the number of primary care practitioners. Purpose: The purpose of this study was to learn how primary and nonprimary care graduates differed on entry to medical school, during medical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a961b90e1ba9942915cf92bce57d74aa
https://doi.org/10.1080/10401339709539840
https://doi.org/10.1080/10401339709539840
Autor:
Henry F.L. Chung, Lee Willoughby, Phillip J. Daborn, Chris Lumb, Adrian Boey, Philip J. Batterham
Publikováno v:
Insect biochemistry and molecular biology. 41(11)
Organisms induce the expression of detoxification enzymes such as cytochrome P450s to deal with xenobiotics encountered in the environment. Research using cell culture systems has identified some of the cis-regulatory elements (CREs) and transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d884a599ab8eeaf4aeecd1ac11b5554
https://pubmed.ncbi.nlm.nih.gov/21807095
https://pubmed.ncbi.nlm.nih.gov/21807095
Autor:
Alice Rae Bixby, Thomas Lee Willoughby
Publikováno v:
Educational and Psychological Measurement. 51:691-697
The Quarterly Profile Examination (QPE) is produced by a computer-assisted test construction system designed for the longitudinal measurement of the acquisition and retention of knowledge of the medical sciences. QPE scores from two graduating classe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::343e7294521ef2dca3d6c21279cb2d44
https://doi.org/10.1177/0013164491513020
https://doi.org/10.1177/0013164491513020
Publikováno v:
Pest management science. 63(8)
Piperonyl butoxide (PBO) is an insecticide synergist known to inhibit the activity of cytochrome P450 enzymes. PBO is currently used in some insecticide formulations, and has also been suggested as a pretreatment for some pesticide applications. Litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d65928c66c59057364b6b0b04c4ad
https://pubmed.ncbi.nlm.nih.gov/17514638
https://pubmed.ncbi.nlm.nih.gov/17514638
Autor:
Kenneth Gerald, Frederick J. McCoy, David C. Morris, Durl O'neil, Lee Willoughby, Daniel Remmler, Beth Patterson
Publikováno v:
Plastic and reconstructive surgery. 89(5)
A study of cranial vault lengthening using a custom expandable fixation-distraction (craniotatic) appliance was performed in the young-adult rabbit model. Ten 24-week-old rabbits underwent circumferential suturectomy plus expansion (expanded group),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92afdd61e40aa5826eb54c50685bfd0d
https://pubmed.ncbi.nlm.nih.gov/1561249
https://pubmed.ncbi.nlm.nih.gov/1561249
Publikováno v:
Educational & Psychological Measurement; Jul1977, Vol. 37 Issue 2, p445-449, 5p