Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Lee W Goneau"'
Autor:
Christopher Kandel, Jennifer Zheng, Janine McCready, Mihaela Anca Serbanescu, Hilary Racher, Melissa Desaulnier, Jeff E Powis, Kyle Vojdani, Laura Finlay, Elena Sheldrake, Christie Vermeiren, Kevin Katz, Allison McGeer, Robert Kozak, Lee W Goneau
Publikováno v:
Viruses, Vol 12, Iss 11, p 1314 (2020)
Widely available and easily accessible testing for COVID-19 is a cornerstone of pandemic containment strategies. Nasopharyngeal swabs (NPS) are the currently accepted standard for sample collection but are limited by their need for collection devices
Externí odkaz:
https://doaj.org/article/4cd38d396038484ca2f4487a0b35e002
Autor:
Gregory Morgan, Selina Casalino, Sunakshi Chowdhary, Erika Frangione, Chun Yiu Jordan Fung, Simona Haller, Elisa Lapadula, Mackenzie Scott, Dawit Wolday, Juliet Young, Saranya Arnoldo, Navneet Aujla, Erin Bearss, Alexandra Binnie, Yvonne Bombard, Bjug Borgundvaag, Laurent Briollais, Marc Dagher, Luke Devine, Hanna Faghfoury, Steven M. Friedman, Anne-Claude Gingras, Lee W. Goneau, Zeeshan Khan, Tony Mazzulli, Shelley L. McLeod, Romina Nomigolzar, Abdul Noor, Trevor J. Pugh, David Richardson, Harpreet Kaur Satnam Singh, Jared Simpson, Seth Stern, Lisa Strug, Ahmed Taher, Jordan Lerner-Ellis, Jennifer Taher
Publikováno v:
Viruses, Vol 15, Iss 8, p 1764 (2023)
The GENCOV study aims to identify patient factors which affect COVID-19 severity and outcomes. Here, we aimed to evaluate patient characteristics, acute symptoms and their persistence, and associations with hospitalization. Participants were recruite
Externí odkaz:
https://doaj.org/article/1506a59a12fb42399b492e89b9c90212
Autor:
Selina Casalino, Erika Frangione, Monica Chung, Georgia MacDonald, Sunakshi Chowdhary, Chloe Mighton, Hanna Faghfoury, Yvonne Bombard, Lisa Strug, Trevor J. Pugh, Jared Simpson, Saranya Arnoldo, Navneet Aujla, Erin Bearss, Alexandra Binnie, Bjug Borgundvaag, Howard Chertkow, Marc Clausen, Marc Dagher, Luke Devine, David Di Iorio, Steven Marc Friedman, Chun Yiu Jordan Fung, Anne-Claude Gingras, Lee W. Goneau, Deepanjali Kaushik, Zeeshan Khan, Elisa Lapadula, Tiffany Lu, Tony Mazzulli, Allison McGeer, Shelley L. McLeod, Gregory Morgan, David Richardson, Harpreet Singh, Seth Stern, Ahmed Taher, Iris Wong, Natasha Zarei, Elena Greenfeld, Limin Hao, Matthew Lebo, William Lane, Abdul Noor, Jennifer Taher, Jordan Lerner-Ellis
Publikováno v:
Human Genetics. 142:181-192
Rapid advancements of genome sequencing (GS) technologies have enhanced our understanding of the relationship between genes and human disease. To incorporate genomic information into the practice of medicine, new processes for the analysis, reporting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b591cd0ac940bc79a5a07db2ed0cd86a
https://doi.org/10.1007/s00439-022-02480-7
https://doi.org/10.1007/s00439-022-02480-7
Autor:
Mihaela Anca Serbanescu, James Callahan, Hilary Racher, Lee W. Goneau, Christie Vermeiren, Omid Kyle Vojdani, Janine McCready, Allison McGeer, Dorothy Quon, Christopher Kandel, Elena Sheldrake, Kevin Katz, Jeff Powis, Matthew Young, David Bulir
Publikováno v:
Infection Control & Hospital Epidemiology
Infection Control and Hospital Epidemiology
Infection Control and Hospital Epidemiology
Background:Widespread testing for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) is necessary to curb the spread of coronavirus disease 2019 (COVID-19), but testing is undermined when the only option is a nasopharyngeal swab. Self-collecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d851d4d63cc4b97e940d4d42509ef7a
https://doi.org/10.1017/ice.2021.2
https://doi.org/10.1017/ice.2021.2
Autor:
Vithusha Ravirajan, Harry L.A. Janssen, Alex Marchand-Austin, Hemant Shah, Beate Sander, Kirby Cronin, Natasha Nanwa, Lee W. Goneau, Jordan J. Feld, Tony Mazzulli, Mia J. Biondi, Erin Mandel, Camelia Capraru
Publikováno v:
CMAJ : Canadian Medical Association Journal
BACKGROUND: Ontario is 1 of 5 provinces that immunize adolescents for hepatitis B virus (HBV), despite the World Health Organization recommendation for universal birth dose vaccination. One rationale for not vaccinating at birth is that universal pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23a25345bb1b2110457767641c4de99
https://doi.org/10.1503/cmaj.200290
https://doi.org/10.1503/cmaj.200290
Autor:
Lee W. Goneau, Thomas J. Hannan, Roderick A. MacPhee, Drew J. Schwartz, Jean M. Macklaim, Gregory B. Gloor, Hassan Razvi, Gregor Reid, Scott J. Hultgren, Jeremy P. Burton
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT The capacity of subinhibitory levels of antibiotics to modulate bacterial virulence in vitro has recently been brought to light, raising concerns over the appropriateness of low-dose therapies, including antibiotic prophylaxis for recurrent
Externí odkaz:
https://doaj.org/article/71cdc9b505b747b28355f83dc166f593
Autor:
C. Y. Seo, Sarah E. Wilson, Patrick Stapleton, Snehal Patel, S. Bolotin, T. Harris, Shelley L. Deeks, Alireza Eshaghi, Lee W. Goneau, Jonathan B. Gubbay
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
In 2017 Ontario experienced the largest mumps outbreak in the province in 8 years, at a time when multiple outbreaks were occurring across North America. Of 259 reported cases, 143 occurred in Toronto, primarily among young adults. Routine genotyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4494c26272ea86607daba4b02bd7ea
http://link.springer.com/article/10.1038/s41598-019-47740-1
http://link.springer.com/article/10.1038/s41598-019-47740-1
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 94:15-21
The isolation of stool pathogens is difficult due to their fastidious nature and the rapid overgrowth of fecal flora. In this study, we evaluate the preservation and isolation of enteric pathogens from stool using the automated COPAN Walk-Away Specim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7a5d676a679581a73cfadc0b268571
https://doi.org/10.1016/j.diagmicrobio.2018.11.020
https://doi.org/10.1016/j.diagmicrobio.2018.11.020
Autor:
Jonathan B. Gubbay, Lee W. Goneau, Kevin A. Brown, Jessica Hopkins, Samir N. Patel, Sarah A Buchan, Nick Daneman
A novel variant of SARS-CoV-2, B.1.1.7, originally discovered in the United Kingdom (UK), is rapidly overtaking other strains around the globe. In certain assays, absence of detection of the S-gene target, also known as S-gene target failure (SGTF) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9ad8ac91f0f2543eaf96c8cc783f838
https://doi.org/10.1101/2021.02.09.21251225
https://doi.org/10.1101/2021.02.09.21251225
Autor:
Lee W. Goneau, Susan M. Poutanen, Johannes Delport, Gregor Reid, Jeremy P. Burton, Luana Langlois, Hassan Razvi
Publikováno v:
FEMS Microbes. 1
The administration of antibiotics while critical for treatment, can be accompanied by potentially severe complications. These include toxicities associated with the drugs themselves, the selection of resistant organisms and depletion of endogenous ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b717860ee106ce315462888b561994a
https://doi.org/10.1093/femsmc/xtaa004
https://doi.org/10.1093/femsmc/xtaa004