Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lee S. Gottesdiener"'
Autor:
Han A Li, Lee S. Gottesdiener, Graham T Wehmeyer, Justin J Choi, Lars F. Westblade, Kyle Liang, Matthew S. Simon, Marshall J. Glesby
Publikováno v:
Open Forum Infectious Diseases
Background Multiplex polymerase chain reaction (PCR) panels allow for rapid detection or exclusion of pathogens causing meningitis and encephalitis (ME). The clinical impact of rapid multiplex PCR ME panel results on the duration of empiric antibioti
Autor:
Helen Won, David B. Solit, Alexander N. Shoushtari, Klaus J. Busam, David M. Hyman, Lee S. Gottesdiener, Shannon O'Connor
Publikováno v:
Clinical Cancer Research. 24:5815-5819
Purpose: Patients with BRAF V600 wild-type melanoma whose tumors progress on checkpoint inhibition currently have limited therapeutic options, and additional rational treatment targets are needed. ERBB2 alterations may be amenable to targeted inhibit
Autor:
Mercedes Duran, Princesca Dorsaint, Julie-Ann Cavallo, Shin-San Michael Su, Dhruva Biswas, Taha Merghoub, Maria Laura Martin, Sreeram Vallabhaneni, Simon N. Powell, Manuel Salto-Tellez, Jedd D. Wolchok, Neil Vasan, Anusha Kalbasi, Nadeem Riaz, Hannah Y Wen, Samuel F. Bakhoum, Jun Li, Benjamin J DiPardo, Jacqueline James, Charles Swanton, Lee S. Gottesdiener, Olivier Elemento, John Kwon, Benjamin Izar, Alexander N. Shoushtari, Rohan Bareja, Hao Wei Li, Matthew G. Hanna, Johannes C. Melms, Ieva Usaite, Kevin Litchfield, Ninjit Dhanota, Matthew P. Humphries, Eileen Parkes, Travis J Hollmann, Roshan K. Sriram, Chantal Pauli, Sarah E Bettigole, Jorge S. Reis-Filho, Peng Li, Walid K. Chatila
Publikováno v:
Li, J, Duran, M A, Dhanota, N, Chatila, W K, Bettigole, S E, Kwon, J, Sriram, R K, Humphries, M P, Salto-Tellez, M, James, J A, Hanna, M G, Melms, J C, Vallabhaneni, S, Litchfield, K, Usaite, I, Biswas, D, Bareja, R, Li, H W, Martin, M L, Dorsaint, P, Cavallo, J-A, Li, P, Pauli, C, Gottesdiener, L, DiPardo, B J, Hollmann, T J, Merghoub, T, Wen, H Y, Reis-Filho, J S, Riaz, N, Su, S-S M, Kalbasi, A, Vasan, N, Powell, S N, Wolchok, J D, Elemento, O, Swanton, C, Shoushtari, A N, Parkes, E E, Izar, B & Bakhoum, S F 2020, ' Metastasis and immune evasion from extracellular cGAMP hydrolysis ', Cancer discovery, vol. Early Online, pp. xx . https://doi.org/10.1158/2159-8290.CD-20-0387
Cancer Discov
Cancer Discov
Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3a80cefbaee3bdab1ee35690a87c04
https://pure.qub.ac.uk/en/publications/metastasis-and-immune-evasion-from-extracellular-cgamp-hydrolysis(6d7c17ea-11d5-406d-8d68-1f1010b32751).html
https://pure.qub.ac.uk/en/publications/metastasis-and-immune-evasion-from-extracellular-cgamp-hydrolysis(6d7c17ea-11d5-406d-8d68-1f1010b32751).html
Autor:
Alexander N. Shoushtari, Suthee Rapisuwon, Deborah L. Berry, David Goerlitz, Michael B. Atkins, Douglas B. Johnson, Garrett T. Graham, Lee S. Gottesdiener, Daniel Ying Wang
Publikováno v:
Journal of Clinical Oncology. 37:9546-9546
9546 Background: MCM is a rare melanoma subtype (only 1% of melanomas in the US). MCM has a lower tumor mutational burden than cutaneous melanoma (CM). While some patients (pts) with MCM respond to immune checkpoint inhibitor (ICI) therapy, predictiv
Autor:
Parisa Momtaz, Mahmoud Eljalby, Jedd D. Wolchok, Michael Gormally, Alexander N. Shoushtari, Marc Cohen, Mario M. Leitao, Paul B. Chapman, Lee S. Gottesdiener, Michael A. Postow, Margaret K. Callahan, Joshua Armenia, Nikolaus Schultz, Travis Hollman
Publikováno v:
Journal of Clinical Oncology. 36:e21579-e21579
e21579Background: Mucosal melanomas (McM) have lower tumor mutational burden (TMB) and higher fraction of genome with alterations (FGA) than cutaneous melanomas. Sequencing efforts to date suggest ...