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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Human Leukocyte Antigen B (HLA-B) Genotype and Allopurinol Dosing: 2015 Update.

Autor: Saito, Y, Stamp, LK, Caudle, KE, Hershfield, MS, McDonagh, EM, Callaghan, JT, Tassaneeyakul, W, Mushiroda, T, Kamatani, N, Goldspiel, BR, Phillips, EJ, Klein, TE, Lee, MTM

Publikováno v: Clinical Pharmacology & Therapeutics; Jan2016, Vol. 99 Issue 1, p36-37, 2p

A Functional Polymorphism Downstream of Vitamin A Regulator Gene CYP26B1 Is Associated with Hand Osteoarthritis.

Autor: Khosasih V; Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei 115, Taiwan.; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Liu KM; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Huang CM; Division of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital, Taichung 404, Taiwan.; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan., Liou LB; Division of Rheumatology, Allergy and Immunology, New Taipei Municipal Tucheng Hospital, New Taipei City 236, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan., Hsieh MS; Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Department of Orthopedics, Taipei Medical University Hospital, Taipei 110, Taiwan.; Department of Orthopedics, En Chu Kong Hospital, New Taipei 237, Taiwan., Lee CH; Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Department of Orthopedics, Taipei Medical University Hospital, Taipei 110, Taiwan., Tsai CY; School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Division of Allergy, Immunology and Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan., Kuo SY; Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan., Hwa SY; Department of Orthopaedics, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan., Yu CL; Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan., Chang CH; Department of Orthopedics, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei 100, Taiwan.; Department of Orthopedics, National Taiwan University Hospital Jin-Shan Branch, New Taipei City 208, Taiwan., Lin CJ; Department of Orthopedics, China Medical University Hospital, Taichung 404, Taiwan., Hsieh SC; Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan., Cheng CY; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Orthopedic, Chang Gung Memorial Hospital, Linkou, Taoyuan 333, Taiwan., Chen WM; School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Orthopaedics and Traumatology, Taipei Veteran General Hospital, Taipei 112, Taiwan., Chen LK; Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan., Chuang HP; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Chen YT; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Tsai PC; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Lu LS; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., H'ng WS; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan., Zhang Y; Genomic Medicine Institute, Geisinger, Danville, PA 17822, USA., Chen HC; Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan., Chen CH; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.; School of Chinese Medicine, China Medical University, Taichung 404, Taiwan., Lee MTM; Genomic Medicine Institute, Geisinger, Danville, PA 17822, USA.; School of Chinese Medicine, China Medical University, Taichung 404, Taiwan., Wu JY; Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei 115, Taiwan.; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.; School of Chinese Medicine, China Medical University, Taichung 404, Taiwan.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 03; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 03.

Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.

Autor: Zhou W; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kanai M; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan., Wu KH; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Rasheed H; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Division of Medicine and Laboratory Sciences, University of Oslo, Oslo, Norway.; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK., Tsuo K; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hirbo JB; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Wang Y; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bhattacharya A; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Zhao H; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK., Namba S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan., Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Wolford BN; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Lo Faro V; University of Groningen, UMCG, Department of Ophthalmology, Groningen, the Netherlands.; Department of Clinical Genetics, Amsterdam University Medical Center (AMC), Amsterdam, the Netherlands.; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lopera-Maya EA; University of Groningen, UMCG, Department of Genetics, Groningen, the Netherlands., Läll K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Favé MJ; Ontario Institute for Cancer Research, Toronto, ON, Canada., Partanen JJ; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Chapman SB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Karjalainen J; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Kurki M; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Maasha M; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Brumpton BM; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Chavan S; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Chen TT; Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan., Daya M; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Ding Y; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA., Feng YA; Division of Biostatistics, Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Guare LA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gignoux CR; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Hornsby WE; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Ingold N; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia., Ismail SI; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar., Johnson R; Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Laisk T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lv J; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Moreno-Grau S; Galatea Bio, Inc., Hialeah, FL, USA., Nam K; Graduate School of Data Science, Seoul National University, Seoul, South Korea., Palta P; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Pandit A; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Saad C; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar., Setia-Verma S; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., 101 Reykjavik, Iceland., Uzunovic J; Ontario Institute for Cancer Research, Toronto, ON, Canada., Verma A; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA., Zawistowski M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Zhong X; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Afifi N; Qatar Biobank for Medical Research, Qatar Foundation for Education, Science, and Community, Doha, Qatar., Al-Dabhani KM; Qatar Biobank for Medical Research, Qatar Foundation for Education, Science, and Community, Doha, Qatar., Al Thani A; Qatar Biobank for Medical Research, Qatar Foundation for Education, Science, and Community, Doha, Qatar., Bradford Y; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Crooks K; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., de Bock GH; Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands., Damrauer SM; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Douville NJ; Department of Anesthesiology, Michigan Medicine, Ann Arbor, MI, USA.; Institute of Healthcare Policy & Innovation, University of Michigan, Ann Arbor, MI, USA., Finer S; Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Fritsche LG; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Fthenou E; Qatar Biobank for Medical Research, Qatar Foundation for Education, Science, and Community, Doha, Qatar., Gonzalez-Arroyo G; Galatea Bio, Inc., Hialeah, FL, USA.; Amphora Health, Morelia, Michoacan, Mexico., Griffiths CJ; Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Guo Y; Chinese Academy of Medical Sciences, Beijing, China., Hunt KA; Blizard Institute, Queen Mary University of London, London, UK., Ioannidis A; Galatea Bio, Inc., Hialeah, FL, USA.; Stanford University School of Medicine, Stanford, CA, USA., Jansonius NM; University of Groningen, UMCG, Department of Ophthalmology, Groningen, the Netherlands., Konuma T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.; Central Pharmaceutical Research Institute, Japan Tobacco, Inc., Takatsuki 569-1125, Japan., Lee MTM; Galatea Bio, Inc., Hialeah, FL, USA., Lopez-Pineda A; Galatea Bio, Inc., Hialeah, FL, USA.; Amphora Health, Morelia, Michoacan, Mexico., Matsuda Y; Genomelink, Inc., Berkeley, CA, USA., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Moatamed B; Galatea Bio, Inc., Hialeah, FL, USA., Nava-Aguilar MA; Galatea Bio, Inc., Hialeah, FL, USA.; Amphora Health, Morelia, Michoacan, Mexico., Numakura K; Genomelink, Inc., Berkeley, CA, USA., Patil S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Rafaels N; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Richmond A; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Rojas-Muñoz A; Galatea Bio, Inc., Hialeah, FL, USA., Shortt JA; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Straub P; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Tao R; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Vanderwerff B; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Vernekar M; Genomelink, Inc., Berkeley, CA, USA., Veturi Y; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Barnes KC; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Boezen M; Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Chen CY; Biogen, Cambridge, MA, USA., Cho J; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Smith GD; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; NIHR Bristol Biomedical Research Centre, Bristol, UK., Finucane HK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Franke L; University of Groningen, UMCG, Department of Genetics, Groningen, the Netherlands., Gamazon ER; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Ganna A; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; NIHR Bristol Biomedical Research Centre, Bristol, UK., Ge T; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Precision Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Huang H; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Huffman J; Centre for Population Genomics, VA Boston Healthcare System, Boston, MA, USA., Katsanis N; Galatea Bio, Inc., Hialeah, FL, USA., Koskela JT; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Lajonchere C; Institute of Precision Health, University of California, Los Angeles, Los Angeles, CA, USA.; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Law MH; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Lindgren CM; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Medicine and Health Sciences, University of Copenhagen, Copenhagen, Denmark., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Matsuda K; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Olsen CM; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Shavit JA; University of Michigan, Department of Pediatrics, Ann Arbor, MI 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Snieder H; Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands., Takano T; Genomelink, Inc., Berkeley, CA, USA., Trembath RC; School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Vonk JM; Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands., Whiteman DC; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Wicks SJ; University of Colorado - Anschutz Medical Campus, Aurora, CO, USA., Wijmenga C; University of Groningen, UMCG, Department of Genetics, Groningen, the Netherlands., Wright J; Bradford Institute for Health Research, Bradford Teaching Hospitals National Health Service (NHS) Foundation Trust, Bradford, UK., Zheng J; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK., Zhou X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Awadalla P; Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bustamante CD; Galatea Bio, Inc., Hialeah, FL, USA.; Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Cox NJ; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Fatumo S; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda.; London School of Hygiene & Tropical Medicine, London, UK.; Medical Research Council/Uganda Virus Research Institute/London School of Hygiene and Tropical Medicine (MRC/UVRI/LSHTM) Uganda Research Unit, Entebbe, Uganda., Geschwind DH; Institute of Precision Health, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway., Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lee S; Graduate School of Data Science, Seoul National University, Seoul, South Korea., Lin YF; Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan.; Department of Public Health & Medical Humanities, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Mbarek H; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Martin HC; Human Genetics Programme, Wellcome Sanger Institute, Hinxton, UK., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita 565-0871, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita 565-0871, Japan., Palotie AV; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Pasaniuc B; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.; Institute of Precision Health, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ritchie MD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sanna S; University of Groningen, UMCG, Department of Genetics, Groningen, the Netherlands.; Institute for Genetics and Biomedical Research (IRGB), National Research Council (CNR), Cagliari, Italy., Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Precision Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Stefansson K; deCODE Genetics/Amgen, Inc., 101 Reykjavik, Iceland., van Heel DA; Blizard Institute, Queen Mary University of London, London, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Zöllner S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Martin AR; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Daly MJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Publikováno v: Cell genomics [Cell Genom] 2022 Oct 12; Vol. 2 (10), pp. 100192. Date of Electronic Publication: 2022 Oct 12 (Print Publication: 2022).