Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lee M. Wheldon"'
Autor:
Matthew Vassey, Rininta Firdaus, Akhmed Aslam, Lee M. Wheldon, Neil J. Oldfield, Dlawer A. A. Ala’Aldeen, Karl G. Wooldridge
Publikováno v:
Cellular Microbiology, Vol 2023 (2023)
Neisseria meningitidis is the most frequent cause of bacterial meningitis and is one of the few bacterial pathogens that can breach the blood-brain barrier (BBB). The 37/67 kDa laminin receptor (LamR) was previously identified as a receptor mediating
Externí odkaz:
https://doaj.org/article/80812655905a4ffbb15e7e36e8d17994
Autor:
Martin J. Blythe, Ayhan Kocer, Alejandro Rubio-Roldan, Tom Giles, Abdulkadir Abakir, Côme Ialy-Radio, Lee M. Wheldon, Oxana Bereshchenko, Stefano Bruscoli, Alexander Kondrashov, Joël R. Drevet, Richard D. Emes, Andrew D. Johnson, John R. McCarrey, Daniel Gackowski, Ryszard Olinski, Julie Cocquet, Jose L. Garcia-Perez, Alexey Ruzov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Blythe et al investigate the patterns of oxidized forms of the 5-methylcytosine DNA modification during spermatogenesis. They find that open reading frames of evolutionarily young and transcriptionally active LINE-1 retrotransposons are enriched in 5
Externí odkaz:
https://doaj.org/article/404f4300a2c74fb1b5b1fc739c852701
Autor:
Lee M. Wheldon, Abdulkadir Abakir, Zoltan Ferjentsik, Tatiana Dudnakova, Stephanie Strohbuecker, Denise Christie, Nan Dai, Shengxi Guan, Jeremy M. Foster, Ivan R. Corrêa, Jr., Matthew Loose, James E. Dixon, Virginie Sottile, Andrew D. Johnson, Alexey Ruzov
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1353-1361 (2014)
5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Both 5fC and 5
Externí odkaz:
https://doaj.org/article/3adf262477e140eeb7c0a0a39912519c
Autor:
Fulwah Alqahtani, Jafar Mahdavi, Lee M. Wheldon, Matthew Vassey, Necmettin Pirinccioglu, Pierre-Joseph Royer, Suzan M. Qarani, Shaun Morroll, Jeroen Stoof, Nicholas D. Holliday, Siew Y. Teo, Neil J. Oldfield, Karl G. Wooldridge, Dlawer A. A. Ala'Aldeen
Publikováno v:
Open Biology, Vol 4, Iss 10 (2014)
The non-integrin laminin receptor (LAMR1/RPSA) and galectin-3 (Gal-3) are multi-functional host molecules with roles in diverse pathological processes, particularly of infectious or oncogenic origins. Using bimolecular fluorescence complementation an
Externí odkaz:
https://doaj.org/article/2a4e4f02da244b43abedfc6bc31fd573
Autor:
Jafar Mahdavi, Pierre-Joseph Royer, Hong S. Sjölinder, Sheyda Azimi, Tim Self, Jeroen Stoof, Lee M. Wheldon, Kristoffer Brännström, Raymond Wilson, Joanna Moreton, James W. B. Moir, Carina Sihlbom, Thomas Borén, Ann-Beth Jonsson, Panos Soultanas, Dlawer A. A. Ala'Aldeen
Publikováno v:
Open Biology, Vol 3, Iss 10 (2013)
Interactions between commensal pathogens and hosts are critical for disease development but the underlying mechanisms for switching between the commensal and virulent states are unknown. We show that the human pathogen Neisseria meningitidis, the lea
Externí odkaz:
https://doaj.org/article/0922dc73be34404db1e8d80e0eb1dffe
Autor:
Jose L. Garcia-Perez, Côme Ialy-Radio, Alejandro Rubio-Roldan, Julie Cocquet, Oxana Bereshchenko, Joël R. Drevet, Stefano Bruscoli, Ryszard Olinski, Alexey Ruzov, Daniel Gackowski, Abdulkadir Abakir, Tom C. Giles, Richard D. Emes, Martin J. Blythe, Alexander Kondrashov, Andrew D. Johnson, John R. McCarrey, Ayhan Kocer, Lee M. Wheldon
Publikováno v:
Communications Biology
Communications Biology, 2021, 4, pp.691. ⟨10.1038/s42003-021-02217-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, 2021, 4, pp.691. ⟨10.1038/s42003-021-02217-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Chromatin of male and female gametes undergoes a number of reprogramming events during the transition from germ cell to embryonic developmental programs. Although the rearrangement of DNA methylation patterns occurring in the zygote has been extensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6a12ff311170c5847fa1e587d0812c
https://hal.science/hal-03670149
https://hal.science/hal-03670149
SummaryNeisseria meningitidisremains an important cause of human disease. It is highly adapted to the human host – its only known reservoir. Adaptations to the host environment include many specific interactions with human molecules including iron-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f409d9b38dc94facb0de009d31bdeef9
Autor:
Luisa Martinez-Pomares, Susan Liddell, Marcos Castellanos, Richard D. Emes, Timothy A. Giles, Mjc Alcocer, Lee M. Wheldon, Sean T. May, Nuzul Noorahya Jambari
Publikováno v:
Allergy
Autor:
Lee M. Wheldon, Zoltan Ferjentsik, Andrew D. Johnson, Anthony Alioui, Abdulkadir Abakir, Alexey Ruzov
Publikováno v:
Nucleus
5-Methylcytosine (5-mC) is an epigenetic modification associated with gene repression. Recent studies demonstrated that 5-mC can be enzymatically oxidised into 5-hydroxymethylcytosine and further into 5-formylcytosine (5-fC) and 5-carboxylcytsine (5-
Publikováno v:
Epigenetic Methods in Neuroscience Research ISBN: 9781493927531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a65ff0d2561149d15f079351a3ef8b5
https://doi.org/10.1007/978-1-4939-2754-8_8
https://doi.org/10.1007/978-1-4939-2754-8_8