Zobrazeno 1 - 10
of 489
pro vyhledávání: '"Lee M. Ellis"'
Autor:
Fan Fan, Susmita Ghosh, Reid Powell, Jason Roszik, Yongsun Park, Mary Sobieski, Alexey Sorokin, Clifford Stephan, Scott Kopetz, Lee M. Ellis, Rajat Bhattacharya
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Metastatic colorectal cancer (mCRC) is the second leading cause of cancer deaths in the United States. More than 50% of patients with mCRC harbor mutations of the oncogenic driver RAS (KRAS or NRAS). Because directly targeting most mutations of RAS i
Externí odkaz:
https://doaj.org/article/644cc5d8a72f4beda2d14f579c4b4b9a
Autor:
Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 11-14 (2021)
Externí odkaz:
https://doaj.org/article/c3fa45c6e32349f68ffd7fcab701dc16
Autor:
Fan Fan, Jason Roszik, Ling Xia, Susmita Ghosh, Rui Wang, Xiangcang Ye, David Hawke, Lee M. Ellis, Rajat Bhattacharya
Publikováno v:
Cancers, Vol 14, Iss 8, p 1977 (2022)
Proteins that interact with cytoskeletal elements play important roles in cell division and are potentially important targets for therapy in cancer. Cytospin-A (CYTSA), a protein known to interact with actin and microtubules, has been previously desc
Externí odkaz:
https://doaj.org/article/df52dac52e72414c9d724507a17aee3a
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
Externí odkaz:
https://doaj.org/article/464b02794d404eca8042aa07174e5279
Autor:
Guohui Wan, Xinna Zhang, Robert R. Langley, Yunhua Liu, Xiaoxiao Hu, Cecil Han, Guang Peng, Lee M. Ellis, Stephen N. Jones, Xiongbin Lu
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 2100-2112 (2013)
Expression of microRNAs (miRNAs) involves transcription of miRNA genes and maturation of the primary transcripts. Recent studies have shown that posttranscriptional processing of primary and precursor miRNAs is induced after DNA damage through regula
Externí odkaz:
https://doaj.org/article/9cbd6a84242d4851b37977e2eb99e653
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT The American Academy of Microbiology convened a colloquium to discuss problems in the biological sciences, with emphasis on identifying mechanisms to improve the quality of research. Participants from various disciplines made six recommendat
Externí odkaz:
https://doaj.org/article/bb75042cd9074d688f7d23b5ceb4d7b5
Autor:
Mian M.K. Shahzad, Lingegowda S. Mangala, Hee Dong Han, Chunhua Lu, Justin Bottsford-Miller, Masato Nishimura, Edna M. Mora, Jeong-Won Lee, Rebecca L. Stone, Chad V. Pecot, Duangmani Thanapprapasr, Ju-Won Roh, Puja Gaur, Maya P. Nair, Yun-Yong Park, Nirupama Sabnis, Michael T. Deavers, Ju-Seog Lee, Lee M. Ellis, Gabriel Lopez-Berestein, Walter J. McConathy, Laszlo Prokai, Andras G. Lacko, Anil K. Sood
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 309-319 (2011)
RNA interference holds tremendous potential as a therapeutic approach, especially in the treatment of malignant tumors. However, efficient and biocompatible delivery methods are needed for systemic delivery of small interfering RNA (siRNA). To mainta
Externí odkaz:
https://doaj.org/article/d2b1e57fbc9c4c7d8cb4be4b81ac9da4
Autor:
Shutaro Ozawa, Hisashi Shinohara, Hiro-omi Kanayama, Christiane J. Bruns, Corazon D. Bucana, Lee M. Ellis, Darren W. Davis, Isaiah J. Fidler
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 2, Pp 154-164 (2001)
The purpose of this study was to determine whether systemic administration of interferon-alpha (IFN-α) can inhibit liver metastasis produced in nude mice by human colon cancer cells. KM12L4 (IFN-α-sensitive) or KM12L4 IFNR (IFN-α-resistant) cells
Externí odkaz:
https://doaj.org/article/311384f175284b0aa490cbcac8cd33ce
Autor:
Lee M. Ellis, Xiongbin Lu, Jing Wang, George A. Calin, Xiaofeng Zheng, Cristina Ivan, Ling Xia, Rui Wang, Delphine R. Boulbes, Seth Bellister, Rajat Bhattacharya, Fan Fan, Xiangcang Ye
Supplementary Figure Legend. Supplementary Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67de21538f835e8e8297f6e20d6bdce3
https://doi.org/10.1158/1541-7786.22511929.v1
https://doi.org/10.1158/1541-7786.22511929.v1
Autor:
Zhang Weihua, Lee M. Ellis, Seth Bellister, Fan Fan, Jia Lu, Ling Xia, Elizabeth Dupre, Guang Gao, Rajat Bhattacharya, Xiangcang Ye, Federico Tozzi, Lakshmi Reddy Bollu, Yunfei Zhou
PDF file - 840K, Suppl. Figure 1. Conversion of CPT-11 (irinotican) to SN-38 by carboxylesterase; Suppl. Figure 2. Western blot analysis of the basal expression status of ACLy in a panel of colon cancer cell (CRC) lines; Suppl. Figure 3. Overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c443dbce42076dba316e2c0b8ed925c
https://doi.org/10.1158/1535-7163.22498119
https://doi.org/10.1158/1535-7163.22498119