Zobrazeno 1 - 10
of 324
pro vyhledávání: '"Lee M Nadler"'
Autor:
Marcus O Butler, Osamu Imataki, Yoshihiro Yamashita, Makito Tanaka, Sascha Ansén, Alla Berezovskaya, Genita Metzler, Matthew I Milstein, Mary M Mooney, Andrew P Murray, Hiroyuki Mano, Lee M Nadler, Naoto Hirano
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30229 (2012)
Using in vivo mouse models, the mechanisms of CD4+ T cell help have been intensively investigated. However, a mechanistic analysis of human CD4+ T cell help is largely lacking. Our goal was to elucidate the mechanisms of human CD4+ T cell help of CD8
Externí odkaz:
https://doaj.org/article/ecfdc6166ac84d34b817552f4d642e0d
Autor:
Sara Maia, Marc Pelletier, Jixin Ding, Yen-Ming Hsu, Stephen E Sallan, Sambasiva P Rao, Lee M Nadler, Angelo A Cardoso
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20787 (2011)
Despite exhibiting oncogenic events, patient's leukemia cells are responsive and dependent on signals from their malignant bone marrow (BM) microenvironment, which modulate their survival, cell cycle progression, trafficking and resistance to chemoth
Externí odkaz:
https://doaj.org/article/772320a7089b46369da3e134c7c6aa23
Autor:
Elaine H. Morrato, Lindsay A. Lennox, Elaina R. Sendro, Anne L. Schuster, Harold A. Pincus, Jennifer Humensky, Gary S. Firestein, Lee M. Nadler, Robert Toto, Steven E. Reis
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 515-528 (2020)
Abstract Introduction: The Clinical and Translational Science Award (CTSA) Program is a Consortium of nearly 60 academic medical research centers across the USA and a natural network for evaluating the spread and uptake of translational research inn
Externí odkaz:
https://doaj.org/article/48d1008d85e44bb3b4d0c85a582c4181
Autor:
Lee M. Nadler, Robert L. Coffman, George Demetri, Patrick Wen, Jeffrey Morgan, Jeffrey Kutok, Xiaochun Li, Donna Neuberg, Paul Sims, Suzanne George, Kate Russell, Steven Rivoli, Jill Angelosanto, John Evans, Thomas Brenn, Linda Drury, Holger Kanzler, Jeffrey Davies, W. Nicholas Haining
Supplementary Data from CpG Oligodeoxynucleotides Alter Lymphocyte and Dendritic Cell Trafficking in Humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9a9e677a7e9db4aaa9e8a531e30862
https://doi.org/10.1158/1078-0432.22439638.v1
https://doi.org/10.1158/1078-0432.22439638.v1
Autor:
Lee M. Nadler, Robert L. Coffman, George Demetri, Patrick Wen, Jeffrey Morgan, Jeffrey Kutok, Xiaochun Li, Donna Neuberg, Paul Sims, Suzanne George, Kate Russell, Steven Rivoli, Jill Angelosanto, John Evans, Thomas Brenn, Linda Drury, Holger Kanzler, Jeffrey Davies, W. Nicholas Haining
Purpose: CpG oligodeoxynucleotides (CpG-ODN) are being investigated as cancer vaccine adjuvants because they mature plasmacytoid dendritic cells (PDC) into potent antigen-presenting cells. CpG-ODN also induce PDC to secrete chemokines that alter lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d711fbde563e84f3fee23c9e76d03378
https://doi.org/10.1158/1078-0432.c.6517075.v1
https://doi.org/10.1158/1078-0432.c.6517075.v1
Autor:
Eva C. Guinan, Lee M. Nadler, Richard E. Champlin, Peter F. Thall, Laurence J. Cooper, Marcos de Lima, Thomas R. Spitzer, Bimalangshu R. Dey, Ami J. Shah, Neena Kapoor, Christopher R. Cogle, John R. Wingard, Lisa L. Brennan, Jeff K. Davies
Purpose: Allogeneic hematopoietic stem-cell transplantation (HSCT) is a curative treatment for many hematologic cancers. Use of haploidentical (mismatched) donors increases HSCT availability but is limited by severe graft-versus-host disease (GvHD) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4657df4073dbc61e5035bb4eacd58ef8
https://doi.org/10.1158/1078-0432.c.6527625
https://doi.org/10.1158/1078-0432.c.6527625
Autor:
Eva C. Guinan, Lee M. Nadler, Richard E. Champlin, Peter F. Thall, Laurence J. Cooper, Marcos de Lima, Thomas R. Spitzer, Bimalangshu R. Dey, Ami J. Shah, Neena Kapoor, Christopher R. Cogle, John R. Wingard, Lisa L. Brennan, Jeff K. Davies
Table S1 Patients, donors, HLA-mismatches and conditioning; Table S2 Cell doses in stem cell transplant, engraftment and chimerism; Table S3 ADLI dose and timing and allostimulator source; Table S4 Patient outcomes; Figure S1 Schema for clinical stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a511c5315fc2fb51fb247093d838fa2
https://doi.org/10.1158/1078-0432.22470588
https://doi.org/10.1158/1078-0432.22470588
Autor:
Naoto Hirano, Lee M. Nadler, Alla Berezovskaya, Osamu Imataki, Sascha Ansén, Marcus O. Butler, Makito Tanaka
Purpose: In previous cancer vaccine clinical trials targeting survivin, induction of specific CD8+ T-cell responses did not consistently lead to clinical responses. Considering the critical role of CD4+ T-cell help in generating antitumor immunity, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d904e0ea75e40f43a3bdf608b6edfa6
https://doi.org/10.1158/1078-0432.c.6520191
https://doi.org/10.1158/1078-0432.c.6520191