Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Lee L, Marshall"'
Autor:
Carissa Chen, Scott Lee, Katherine G. Zyner, Milan Fernando, Victoria Nemeruck, Emilie Wong, Lee L. Marshall, Jesse R. Wark, Nader Aryamanesh, Patrick P.L. Tam, Mark E. Graham, Anai Gonzalez-Cordero, Pengyi Yang
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114219- (2024)
Summary: Defining the molecular networks orchestrating human brain formation is crucial for understanding neurodevelopment and neurological disorders. Challenges in acquiring early brain tissue have incentivized the use of three-dimensional human plu
Externí odkaz:
https://doaj.org/article/8a7fd637d50344138b8dbe6664cdb3e7
Autor:
Juozas Gordevicius, Peipei Li, Lee L. Marshall, Bryan A. Killinger, Sean Lang, Elizabeth Ensink, Nathan C. Kuhn, Wei Cui, Nazia Maroof, Roberta Lauria, Christina Rueb, Juliane Siebourg-Polster, Pierre Maliver, Jared Lamp, Irving Vega, Fredric P. Manfredsson, Markus Britschgi, Viviane Labrie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Dysfunction of the gastrointestinal system, and to the autophagy lysososmal pathway (ALP) have been reported in Parkinson’s disease. Here the authors report epigenetic disruption of ALP related genes in the appendix of individuals with Parkinson’
Externí odkaz:
https://doaj.org/article/f9f6d09087434442861f49df6420270e
Autor:
Aoji Xie, Elizabeth Ensink, Peipei Li, Juozas Gordevičius, Lee L. Marshall, Sonia George, John Andrew Pospisilik, Velma T.E. Aho, Madelyn C. Houser, Pedro A.B. Pereira, Knut Rudi, Lars Paulin, Malú G. Tansey, Petri Auvinen, Patrik Brundin, Lena Brundin, Viviane Labrie, Filip Scheperjans
Background The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease (PD) patients. It has been recently demonstrated that PD patients have reduced fecal levels of the potent epigenetic modulator butyrate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c898ac3e71214da9bb34cf27ae2f59
http://hdl.handle.net/10138/352161
http://hdl.handle.net/10138/352161
Autor:
Bryan A. Killinger, Lee L. Marshall, Diptaman Chatterjee, Yaping Chu, Jose Bras, Rita Guerreiro, Jeffrey H. Kordower
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The intracellular misfolding and accumulation of alpha-synuclein into structures collectively called Lewy pathology (LP) is a central phenomenon for the pathogenesis of synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b033becdaa713e7c1f1ebae097584a
https://doi.org/10.1073/pnas.2114405119
https://doi.org/10.1073/pnas.2114405119
Autor:
Lee L, Marshall, Bryan A, Killinger, Elizabeth, Ensink, Peipei, Li, Katie X, Li, Wei, Cui, Noah, Lubben, Matthew, Weiland, Xinhe, Wang, Juozas, Gordevicius, Gerhard A, Coetzee, Jiyan, Ma, Stefan, Jovinge, Viviane, Labrie
Publikováno v:
Nature neuroscience. 23(10)
Parkinson's disease (PD) pathogenesis may involve the epigenetic control of enhancers that modify neuronal functions. Here, we comprehensively examine DNA methylation at enhancers, genome-wide, in neurons of patients with PD and of control individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18422353ad46f27bd4805557f4fdc67c
https://pubmed.ncbi.nlm.nih.gov/33245171
https://pubmed.ncbi.nlm.nih.gov/33245171
Publikováno v:
Journal of Chemical Biology. 7:67-76
Hereditary sensory neuropathy type 1 (HSN-1) is an autosomal dominant neurodegenerative disease caused by missense mutations in the SPTLC1 gene. The SPTLC1 protein is part of the SPT enzyme which is a ubiquitously expressed, critical and thus highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45b3c13a328c35dd1fb173833876596
https://doi.org/10.1007/s12154-014-0108-y
https://doi.org/10.1007/s12154-014-0108-y
Autor:
Eremia, Irina-Anca1,2 (AUTHOR) florina.cofaru@drd.umfcd.ro, Anghel, Cătălin-Alexandru1 (AUTHOR) catalin.anghel@stud.umfcd.ro, Cofaru, Florina-Alexandra2 (AUTHOR), Nica, Silvia1,2 (AUTHOR)
Publikováno v:
Diagnostics (2075-4418). Aug2024, Vol. 14 Issue 15, p1592. 11p.
Autor:
Uemura, Hisashi1 (AUTHOR), Matsue, Hajime1 (AUTHOR), Suehiro, Yasuo1 (AUTHOR), Nakagawa, Takaya1 (AUTHOR), Satoh, Ayaka1 (AUTHOR), Teshima, Yoshio2 (AUTHOR), Bungo, Masashi2 (AUTHOR), Satoh, Hisashi1 (AUTHOR) h-satoh@mail.hts-hsp.com
Publikováno v:
Journal of Medical Case Reports. 6/21/2024, Vol. 18 Issue 1, p1-6. 6p.
Autor:
Kortli, Said1 (AUTHOR) kortlisaid@outlook.com, Andrianjafy, Hery1 (AUTHOR)
Publikováno v:
International Journal of Emergency Medicine. 5/8/2024, Vol. 17 Issue 1, p1-5. 5p.
Autor:
Margaris, Ioannis1, Triantafyllou, Tania2, Sidiropoulos, Theodoros A.1, Sideris, Giorgos2, Theodorou, Dimitrios2, Arkadopoulos, Nikolaos1, Michalopoulos, Nikolaos V.1
Publikováno v:
Annals of Gastroenterology. 2024, Vol. 37 Issue 2, p156-171. 16p.