Výsledky vyhledávání - "Lee Koyavski"

Sex-Dependent Sensory Phenotypes and Related Transcriptomic Expression Profiles Are Differentially Affected by Angelman Syndrome

Autor: Lital Sharvit, Yonatan Feuermann, Lilach Simchi, Julia Panov, Prudhvi Raj Rayi, Hanoch Kaphzan, Lee Koyavski

Publikováno v: Molecular Neurobiology. 56:5998-6016

Angelman syndrome (AS) is a genetic disorder which entails autism, intellectual disability, lack of speech, motor deficits, and seizure susceptibility. It is caused by the lack of UBE3A protein expression, which is an E3-ubiquitin ligase. Despite AS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7aa9e6b462923aedf8dd7f267dad73e
https://doi.org/10.1007/s12035-019-1503-8

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α1-Na/K-ATPase inhibition rescues aberrant dendritic calcium dynamics and memory deficits in the hippocampus of an Angelman syndrome mouse model

Autor: Darpan Chakraborty, Lee Koyavski, Alexei Y. Bagrov, Hanoch Kaphzan, Prudhvi Raj Rayi

Publikováno v: Progress in neurobiology. 182

Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of function of the maternal copy of the UBE3A gene. Previous studies reported an increase in α1-Na/K-ATPase (α1-NaKA) expression in the AS hippocampus at the age of 2 weeks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105b5d3a99376a8487792ae223db23ef
https://pubmed.ncbi.nlm.nih.gov/31401139

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