Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lee Kingston"'
Autor:
Rossana Passannante, Vanessa Gómez-Vallejo, Maialen Sagartzazu-Aizpurua, Laura Vignau Arsuaga, Pablo Marco-Moreno, Garazi Aldanondo, Ainara Vallejo-Illarramendi, Pablo Aguiar, Unai Cossío, Abraham Martín, Jonas Bergare, Lee Kingston, Charles S. Elmore, Miguel Angel Morcillo, Pablo Ferrón, Jesus M. Aizpurua, Jordi Llop
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 253 (2023)
Background and objective: The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET) is an ideal technique to obtain both biodistribution and pharmacok
Externí odkaz:
https://doaj.org/article/ed7d132499034dc9b7f57f0c9ecdfc0f
Autor:
Mahabuba Jahan, Peter Johnström, Ram K. Selvaraju, Marie Svedberg, Maria Sörhede Winzell, Jenny Bernström, Lee Kingston, Magnus Schou, Zhisheng Jia, Stanko Skrtic, Lars Johansson, Olle Korsgren, Lars Farde, Christer Halldin, Olof Eriksson
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background The G-protein-coupled receptor 44 (GPR44) is a beta cell-restricted target that may serve as a marker for beta cell mass (BCM) given the development of a suitable PET ligand. Methods The binding characteristics of the selected can
Externí odkaz:
https://doaj.org/article/adeebd397411476c89f34e68e0105f08
Autor:
Orlagh M. Feeney, Katie Ardipradja, Ka Fung Noi, Dharmini Mehta, Robert De Rose, Daniel Yuen, Angus P.R. Johnston, Lee Kingston, Cecilia Ericsson, Charles S. Elmore, Richard Hufton, David J. Owen, Marianne B. Ashford, Christopher J.H. Porter
Publikováno v:
Journal of Controlled Release. 348:420-430
As a malignant tumour of lymphatic origin, B-cell lymphoma represents a significant challenge for drug delivery, where effective therapies must access malignant cells in the blood, organs and lymphatics while avoiding off-target toxicity. Subcutaneou
Autor:
Gianluca Destro, Kaisa Horkka, Olivier Loreau, David‐Alexandre Buisson, Lee Kingston, Antonio Del Vecchio, Magnus Schou, Charles S. Elmore, Frédéric Taran, Thibault Cantat, Davide Audisio
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (32), pp.13490-13495. ⟨10.1002/anie.202002341⟩
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition, 2020, 59 (32), pp.13490-13495. ⟨10.1002/anie.202002341⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (32), pp.13490-13495. ⟨10.1002/anie.202002341⟩
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition, 2020, 59 (32), pp.13490-13495. ⟨10.1002/anie.202002341⟩
A transition‐metal‐free carbon isotope exchange procedure on phenyl acetic acids is described. Utilizing the universal precursor CO2, this protocol allows the carbon isotope to be inserted into the carboxylic acid position, with no need of precur
Autor:
Markus Artelsmair, Patricia Miranda‐Azpiazu, Lee Kingston, Jonas Bergare, Magnus Schou, Andrea Varrone, Charles S. Elmore
The immune system is implicated in the pathology of neurodegenerative disorders. The C‐C chemokine receptor 2 (CCR2) is one of the key targets involved in the activation of the immune system. A suitable ligand for CCR2 could be a useful tool to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::cd49a8ce4cdadd5ff76fad7a84eaaf07
https://zenodo.org/record/3992592
https://zenodo.org/record/3992592
Autor:
Markus, Artelsmair, Patricia, Miranda-Azpiazu, Lee, Kingston, Jonas, Bergare, Magnus, Schou, Andrea, Varrone, Charles S, Elmore
Publikováno v:
Journal of Labelled Compounds & Radiopharmaceuticals
The immune system is implicated in the pathology of neurodegenerative disorders. The C‐C chemokine receptor 2 (CCR2) is one of the key targets involved in the activation of the immune system. A suitable ligand for CCR2 could be a useful tool to stu
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 57(11)
The specific activity (SA) values determined using two different methods were compared for a set of tritium-labeled and carbon-14-labeled compounds. The methods employed were as follows: (a) liquid chromatography/mass spectrometry (LC/MS) isotopic pe