Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Lee Jun C. Wong"'
Autor:
Wen-Chen Liang, Yuh-Jyh Jong, Chien-Hua Wang, Chen-Hua Wang, Xia Tian, Wan-Zi Chen, Tzu-Min Kan, Narihiro Minami, Ichizo Nishino, Lee-Jun C. Wong
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Limb-girdle muscular dystrophy (LGMD) is a genetically heterogeneous, hereditary disease characterized by limb-girdle weakness and histologically dystrophic changes. The prevalence of each subtype of LGMD varies among different et
Externí odkaz:
https://doaj.org/article/b9d1018908994e309627ccc9fcde0613
Autor:
Zhisheng Yuan, Baiyu Li, Mingchu Xu, Emmanuel Y. Chang, Huajin Li, Lizhu Yang, Shijing Wu, Zachry T. Soens, Yumei Li, Lee-Jun C. Wong, Richard A. Lewis, Ruifang Sui, Rui Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Inherited retinal dystrophies (IRDs) are a clinically and genetically heterogeneous group of Mendelian disorders primarily affecting photoreceptor cells. The same IRD-causing variant may lead to different retinal symptoms, demonstrating plei
Externí odkaz:
https://doaj.org/article/5fb3890276534bc0b43f0cb5ca6410ac
Autor:
Jun Hyoung Park, Sajna Vithayathil, Santosh Kumar, Pi-Lin Sung, Lacey Elizabeth Dobrolecki, Vasanta Putluri, Vadiraja B. Bhat, Salil Kumar Bhowmik, Vineet Gupta, Kavisha Arora, Danli Wu, Efrosini Tsouko, Yiqun Zhang, Suman Maity, Taraka R. Donti, Brett H. Graham, Daniel E. Frigo, Cristian Coarfa, Patricia Yotnda, Nagireddy Putluri, Arun Sreekumar, Michael T. Lewis, Chad J. Creighton, Lee-Jun C. Wong, Benny Abraham Kaipparettu
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2154-2165 (2016)
Transmitochondrial cybrids and multiple OMICs approaches were used to understand mitochondrial reprogramming and mitochondria-regulated cancer pathways in triple-negative breast cancer (TNBC). Analysis of cybrids and established breast cancer (BC) ce
Externí odkaz:
https://doaj.org/article/28c753416ec244359418fa4cf4d08719
Supplementary Tables 1-3 from Mitochondrial Genetic Background Modifies Breast Cancer Risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442cecb26de1daf1115feeafa8bf6c39
https://doi.org/10.1158/0008-5472.22366743.v1
https://doi.org/10.1158/0008-5472.22366743.v1
Inefficient mitochondrial electron transport chain (ETC) function has been implicated in the vicious cycle of reactive oxygen species (ROS) production that may predispose an individual to late onset diseases, such as diabetes, hypertension, and cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe666315c5572caf0cd69c06c5b0e13
https://doi.org/10.1158/0008-5472.c.6495267.v1
https://doi.org/10.1158/0008-5472.c.6495267.v1
Autor:
Benny Abraham Kaipparettu, Yewei Ma, Jun Hyoung Park, Tin-Lap Lee, Yiqun Zhang, Patricia Yotnda, Chad J Creighton, Wai-Yee Chan, Lee-Jun C Wong
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221671 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0061747.].
Externí odkaz:
https://doaj.org/article/9a2532d08fda46968ef88806ae091664
Autor:
Jorge L. Granadillo, Timothy Moss, Richard A. Lewis, Elise G. Austin, Howard Kelfer, Jing Wang, Lee-Jun C. Wong, Fernando Scaglia
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 1, Iss C, Pp 61-65 (2014)
We report a patient harboring a de novo m.5540G>A mutation affecting the MT-TW gene coding for the mitochondrial tryptophan-transfer RNA. This patient presented with atonic–myoclonic epilepsy, bilateral sensorineural hearing loss, ataxia, motor reg
Externí odkaz:
https://doaj.org/article/23872913b5f5440c8a1ac8a2b0fa3d7f
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 1, Iss C, Pp 451-454 (2014)
Defects in two subunits of succinate-CoA ligase encoded by the genes SUCLG1 and SUCLA2 have been identified in mitochondrial DNA (mtDNA) depletion syndromes. Patients generally present with encephalomyopathy and mild methylmalonic acidemia (MMA), how
Externí odkaz:
https://doaj.org/article/7c05f3fc08434b5397e5312071f49562
Autor:
Wen-Chen Liang, Xia Tian, Chung-Yee Yuo, Wan-Zi Chen, Tsu-Min Kan, Yi-Ning Su, Ichizo Nishino, Lee-Jun C Wong, Yuh-Jyh Jong
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183406 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0170517.].
Externí odkaz:
https://doaj.org/article/aad47b1fdccf4f6e8ada95931a624ae6
Autor:
Wen-Chen Liang, Xia Tian, Chung-Yee Yuo, Wan-Zi Chen, Tsu-Min Kan, Yi-Ning Su, Ichizo Nishino, Lee-Jun C Wong, Yuh-Jyh Jong
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170517 (2017)
PURPOSE:Congenital muscular dystrophy (CMD) is a heterogeneous disease entity. The detailed clinical manifestation and causative gene for each subgroup of CMD are quite variable. This study aims to analyze the phenotypes and genotypes of Taiwanese pa
Externí odkaz:
https://doaj.org/article/b3d7bbadbb5b40678cb207ca54b72fb3