Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lee Jollans"'
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
Autor:
Silvia Martinelli, Elmira A. Anderzhanova, Thomas Bajaj, Svenja Wiechmann, Frederik Dethloff, Katja Weckmann, Daniel E. Heinz, Tim Ebert, Jakob Hartmann, Thomas M. Geiger, Michael Döngi, Kathrin Hafner, Max L. Pöhlmann, Lee Jollans, Alexandra Philipsen, Susanne V. Schmidt, Ulrike Schmidt, Giuseppina Maccarrone, Valentin Stein, Felix Hausch, Christoph W. Turck, Mathias V. Schmidt, Anne-Kathrin Gellner, Bernhard Kuster, Nils C. Gassen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Glucocorticoids are associated with stress. Here, the authors show that high levels of glucocorticoid stress promote secretory autophagy of matrix metalloproteinase 9 via a stress responsive chaperone, increasing brain-derived neurotrophic factor pro
Externí odkaz:
https://doaj.org/article/4b82f8ddb5c141baac1137b7deee6057
Autor:
Joanne P.M. Kenney, Laura Milena Rueda-Delgado, Erik O. Hanlon, Lee Jollans, Ian Kelleher, Colm Healy, Niamh Dooley, Conor McCandless, Thomas Frodl, Alexander Leemans, Catherine Lebel, Robert Whelan, Mary Cannon
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 102983- (2022)
It is important to identify accurate markers of psychiatric illness to aid early prediction of disease course. Subclinical psychotic experiences (PEs) are important risk factors for later mental ill-health and suicidal behaviour. This study used mach
Externí odkaz:
https://doaj.org/article/7a3c5738c9a54b608f35361fffd73747
Autor:
Tanja M. Brückl, Victor I. Spoormaker, Philipp G. Sämann, Anna-Katharine Brem, Lara Henco, Darina Czamara, Immanuel Elbau, Norma C. Grandi, Lee Jollans, Anne Kühnel, Laura Leuchs, Dorothee Pöhlchen, Maximilian Schneider, Alina Tontsch, Martin E. Keck, Leonhard Schilbach, Michael Czisch, Susanne Lucae, Angelika Erhardt, Elisabeth B. Binder
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-25 (2020)
Abstract Background A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain circuits or neurobiological pathways. Many of the identified (neuro) biologi
Externí odkaz:
https://doaj.org/article/50af342dc0eb4d89bd4eeae5fa7fd1c9
Autor:
Athina Tzovara, Ishmael Amarreh, Valentina Borghesani, M. Mallar Chakravarty, Elizabeth DuPre, Christian Grefkes, Amelie Haugg, Lee Jollans, Hyang Woon Lee, Sharlene D. Newman, Rosanna K. Olsen, J. Tilak Ratnanather, Gina Rippon, Lucina Q. Uddin, Maria L. Bringas Vega, Michele Veldsman, Tonya White, AmanPreet Badhwar
Publikováno v:
NeuroImage, Vol 229, Iss , Pp 117742- (2021)
Scientific research aims to bring forward innovative ideas and constantly challenges existing knowledge structures and stereotypes. However, women, ethnic and cultural minorities, as well as individuals with disabilities, are systematically discrimin
Externí odkaz:
https://doaj.org/article/102cea4871f74c3896d01ad789f16018
Autor:
Lee Jollans, Robert Whelan
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Despite abundant research into the neurobiology of mental disorders, to date neurobiological insights have had very little impact on psychiatric diagnosis or treatment. In this review, we contend that the search for neuroimaging biomarkers—neuromar
Externí odkaz:
https://doaj.org/article/0e3fc6cf88bf41f2a245cb26e27dc04f
Autor:
Laura M. Rueda-Delgado, Robert Whelan, Hanni Kiiski, Marc Bennett, Laura O'Halloran, Lee Jollans, Nadja Enz, Kathy L. Ruddy, Nigel Vahey, Francesca R Farina
Publikováno v:
International Journal of Psychophysiology. 163:22-34
Stop-signal reaction time (SSRT), the time needed to cancel an already-initiated motor response, quantifies individual differences in inhibitory control. Electrophysiological correlates of SSRT have primarily focused on late event-related potential (
Autor:
Anna-Katherine Brem, Martin E. Keck, Maximilian Schneider, Tanja Brückl, Laura Leuchs, Norma Christine Grandi, Lee Jollans, Alina Tontsch, Philipp G. Sämann, Anne Kühnel, Dorothee Pöhlchen, Darina Czamara, Angelika Erhardt, Immanuel Elbau, Lara Henco, Elisabeth B. Binder, Victor I. Spoormaker, Susanne Lucae, Michael Czisch, Leonhard Schilbach
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-25 (2020)
BMC Psychiatry
BMC Psychiatry
Background A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain circuits or neurobiological pathways. Many of the identified (neuro) biological dysfu
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
Autor:
Felix Hausch, Daniel E. Heinz, Valentin Stein, Ulrike Schmidt, Frederik Dethloff, Lee Jollans, Max L. Pöhlmann, Bernhard Kuster, Katja Weckmann, Kathrin Hafner, Elmira Anderzhanova, Svenja Wiechmann, Thomas M. Geiger, Thomas Bajaj, Jakob Hartmann, Tim Ebert, Christoph W. Turck, Nils C. Gassen, Alexandra Philipsen, Mathias V. Schmidt, Susanne Schmidt, Giuseppina Maccarrone, Michael Döngi, Anne-Kathrin Gellner, Silvia Martinelli
Publikováno v:
Nature Communications, 12(1):4643. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The stress response is an essential mechanism for maintaining homeostasis, and its disruption is implicated in several psychiatric disorders. On the cellular level, stress activates, among other mechanisms, autophagy that regulates homeostasis throug
Autor:
Valentina Borghesani, AmanPreet Badhwar, J. Tilak Ratnanather, Ishmael Amarreh, Michele Veldsman, Lucina Q. Uddin, Elizabeth DuPre, Athina Tzovara, Amelie Haugg, Christian Grefkes, Hyang Woon Lee, Lee Jollans, Maria L.Bringas Vega, Tonya White, Rosanna K. Olsen, Gina Rippon, Sharlene D. Newman, M. Mallar Chakravarty
Publikováno v:
NeuroImage, 229:117742. Academic Press
NeuroImage, Vol 229, Iss, Pp 117742-(2021)
NeuroImage 229, 117742-(2021). doi:10.1016/j.neuroimage.2021.117742
Tzovara, Athina; Amarreh, Ishmael; Borghesani, Valentina; Chakravarty, MM; DuPre, E; Grefkes, C; Haugg, A; Jollans, L; Lee, HW; Newman, SD; Olsen, RK; Ratnanather, JT; Rippon, G; Uddin, LQ; Vega, MLB; Veldsman, M; White, T; Badhwar, A (2021). Embracing diversity and inclusivity in an academic setting: Insights from the Organization for Human Brain Mapping. NeuroImage, 229(117742), p. 117742. Elsevier 10.1016/j.neuroimage.2021.117742
NeuroImage, Vol 229, Iss, Pp 117742-(2021)
NeuroImage 229, 117742-(2021). doi:10.1016/j.neuroimage.2021.117742
Tzovara, Athina; Amarreh, Ishmael; Borghesani, Valentina; Chakravarty, MM; DuPre, E; Grefkes, C; Haugg, A; Jollans, L; Lee, HW; Newman, SD; Olsen, RK; Ratnanather, JT; Rippon, G; Uddin, LQ; Vega, MLB; Veldsman, M; White, T; Badhwar, A (2021). Embracing diversity and inclusivity in an academic setting: Insights from the Organization for Human Brain Mapping. NeuroImage, 229(117742), p. 117742. Elsevier 10.1016/j.neuroimage.2021.117742
Scientific research aims to bring forward innovative ideas and constantly challenges existing knowledge structures and stereotypes. However, women, ethnic and cultural minorities, as well as individuals with disabilities, are systematically discrimin
Autor:
Rory Boyle, Silvin P. Knight, Görsev Yener, Ian H. Robertson, Jason P. McMorrow, Daniel Carey, Rossella Rizzo, Laura M. Rueda-Delgado, Robert Whelan, Derya Durusu Emek-Savaş, Yaakov Stern, Lee Jollans, Rose Anne Kenny
Publikováno v:
Brain Imaging Behav
Brain-predicted age difference scores are calculated by subtracting chronological age from ‘brain’ age. Positive scores reflect accelerated ageing and are associated with increased mortality risk and poorer physical function. To date, however, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955419f3995f47d514db90762d4dbc29
https://europepmc.org/articles/PMC7500565/
https://europepmc.org/articles/PMC7500565/