Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lee J Byrne"'
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4670 (2009)
BACKGROUND:Yeast (Saccharomyces cerevisiae) prions are efficiently propagated and the on-going generation and transmission of prion seeds (propagons) to daughter cells during cell division ensures a high degree of mitotic stability. The reversible in
Externí odkaz:
https://doaj.org/article/191603b2d1474e8d96aa3a0cb7ded9de
Autor:
Jessica E. Holder, Christopher Ferguson, Elisabete Oliveira, Carlos Lodeiro, Carol M. Trim, Lee J. Byrne, Emilia Bertolo, Cornelia M. Wilson
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is a global health problem affecting millions of people each year. Non-small cell lung cancer (NSCLC) is the most common form of lung cancer with various conventional treatment available in the clinic. Application of these treatments alon
Externí odkaz:
https://doaj.org/article/ff4657231f1c4ca38df728b6c2c7d2dc
Publikováno v:
Progress in medicinal chemistry. 60
Difficult drug targets are becoming the normal course of business in drug discovery, sometimes due to large interacting surfaces or only small differences in selectivity regions. For these, a different approach is merited: compounds lying somewhere b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04f3890839ca97f0c5ede56aaef7bab7
https://pubmed.ncbi.nlm.nih.gov/34147202
https://pubmed.ncbi.nlm.nih.gov/34147202
Autor:
Waqas Khokhar, Musa A. Hassan, Anireddy S. N. Reddy, Saurabh Chaudhary, Ibtissam Jabre, Lee J. Byrne, Naeem H. Syed
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Khokhar, W, Hassan, M, Reddy, A S N, Chaudhary, S, Jabre, I, Byrne, L J & Syed, N H 2019, ' Genome-wide identification of splicing quantitative trait loci (sQTL) in diverse ecotypes of Arabidopsis thaliana ', Frontiers in plant science, pp. 1160 . https://doi.org/10.3389/fpls.2019.01160
Khokhar, W, Hassan, M, Reddy, A S N, Chaudhary, S, Jabre, I, Byrne, L J & Syed, N H 2019, ' Genome-wide identification of splicing quantitative trait loci (sQTL) in diverse ecotypes of Arabidopsis thaliana ', Frontiers in plant science, pp. 1160 . https://doi.org/10.3389/fpls.2019.01160
Alternative splicing (AS) of pre-mRNAs contributes to transcriptome diversity and enables plants to generate different protein isoforms from a single gene and/or fine-tune gene expression during different development stages and environmental changes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab0051a4c3642ae5fe3bd3a3702a708
https://www.frontiersin.org/article/10.3389/fpls.2019.01160/full
https://www.frontiersin.org/article/10.3389/fpls.2019.01160/full
Autor:
Cornelia M. Wilson, Ibtissam Jabre, Waqas Khokhar, Saurabh Chaudhary, Anireddy S. N. Reddy, Naeem H. Syed, Lee J. Byrne
Publikováno v:
Frontiers in Plant Science
Frontiers in Plant Science, Vol 10 (2019)
Frontiers in Plant Science, Vol 10 (2019)
Plants, unlike animals, exhibit a very high degree of plasticity in their growth and development and employ diverse strategies to cope with the variations during diurnal cycles and stressful conditions. Plants and animals, despite their remarkable mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3212d85e496204951993b976499dd4
https://pubmed.ncbi.nlm.nih.gov/31244866
https://pubmed.ncbi.nlm.nih.gov/31244866
Autor:
Waqas Khokhar, Anireddy S. N. Reddy, Lee J. Byrne, Maria Kalyna, Saurabh Chaudhary, Naeem H. Syed, Ibtissam Jabre, Cornelia M. Wilson
Publikováno v:
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
NUCLEIC ACIDS RESEARCH
Plants display exquisite control over gene expression to elicit appropriate responses under normal and stress conditions. Alternative splicing (AS) of pre-mRNAs, a process that generates two or more transcripts from multi-exon genes, adds another lay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696242289e7966e15aa9eeda56b7c68e
https://pubmed.ncbi.nlm.nih.gov/30793202
https://pubmed.ncbi.nlm.nih.gov/30793202
Autor:
Ateesh Sidhu, Richard A. Williamson, Robert B. Freedman, A. Katrine Wallis, Mark J. Howard, Lloyd W. Ruddock, Lee J. Byrne
Publikováno v:
Biochemical Journal. 423:209-217
PDI (protein disulfide-isomerase) catalyses the formation of native disulfide bonds of secretory proteins in the endoplasmic reticulum. PDI consists of four thioredoxin-like domains, of which two contain redox-active catalytic sites (a and a′), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6397c646846858c208ff8199f21cc656
https://doi.org/10.1042/bj20090565
https://doi.org/10.1042/bj20090565
Publikováno v:
Prion. 1:170-178
The rate of spontaneous change from psi(-) to the psi(+) condition, determined in yeast by states of the Sup35p protein, is briefly discussed together with the conditions necessary for such change to occur. Conditions that promote and which affect th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85d0893934e517f9a1c463bdd9fc66a
https://doi.org/10.4161/pri.1.3.4839
https://doi.org/10.4161/pri.1.3.4839
Publikováno v:
Biometrics. 63:1023-1030
A deterministic formula is commonly used to approximate the expected generation number of a population of growing cells. However, this can give misleading results because it does not allow for natural variation in the times that individual cells take
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35e1db17d60f73c012ea6e38a13718f
https://doi.org/10.1111/j.1541-0420.2007.00780.x
https://doi.org/10.1111/j.1541-0420.2007.00780.x
Publikováno v:
PeerJ
PeerJ, Vol 3, p e1206 (2015)
PeerJ, Vol 3, p e1206 (2015)
The lectin found in the tubers of the Winter Aconite (Eranthis hyemalis) plant is an N-acetyl-D-galactosamine specific Type II Ribosome Inactivating Protein (RIP); Type II RIPs have shown anti-cancer properties, and hence have potential as therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34576d7f4df328ece217d7870d32012d
https://pubmed.ncbi.nlm.nih.gov/26312191
https://pubmed.ncbi.nlm.nih.gov/26312191